Patents by Inventor Murielle Marie VENIANT ELLISON

Murielle Marie VENIANT ELLISON has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • RNAI CONSTRUCTS AND METHODS FOR INHIBITING FAM13A EXPRESSION
    Publication number: 20240084301
    Abstract: The present application relates to compositions and methods for modulating expression of Family with Sequence Similarity 13 Member A (FAM13A) protein. In particular, the present application relates to nucleic acid-based therapeutics for reducing FAM13A gene expression via RNA interference and methods of using such nucleic acid-based therapeutics to reduce abdominal adiposity, reduce body weight, reduce fat mass, improve metabolic parameters including insulin resistance and non-alcoholic steatohepatitis (NASH), and reduce risk of myocardial infarction.
    Type: Application
    Filed: July 24, 2023
    Publication date: March 14, 2024
    Applicant: AMGEN INC.
    Inventors: Elizabeth Ann KILLION, Jerry Ryan HOLDER, Bryan MEADE, Justin K. MURRAY, Oliver R. HOMANN, Briana Renee GRIEGO, Murielle Marie VENIANT ELLISON
  • GROWTH DIFFERENTIATION FACTOR 15 FUSION PROTEINS
    Publication number: 20230143988
    Abstract: GDF15 molecules are provided herein. In some embodiments, the GDF15 molecule is a GDF15-Fc fusion, in which a GDF15 region is fused to an Fc region. In some embodiments, the GDF15 region is fused to the Fc region via a linker. Also, provided herein are methods for making and using GDF15 molecules.
    Type: Application
    Filed: April 8, 2019
    Publication date: May 11, 2023
    Applicant: AMGEN INC.
    Inventors: YuMei XIONG, Kenneth William WALKER, Murielle Marie VENIANT ELLISON
  • GROWTH DIFFERENTIATION FACTOR 15 COMBINATION THERAPY
    Publication number: 20220152154
    Abstract: The present disclosure provides combination therapy with GDF15 molecules. In some embodiments, the GDF15 molecule is a GDF15-Fc fusion, in which a GDF15 region is fused to an Fc region, optionally via a linker. In one embodiment, combination therapy comprises administration of a GDF15 molecule with a GLP-1R agonist. In another embodiment, combination therapy comprises administration of a GDF15 molecule with a GIPR antagonist.
    Type: Application
    Filed: March 6, 2020
    Publication date: May 19, 2022
    Applicant: AMGEN INC.
    Inventors: YuMei XIONG, Murielle Marie VENIANT ELLISON
  • GROWTH DIFFERENTIATION FACTOR 15 FUSION PROTEINS
    Publication number: 20220017584
    Abstract: GDF15 molecules are provided herein. In some embodiments, the GDF15 molecule is a GDF15-Fc fusion, in which a GDF15 region is fused to an Fc region. In some embodiments, the GDF15 region is fused to the Fc region via a linker. Also, provided herein are methods for making and using GDF15 molecules.
    Type: Application
    Filed: October 5, 2021
    Publication date: January 20, 2022
    Applicant: Amgen Inc.
    Inventors: YuMei XIONG, Kenneth William WALKER, Murielle Marie VENIANT ELLISON
  • Growth differentiation factor 15 fusion proteins
    Patent number: 11161889
    Abstract: GDF15 molecules are provided herein. In some embodiments, the GDF15 molecule is a GDF15-Fc fusion, in which a GDF15 region is fused to an Fc region. In some embodiments, the GDF15 region is fused to the Fc region via a linker. Also, provided herein are methods for making and using GDF15 molecules.
    Type: Grant
    Filed: January 14, 2021
    Date of Patent: November 2, 2021
    Assignee: AMGEN INC.
    Inventors: YuMei Xiong, Kenneth William Walker, Murielle Marie Veniant Ellison
  • GROWTH DIFFERENTIATION FACTOR 15 FUSION PROTEINS
    Publication number: 20210147500
    Abstract: GDF15 molecules are provided herein. In some embodiments, the GDF15 molecule is a GDF15-Fc fusion, in which a GDF15 region is fused to an Fc region. In some embodiments, the GDF15 region is fused to the Fc region via a linker. Also, provided herein are methods for making and using GDF15 molecules.
    Type: Application
    Filed: January 14, 2021
    Publication date: May 20, 2021
    Applicant: AMGEN INC.
    Inventors: YuMei XIONG, Kenneth William WALKER, Murielle Marie VENIANT ELLISON