Patents by Inventor Murali Krishna Ukkalam

Murali Krishna Ukkalam has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD OF SYNTHESIS OF COMPOUND FOR DUAL INHIBITION OF JAK2 AND BET
    Publication number: 20220315594
    Abstract: Embodiments of the invention include quinoline compounds and methods of synthesis. Ohm-581 has demonstrated dual inhibition of JAK2 and BET and acts as a therapeutic agent for micosis fungoides (MF) and other hematologic malignancies. Embodiments also include an efficient process for the preparation of Ohm-581 and pharmaceutically acceptable salts. The process is suited for large-scale production of quinoline compounds including Ohm-581.
    Type: Application
    Filed: August 9, 2020
    Publication date: October 6, 2022
    Applicant: OHM ONCOLOGY
    Inventors: Ram Shankar Upadhayaya, Murali Krishna Ukkalam, K Narasimha Sarma