Abstract: A method for operating a cooling device, a cooling device and a test chamber having a cooling device, a temperature of at least ?80° C. or lower being established at the heat exchanger by means of the cooling device having a cooling circuit comprising a refrigerant, a heat exchanger, an internal heat exchanger, a compressor, a condenser and a controllable expansion element of the cooling device, the refrigerant undergoing a phase transition in the heat exchanger, the refrigerant of a high-pressure side of the cooling circuit being cooled by means of the internal heat exchanger, the cooling of the refrigerant of the high-pressure side by means of the internal heat exchanger being used to reduce an evaporation temperature at the expansion element, a zeotropic refrigerant being used as refrigerant, the expansion element being controlled by means of a control device of the cooling device in such a manner that the refrigerant partially freezes during an expansion at the expansion element.

Abstract: The invention relates to a refrigerant for a cooling device (10) comprising a cooling circuit (11) comprising at least one heat exchanger (12), the refrigerant undergoing a phase transition in the heat exchanger, the refrigerant being a refrigerant mixture composed of a fraction of carbon dioxide (CO2), a fraction of 1,1-difluoroethene and a fraction of at least one other component, wherein the fraction of carbon dioxide in the refrigerant mixture is 45 to 90 mole percent, the fraction of 1,1-difluoroethene being 5 to 40 mole percent.

Abstract: A refrigerant for a cooling device comprising a cooling circuit with at least one heat exchanger, the refrigerant undergoing a phase transition in the heat exchanger, the refrigerant being a refrigerant mixture composed of a mass fraction of carbon dioxide (CO2), a mass fraction of pentafluoroethane (C2HF5) and a mass fraction of at least one other component, wherein the mass fraction of carbon dioxide in the refrigerant mixture is up to 60 mass percent, the mass fraction of pentafluoroethane being 11 to 72 mass percent, the other component being 2,3,3,3-tetrafluoropropene (C3H2F4), the mass fraction of 2,3,3,3-tetrafluoropropene being up to 51 mass percent.

Abstract: The disclosure relates to a method and a device for providing zeotropic refrigerants in which the refrigerant is formed from a refrigerant blend of at least two components, the components being added to a container in the ratio of their respective mass fractions to the refrigerant, and the refrigerant blend being formed in the container, wherein the temperature and/or the pressure in the container is set by means of a control device such that the refrigerant is present exclusively in the gas phase or exclusively in the liquid phase.

Abstract: The invention relates to a refrigerant for a cooling device (10) comprising a cooling circuit (11) comprising at least one heat exchanger (12), the refrigerant undergoing a phase transition in the heat exchanger, the refrigerant being a refrigerant mixture composed of a fraction of carbon dioxide (CO2), a fraction of 1,1-difluoroethene and a fraction of at least one other component, wherein the fraction of carbon dioxide in the refrigerant mixture is 45 to 90 mole percent, the fraction of 1,1-difluoroethene being 5 to 40 mole percent.

Abstract: A method for operating a cooling device, a cooling device and a test chamber having a cooling device, a temperature of at least ?80° C. or lower being established at the heat exchanger by means of the cooling device having a cooling circuit comprising a refrigerant, a heat exchanger, an internal heat exchanger, a compressor, a condenser and a controllable expansion element of the cooling device, the refrigerant undergoing a phase transition in the heat exchanger, the refrigerant of a high-pressure side of the cooling circuit being cooled by means of the internal heat exchanger, the cooling of the refrigerant of the high-pressure side by means of the internal heat exchanger being used to reduce an evaporation temperature at the expansion element, a zeotropic refrigerant being used as refrigerant, the expansion element being controlled by means of a control device of the cooling device in such a manner that the refrigerant partially freezes during an expansion at the expansion element.

Abstract: A refrigerant for a cooling device including a cooling circuit with at least one heat exchanger, the refrigerant undergoing a phase transition in the heat exchanger, the refrigerant being a refrigerant mixture composed of a mass fraction of carbon dioxide, a mass fraction of pentafluoroethane, a mass fraction of difluoromethane and a mass fraction of at least one other component, wherein the mass fraction of carbon dioxide in the refrigerant mixture is 28 to 51 mass percent, the mass fraction of pentafluoroethane being 14.5 to 32 mass percent, the mass fraction of difluoromethane being 14.5 to 38 mass percent, the other component being fluoromethane.

Abstract: A refrigerant for a cooling device comprising a cooling circuit with at least one heat exchanger, the refrigerant undergoing a phase transition in the heat exchanger, the refrigerant being a refrigerant mixture composed of a mass fraction of carbon dioxide (CO2), a mass fraction of difluoromethane (CH2F2) and a mass fraction of at least one other component, wherein the mass fraction of carbon dioxide in the refrigerant mixture is 9 to 75 mass percent, the mass fraction of difluoromethane being up to 70 mass percent, the other component being 2,3,3,3-tetrafluoropropene (C3H2F4), the mass fraction of 2,3,3,3-tetrafluoropropene being up to 47 mass percent.

Abstract: A refrigerant for a cooling device comprising a cooling circuit with at least one heat exchanger, the refrigerant undergoing a phase transition in the heat exchanger, the refrigerant being a refrigerant mixture composed of a mass fraction of carbon dioxide (CO2), a mass fraction of pentafluoroethane (C2HF5) and a mass fraction of at least one other component, wherein the mass fraction of carbon dioxide in the refrigerant mixture is up to 60 mass percent, the mass fraction of pentafluoroethane being 11 to 72 mass percent, the other component being 2,3,3,3-tetrafluoropropene (C3H2F4), the mass fraction of 2,3,3,3-tetrafluoropropene being up to 51 mass percent.

Abstract: A refrigerant for a cooling device comprising a cooling circuit with at least one heat exchanger, the refrigerant undergoing a phase transition in the heat exchanger, the refrigerant being a refrigerant mixture composed of a mass fraction of carbon dioxide (CO2), a mass fraction of difluoromethane (CH2F2) and a mass fraction of at least one other component, wherein the mass fraction of carbon dioxide in the refrigerant mixture is 5 to 65 mass percent, the mass fraction of difluoromethane being up to 68 mass percent, the other component being trifluoroiodomethane (CF3I), fluoromethane (CH3F), ethane (C2H6), 1,1-difluoroethene (C2H2F2), ethene (C2H4), fluoroethene (C2H3F), ethyne (C2H2), propane (C3H8), propene (C3H6) and/or fluoroethane (CH2FCH3), said mass fraction being up to 55 mass percent.

Abstract: A refrigerant for a cooling device includes a cooling circuit with at least one heat exchanger, the refrigerant undergoing a phase transition in the heat exchanger, the refrigerant being a refrigerant mixture composed of a mass fraction of carbon dioxide, a mass fraction of pentafluoroethane, and a mass fraction of at least one other component, wherein the mass fraction of carbon dioxide in the refrigerant mixture is 20 to 74 mass percent, the mass fraction of pentafluoroethane being 8 to 65 mass percent, the other component being fluoromethane.

Abstract: A refrigerant for a cooling device including a cooling circuit with at least one heat exchanger, the refrigerant undergoing a phase transition in the heat exchanger, the refrigerant being a refrigerant mixture composed of a mass fraction of carbon dioxide, a mass fraction of pentafluoroethane, a mass fraction of difluoromethane and a mass fraction of at least one other component, wherein the mass fraction of carbon dioxide in the refrigerant mixture is 28 to 51 mass percent, the mass fraction of pentafluoroethane being 14.5 to 32 mass percent, the mass fraction of difluoromethane being 14.5 to 38 mass percent, the other component being fluoromethane.

Abstract: The disclosure relates to a method and a device for providing zeotropic refrigerants in which the refrigerant is formed from a refrigerant blend of at least two components, the components being added to a container in the ratio of their respective mass fractions to the refrigerant, and the refrigerant blend being formed in the container, wherein the temperature and/or the pressure in the container is set by means of a control device such that the refrigerant is present exclusively in the gas phase or exclusively in the liquid phase.

Abstract: Methods and compositions for the treatment of pulmonary disease using inhalation are provided. In particular, the present disclosure provides novel methods and compositions for treating pulmonary diseases such as asthma, bronchitis, COPD, emphysema, lung cancer, pneumonia and pulmonary edema. In addition, the present disclosure provides novel methods and compositions for treating complications associated with pulmonary disease such as corticosteroid resistance and pulmonary tissue destruction. The compositions of the present disclosure comprise corticosteroid resistance agents including but not limited to vitamin D, calcitriol and equivalents thereof. The compositions of the present disclosure also comprise alveolar development and maintenance agents including but not limited to vitamin A, ATRA and equivalents thereof. The present invention provides effective administration of therapeutic agents to specific airways of the lungs by utilizing controlled site delivery.