Patents by Inventor Murray Kaplan

Murray Kaplan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20070133754
    Abstract: A system and method are provided for modifying an existing HDSL system to allow for remote access to performance monitoring information stored on each HDSL circuit card. This is accomplished by attaching a cable harness to an existing chassis. A cable harness containing a number of data lines equal to the number of circuit cards in the chassis is housed in a moveable bar which protects the harness and allows removal or insertion of HDSL circuit cards. Each data line attaches to a data port on the individual circuit cards, and the cable harness terminates to a multiplexer (shelf multiplexing unit). A system controller unit provides power and signaling to the shelf multiplexing unit, instructing the multiplexing unit to select an individual data line connected to an individual circuit card. Then utilizing a mutually agreed upon communications means, the system controller unit extends the HDSL data port connection to a remote location.
    Type: Application
    Filed: December 9, 2005
    Publication date: June 14, 2007
    Applicant: Telecom Assistance Group, Inc.
    Inventors: Murray Kaplan, Kenneth Kaplan, Paul Lorey
  • Patent number: 6455575
    Abstract: The present invention concerns antitumor compounds. More particularly, the invention provides novel taxane derivatives, pharmaceutical compositions thereof, and their use as antitumor agents.
    Type: Grant
    Filed: June 6, 1997
    Date of Patent: September 24, 2002
    Assignee: Bristol-Myers Squibb Company
    Inventors: Jerzy Golik, Dolatrai Vyas, John J. Wright, Henry Wong, John F. Kadow, John K. Thottathil, Wen-Sen Li, Murray A. Kaplan, Robert K. Perrone, Mark D. Wittman
  • Publication number: 20010023255
    Abstract: The present invention concerns antitumor compounds. More particularly, the invention provides novel taxane derivatives, pharmaceutical compositions thereof, and their use as antitumor agents.
    Type: Application
    Filed: June 6, 1997
    Publication date: September 20, 2001
    Inventors: JERZY GOLIK, DOLATRAI VYAS, JOHN J. WRIGHT, HENRY WONG, JOHN F. KADOW, JOHN K. THOTTATHIL, WEN-SEN LI, MURRAY A. KAPLAN, ROBERT K. PERRONE, MARK D. WITTMAN
  • Patent number: 6207650
    Abstract: Provided are very highly water soluble, stable, crystalline salts of 2′,3′-dideoxy-2′,3′-didehydrothymidine (“d4T”), 2′,3′-dideoxyinosine (“ddI”), and 2′,3′-dideoxy-2′-fluoroinosine (“F-ddI”). Such salts are useful as intermediates or as antiviral agents.
    Type: Grant
    Filed: December 6, 1991
    Date of Patent: March 27, 2001
    Assignee: Bristol-Myers Squibb Company
    Inventors: Joseph B. Bogardus, Murray A. Kaplan, Robert K. Perrone
  • Patent number: 5646176
    Abstract: The present invention concerns antitumor compounds. More particularly, the invention provides novel taxane derivatives, pharmaceutical compositions thereof, and their use as antitumor agents.
    Type: Grant
    Filed: May 19, 1995
    Date of Patent: July 8, 1997
    Assignee: Bristol-Myers Squibb Company
    Inventors: Jerzy Golik, Dolatrai Vyas, John J. Wright, Henry Wong, John F. Kadow, John K. Thottathil, Wen-Sen Li, Murray A. Kaplan, Robert K. Perrone, Mark D. Wittman
  • Patent number: 5608048
    Abstract: The present invention concerns a novel process using controlled cooling for obtaining d.sub.4 T polymorphic Form I from a mixture containing one or more of polymorphic Forms I, II and III. Compound d.sub.4 T has been approved for use in the treatment of AIDS.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: March 4, 1997
    Assignee: Bristol-Myers Squibb Company
    Inventors: Rajesh B. Gandhi, Joseph B. Bogardus, Peter M. Garofalo, Timothy R. Marr, Robert K. Perrone, Murray A. Kaplan
  • Patent number: 5455270
    Abstract: Solutions of carboplatin and other malonato platinum(II) antitumor agents are prepared containing stabilizing amounts of 1,1-cyclobutanedicarboxylic acid or salt at pH 4-8. The stabilizers inhibit unacceptable discoloration and precipitation. The solutions may also be stabilized by purging the carrier with air or oxygen and, optionally, blanketing the headspace with air or oxygen.
    Type: Grant
    Filed: August 11, 1993
    Date of Patent: October 3, 1995
    Assignee: Bristol-Myers Squibb Co.
    Inventors: Murray A. Kaplan, Lawan Phusanti, Robert K. Perrone, Scott R. Stenberg, Sheeram Agharkar, Joseph B. Bogardus
  • Patent number: 5401842
    Abstract: The present invention provides physical admixtures of a new crystalline dihydrochloride dihydrate salt of the cephalosporin antibiotic, cefepime with a pharmaceutically acceptable non-toxic organic or inorganic base. In particular, this invention provides physical admixtures having a temperature and moisture stable crystalline dihydrochloride dihydrate form of cefepime having a specific X-ray powder diffraction pattern as described herein.
    Type: Grant
    Filed: February 18, 1994
    Date of Patent: March 28, 1995
    Assignee: Bristol-Myers Squibb Company
    Inventors: Munir N. Nassar, Murray A. Kaplan
  • Patent number: 5391729
    Abstract: The present invention relates to a new crystalline dihydrochloride dihydrate salt of the cephalosporin antibiotic, cefepime. In particular, this invention provides a temperature and moisture stable crystalline dihydrochloride dihydrate form of cefepime having enhanced stability and a specific x-ray powder diffraction pattern as described herein.
    Type: Grant
    Filed: May 28, 1993
    Date of Patent: February 21, 1995
    Assignee: Bristol-Myers Squibb Company
    Inventors: Elizabeth A. Garofalo, Gary M. F. Lim, Murray A. Kaplan
  • Patent number: 5244891
    Abstract: Crystalline sulfuric, di-nitric, mono-hydrochloric, di-hydrochloric, and di- and sesqui-orthosphosphoric acid addition salts of 7-[.alpha.-(2-aminothiazol-4-yl)-.alpha.-(Z)-methoxyiminoacetamido]-3-[(1- methyl-1-pyrrolidinio)methyl]-3-cephem-4-carboxylate are stable even at elevated temperatures. The crystalline sulfuric acid addition salt is made by forming an admixture of (a) at least one molar equivalent of sulfuric acid with (b) zwitterion in an amount so as to be present in the admixture at a concentration of greater than 25 milligrams/ml, causing crystallization, separating the crystals, washing and drying. The crystalline monohydrochloride, dihydrochloride, and orthophosphate salts are prepared by dissolving the zwitterion in the appropriate amount of acid, causing crystallization by adding acetone and isolating the crystals. Physical admixtures of the salts with certain bases in proportions to give a pH ranging from about 3.
    Type: Grant
    Filed: May 22, 1992
    Date of Patent: September 14, 1993
    Assignee: Bristol-Myers Squibb Company
    Inventors: Murray A. Kaplan, Thomas W. Hudyma, Robert A. Lipper, Kun M. Shih, Susan D. Boettger
  • Patent number: 5196555
    Abstract: Platinum complexes are disclosed in which the formula is ##STR1## wherein A and B are each independently ammine or monodentate amine, or A and B taken together represent a bidentate amine, and A and B are coordinated to the platinum atom through their nitrogen atom; X and Y are each independently halogen; R' is C.sub.1 -C.sub.20 alkanoyl, aroyl, heteroaroyl, or a group selected from the group consisting of ##STR2## wherein u' is an integer from 1 to 5; and R" is hydrogen with the proviso that A, B, X, and Y are structually equatorial substituents with respect to OR'--Pt--OR". These platinum complexes show antitumor activity with relatively lower kidney or bone marrow toxicity.
    Type: Grant
    Filed: December 13, 1991
    Date of Patent: March 23, 1993
    Assignee: Bristol-Myers Squibb Company
    Inventors: Murray A. Kaplan, Robert K. Perrone, Joseph B. Bogardus, Kenneth J. Wilcox
  • Patent number: 5157718
    Abstract: An interface adapter is disclosed for utilization with a conventional toll operator position system having a keyboard, video display and controller which interface adapter interface with the TOPS position and external data bases and audio response units in a manner to permit the TOPS position to additionally perform such functions as directory assistance, order entry and line message delivery. The interface adapter includes first and second switching means to intercept the keyboard and video data paths of the TOPS position to isolate the controller and includes a control processor in communication with the external data bases and audio response units which is programmed to respond upon command from the keyboard to access the external data bases and audio response units as required and to communicate such data or audio response to the appropriate terminus.
    Type: Grant
    Filed: November 29, 1989
    Date of Patent: October 20, 1992
    Inventors: Murray Kaplan, Jeffrey R. Segal
  • Patent number: 5095011
    Abstract: A stable, amorphous, lyophilized dihydrochloride salt of 7-[.alpha.-(2-aminothiazol-4-yl)-.alpha.-(z)-methoxyiminoacetamido]-3-[(1- methyl-1-pyrrolidinium) methyl]-3-cephem-4-carboxylate is described. This lyophilized salt is more easily prepared than the crystalline counterpart and can be reconstituted in effective concentrations for intramuscular and intravenous injection utilizing suitable organic and inorganic bases to pH 3-7.0.
    Type: Grant
    Filed: December 20, 1990
    Date of Patent: March 10, 1992
    Assignee: Bristol-Myers Company
    Inventors: Murray A. Kaplan, Munir N. Nassar
  • Patent number: 5036010
    Abstract: A new antitumor antibiotic designated BMY-40800 is produced by fermentation of Streptomyces hygroscopicus ATCC 53653. The new compound inhibits the growth of tumors in experimental animals.
    Type: Grant
    Filed: April 26, 1990
    Date of Patent: July 30, 1991
    Assignee: Bristol-Myers Company
    Inventors: King S. Lam, Jacqueline Mattei, John E. Leet, James A. Matson, Koji Tomita, Murray A. Kaplan
  • Patent number: 5034397
    Abstract: This invention relates to novel compositions of the antitumor agent [4'-9-(acridinylamino) methanesulfon-m-anisidide], (m-AMSA). Acid salts of m-AMSA are dissolved in 1-methyl-2-pyrrolidinone to provide highly stable solutions. The solutions may be diluted with Sterile Water for Injection, U.S.P. to provide stable, non-precipitating solutions for intravenous use.
    Type: Grant
    Filed: December 12, 1985
    Date of Patent: July 23, 1991
    Assignee: Bristol-Myers Squibb Co.
    Inventors: Murray A. Kaplan, Robert A. Lipper
  • Patent number: 5023904
    Abstract: A direct telephone dialing ordering system and method is disclosed wherein a calling customer can order products and/or services from a given vendor without voice interchange. The system operates in a local Access and Transport Area (LATA) switching network which has Feature Group D services utilizing a predetermined dialing plan. The system is positioned within the LATA and is assigned a Feature Group D interexchange carrier number. In accordance with the dialing plan of the Feature Group D service, certain digits of the originating call are utilized to direct the call to the system within the LATA to a point of termination wherein the system appears as an interexchange carrier. The system is then free to utilize the remaining digits of the originating call for determination of variables such as vendor, product, grade and the like designations.
    Type: Grant
    Filed: October 12, 1989
    Date of Patent: June 11, 1991
    Assignee: Science Dynamics Corporation
    Inventors: Murray Kaplan, Robert W. Humes
  • Patent number: 4994451
    Abstract: Crystalline sulfuric, di-nitric, mono-hydrochloric, di-hydrochloric, and di- and sesqui-orthosphosphoric acid addition salts of 7-[.alpha.-(2-aminothiazol-4-yl)-.alpha.-(Z)-methoxyiminoacetamido]-3-[(1- methyl-1-pyrrolidinio)methyl]-3-cephem-4-carboxylate are stable even at elevated temperatures. The crystalline sulfuric acid addition salt is made by forming an admixture of (a) at least one molar equivalent of sulfuric acid with (b) zwitterion in an amount so as to be present in the admixture at a concentration of greater than 25 milligrams/ml, causing crystallization, separating the crystals, washing and drying. The crystalline monohydrochloride, dihydrochloride, and orthophosphate salts are prepared by dissolving the zwitterion in the appropriate amount of acid, causing crystallization by adding acetone and isolating the crystals. Physical admixtures of the salts with certain bases in proportions to give a pH ranging from about 3.
    Type: Grant
    Filed: December 11, 1989
    Date of Patent: February 19, 1991
    Assignee: Bristol-Myers Company
    Inventors: Murray A. Kaplan, Thomas W. Hudyma, Robert A. Lipper, Kun M. Shih, Susan D. Boettger
  • Patent number: 4994271
    Abstract: A new antitumor antibiotic designated BMY-40800 is produced by fermentation of Streptomyces hygroscopicus ATCC 53653. The new compound inhibits the growth of tumors in experimental animals.
    Type: Grant
    Filed: February 16, 1988
    Date of Patent: February 19, 1991
    Assignee: Bristol-Myers Company
    Inventors: Kin S. Lam, Jacqueline Mattei, John E. Leet, James A. Matson, Koji Tomita, Murray A. Kaplan
  • Patent number: 4946689
    Abstract: The invention relates to chemically stable, concentrated solutions of cis-diamminedinitratoplatinum which are pH-stabilized with nitric acid and are readily convertible to parenteral cisplatin solutions by addition of sources of chloride ion.
    Type: Grant
    Filed: November 23, 1988
    Date of Patent: August 7, 1990
    Assignee: Bristol-Myers Company
    Inventors: Murray A. Kaplan, Robert K. Perrone, Joseph B. Bogardus, Kenneth W. Douglas, Sr.
  • Patent number: 4927638
    Abstract: A solution of etoposide in dimethylisosorbide is disclosed. The solution is useful for filling gelatin capsules and may also be formulated into parenteral dosage forms.
    Type: Grant
    Filed: September 12, 1988
    Date of Patent: May 22, 1990
    Assignee: Bristol-Myers Company
    Inventors: Gururaj Bykadi, Murray A. Kaplan, Richard G. Corrao, Edward J. Bara, Ismat Ullah, Shreeram N. Agharkar