Patents by Inventor Murali Krishna Pasumarthy

Murali Krishna Pasumarthy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of nucleic acid compaction
    Patent number: 6506890
    Abstract: An automated nucleic acid compaction device for analyzing and compacting a nucleic acid complex into unimolecular nucleic acid particles. Broadly, the device includes a container support and agitation system; a measuring and testing system; and a dispensing system; all controlled by a control system. The control system controls the support and agitation system and the dispensing system based either on a predetermined formulation or by analysis of feedback data provided by the measuring and testing system. In a preferred embodiment, the device is a real-time measuring and mixing instrument operating in a closed loop system. The preferred embodiment also comprises a monitoring system including a submersible probe which is positioned in the batch solution to provide data to a controller. Once a desired level of nucleic acid compaction is reached, as detected by the monitoring system, the controller stops the dispensing and mixing agitating systems.
    Type: Grant
    Filed: November 28, 2000
    Date of Patent: January 14, 2003
    Inventors: Mark J. Cooper, Tomasz H. Kowalczyk, Murali Krishna Pasumarthy
  • Automated nucleic acid compaction device
    Patent number: 6281005
    Abstract: An automated nucleic acid compaction device for analyzing and compacting a nucleic acid complex into unimolecular nucleic acid particles. Broadly, the device includes a container support and agitation system; a measuring and testing system; and a dispensing system; all controlled by a control system. The control system controls the support and agitation system and the dispensing system based either on a predetermined formulation or by analysis of feedback data provided by the measuring and testing system. In a preferred embodiment, the device is a real-time measuring and mixing instrument operating in a closed loop system. The preferred embodiment also comprises a monitoring system including a submersible probe which is positioned in the batch solution to provide data to a controller. Once a desired level of nucleic acid compaction is reached, as detected by the monitoring system, the controller stops the dispensing and mixing agitating systems.
    Type: Grant
    Filed: May 14, 1999
    Date of Patent: August 28, 2001
    Assignee: Copernicus Therapeutics, Inc.
    Inventors: Hector L. Casal, Mark J. Cooper, Tomasz H. Kowalczyk, Murali Krishna Pasumarthy, Jose C. Perales, Steven J. Torontali