Patents by Inventor Muralikrishna Dantu

Muralikrishna Dantu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for manufacture of ceftriaxone sodium
    Patent number: 7470786
    Abstract: An improved process for preparation of ceftriaxone sodium of formula (II), is disclosed.
    Type: Grant
    Filed: September 15, 2006
    Date of Patent: December 30, 2008
    Assignee: Lupin Limited
    Inventors: Debashish Datta, Muralikrishna Dantu, Pollepeddi Lakshmi Narayana Sharma, Brijkishore Mishra
  • Intermediates for synthesis of cephalosporins and process for preparation of such intermediates
    Patent number: 7452990
    Abstract: A novel 4-halo-2-oxyimino-3-oxo butyric acid-N,N-dimethyl formiminium chloride chlorosulfate of formula (I) useful in the preparation of cephalosporin antibiotics wherein X is chlorine or bromine; R is hydrogen, C1-4 alkyl group, an easily removable hydroxyl protective group, —CH2COOR5, or —C(CH3)2COOR5, wherein R5 is hydrogen or an easily hydrolysable ester group. The compound of formula (I) is prepared by reacting 4-halo-2-oxyimino-3-oxobutyric acid of formula (IV1), wherein X, R and R5 are as defined above, with N,N-dimethylformiminium chloride chlorosulphate of formula (VII) in an organic solvent at a temperature ranging from ?30° C. to ?15° C. The cephalosporins that may be prepared from the intermediate include cefdinir, cefditoren pivoxil, cefepime, cefetamet pivoxil, cefixime, cefmenoxime, cefodizime, cefoselis, cefotaxime, cefpirome, cefpodoxime proxetil, cefquinome, ceftazidime, cefteram pivoxil, ceftiofur, ceftizoxime, ceftriaxone and cefuzonam.
    Type: Grant
    Filed: December 26, 2002
    Date of Patent: November 18, 2008
    Assignee: Lupin Limited
    Inventors: Debashish Datta, Muralikrishna Dantu, Brijkishore Mishra, Pollepeddi Lakshmi Narayana Sharma
  • METHOD FOR THE MANUFACTURE OF CEFTRIAXONE SODIUM
    Publication number: 20080200670
    Abstract: An improved process for preparation of ceftriaxone sodium of formula (II), is disclosed.
    Type: Application
    Filed: January 11, 2008
    Publication date: August 21, 2008
    Applicant: Lupin Limited (Research Park)
    Inventors: Debashish Datta, Muralikrishna Dantu, Pollepeddi Lakshmi Narayana Sharma, Brijkishore Mishra
  • Method for Manufacture of Ceftriaxone Sodium
    Publication number: 20070049749
    Abstract: An improved process for preparation of ceftriaxone sodium of formula (II), is disclosed.
    Type: Application
    Filed: September 15, 2006
    Publication date: March 1, 2007
    Applicant: LUPIN LIMITED (Research Park)
    Inventors: Debashish Datta, Muralikrishna Dantu, Pollepeddi Sharma, Brijkishore Mishra
  • Method For Manufacture of Ceftriaxone Sodium
    Publication number: 20070015917
    Abstract: An improved process for preparation of ceftriaxone sodium of formula (II), is disclosed.
    Type: Application
    Filed: September 15, 2006
    Publication date: January 18, 2007
    Applicant: LUPIN LIMITED (Research Park)
    Inventors: Debashish Datta, Muralikrishna Dantu, Pollepeddi Lakshmi Sharma, Brijkishore Mishra
  • Novel intermediates for synthesis of cephalosporins and process for preparation of such intermediates
    Publication number: 20060135761
    Abstract: A novel 4-halo-2-oxyimino-3-oxo butyric acid-N,N-dimethyl formiminium chloride chlorosulfate of formula (I) useful in the preparation of cephalosporin antibiotics wherein X is chlorine or bromine; R is hydrogen, C1-4 alkyl group, an easily removable hydroxyl protective group, —CH2COOR5, or —C(CH3)2COOR5, wherein R5 is hydrogen or an easily hydrolysable ester group. The compound of formula (I) is prepared by reacting 4-halo-2-oxyimino-3-oxobutyric acid of formula (IV1), wherein X, R and R5 are as defined above, with N,N-dimethylformiminium chloride chlorosulphate of formula (VII) in an organic solvent at a temperature ranging from ?30° C. to ?15° C. The cephalosporins that may be prepared from the intermediate include cefdinir, cefditoren pivoxil, cefepime, cefetamet pivoxil, cefixime, cefmenoxime, cefodizime, cefoselis, cefotaxime, cefpirome, cefpodoxime proxetil, cefquinome, ceftazidime, cefteram pivoxil, ceftiofur, ceftizoxime, ceftriaxone and cefuzonam.
    Type: Application
    Filed: December 26, 2002
    Publication date: June 22, 2006
    Applicant: LUPIN LIMITED
    Inventors: Debashish Datta, Muralikrishna Dantu, Brijkishore Mishra, Pollepeddi Sharma
  • Method for manufacture of ceftriaxone sodium
    Publication number: 20050059820
    Abstract: An improved process for preparation of ceftriaxone sodium of formula (II), is disclosed.
    Type: Application
    Filed: September 25, 2003
    Publication date: March 17, 2005
    Inventors: Debashish Datta, Muralikrishna Dantu, Pollepeddi Sharma, Brijkishore Mishra
  • Method for manufacture of ceftriaxone sodium
    Publication number: 20050059821
    Abstract: An improved process for preparation of ceftriaxone sodium of formula (II), is disclosed.
    Type: Application
    Filed: April 21, 2004
    Publication date: March 17, 2005
    Inventors: Debashish Datta, Muralikrishna Dantu, Pollepeddi Narayana Sharma, Brijkishore Mishra