Patents by Inventor Murray S. Webb
Murray S. Webb has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20120003297Abstract: This invention provides methods for treating neoplasias in a mammal. In particular, the invention provides methods for treating various types of lymphomas, including relapsed forms of non-Hodgkin's Lymphoma. These methods involve the administration of liposome encapsulated vinca alkaloids, e.g., vincristine, to a mammal with a lymphoma.Type: ApplicationFiled: February 1, 2011Publication date: January 5, 2012Applicant: TALON THERAPEUTICS, INC.Inventors: Andreas SARRIS, Fernando CABANILLAS, Patricia M. LOGAN, Clive T.R. BURGE, James H. GOLDIE, Murray S. WEBB
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Patent number: 7887836Abstract: This invention provides methods for treating neoplasias in a mammal. In particular, the invention provides methods for treating various types of lymphomas, including relapsed forms of non-Hodgkin's Lymphoma. These methods involve the administration of liposome-encapsulated vinca alkaloids, e.g., vincristine, to a mammal with a lymphoma.Type: GrantFiled: March 7, 2008Date of Patent: February 15, 2011Assignees: Hana Biosciences, Inc., Board of Regents, The University of Texas SystemInventors: Andreas H. Sarris, Fernando Cabanillas, Patricia M. Logan, Clive T. R. Burge, James H. Goldie, Murray S. Webb
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Publication number: 20090041834Abstract: This invention provides methods for treating neoplasias in a mammal. In particular, the invention provides methods for treating various types of lymphomas, including relapsed forms of non-Hodgkin's Lymphoma. These methods involve the administration of liposome-encapsulated vinca alkaloids, e.g., vincristine, to a mammal with a lymphoma.Type: ApplicationFiled: March 7, 2008Publication date: February 12, 2009Applicants: Inex Pharmaceuticals Corporation, Board of Regents, The University of Texas SystemInventors: Andreas SARRIS, Fermando CABANILLAS, Patricia M. LOGAN, Clive T.R. BURGE, James H. GOLDIE, Murray S. WEBB
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Patent number: 7311924Abstract: This invention provides compositions and methods for treating neoplasias in a mammal. In particular, the invention provides liposome-encapsulated vinca alkaloids, e.g., vinorelbine, and methods of treating a mammal using such compositions.Type: GrantFiled: April 3, 2003Date of Patent: December 25, 2007Assignee: Hana Biosciences, Inc.Inventors: Andreas H Sarris, Fernando Cabanillas, Patricia M Logan, Clive T R Burge, James H Goldie, Murray S Webb, Thomas D Madden, Sean C Semple, Quet F Ahkong, Sandra K Klimuk
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Patent number: 7247316Abstract: This invention provides methods for treating neoplasias in a mammal. In particular, the invention provides methods for treating various types of lymphomas, including relapsed forms of non-Hodgkin's Lymphoma. These methods involve the administration of liposome-encapsulated vinca alkaloids, e.g., vincristine, to a mammal with a lymphoma.Type: GrantFiled: February 18, 2004Date of Patent: July 24, 2007Assignees: Board of Regents, The University of Texas System, Inex Pharmaceuticals CorporationInventors: Andreas H Sarris, Fernando Cabanillas, Patricia M Logan, Clive T R Burge, James H Goldie, Murray S Webb
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Patent number: 7244450Abstract: This invention provides methods for treating neoplasias in a mammal. In particular, the invention provides methods for treating various types of lymphomas, including relapsed forms of non-Hodgkin's Lymphoma. These methods involve the administration of liposome-encapsulated vinca alkaloids, e.g., vincristine, to a mammal with a lymphoma.Type: GrantFiled: December 4, 2003Date of Patent: July 17, 2007Assignees: Inex Pharmaceuticals Corporation, Board of Regents, The University of Texas SystemInventors: Andreas H. Sarris, Fernando Cabanillas, Patricia M. Logan, Clive T. R. Burge, James H. Goldie, Murray S. Webb
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Publication number: 20040253302Abstract: This invention provides methods for treating neoplasias in a mammal. In particular, the invention provides methods for treating various types of lymphomas, including relapsed forms of non-Hodgkin's Lymphoma. These methods involve the administration of liposome-encapsulated vinca alkaloids, e.g., vincristine, to a mammal with a lymphoma.Type: ApplicationFiled: December 4, 2003Publication date: December 16, 2004Applicants: Board of Regents, The University of Texas System, Inex Pharmaceuticals CorporationInventors: Andreas H. Sarris, Fernando Cabanillas, Patricia M. Logan, Clive T.R. Burge, James H. Goldie, Murray S. Webb
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Publication number: 20040228909Abstract: This invention provides methods for treating neoplasias in a mammal. In particular, the invention provides methods for treating various types of lymphomas, including relapsed forms of non-Hodgkin's Lymphoma. These methods involve the administration of liposome-encapsulated vinca alkaloids, e.g., vincristine, to a mammal with a lymphoma.Type: ApplicationFiled: February 18, 2004Publication date: November 18, 2004Applicants: Inex Pharmaceuticals Corporation, Board of Regents, The University of Texas SystemInventors: Andreas H. Sarris, Fernando Cabanillas, Patricia M. Logan, Clive T. R. Burge, James H. Goldie, Murray S. Webb
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Patent number: 6723338Abstract: This invention provides methods for treating neoplasias in a mammal. In particular, the invention provides methods for treating various types of lymphomas, including relapsed forms of non-Hodgkin's Lymphoma. These methods involve the administration of liposome-encapsulated vinca alkaloids, e.g., vincristine, to a mammal with a lymphoma.Type: GrantFiled: March 31, 2000Date of Patent: April 20, 2004Assignees: Inex Pharmaceuticals Corporation, Board of Regents, The University of Texas SystemInventors: Andreas H. Sarris, Fernando Cabanillas, Patricia M. Logan, Clive T. R. Burge, James H. Goldie, Murray S. Webb
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Publication number: 20040071768Abstract: This invention provides compositions and methods for treating neoplasias in a mammal. In particular, the invention provides liposome-encapsulated vinca alkaloids, e.g., vinorelbine, and methods of treating a mammal using such compositions.Type: ApplicationFiled: April 3, 2003Publication date: April 15, 2004Applicants: Inex Pharmaceuticals Corporation, The University of Texas, MD Anderson Cancer CenterInventors: Andreas H. Sarris, Fernando Cabanillas, Patricia M. Logan, Clive T. R. Burge, James H. Goldie, Murray S. Webb, Thomas D. Madden, Sean C. Semple, Quet F. Ahkong, Sandra K. Klimuk
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Publication number: 20030119768Abstract: It has now been discovered that oligonucleotides which tend to form multimeric aggregates have greater toxicity in the aggregate form than in monomeric form. Thus, administration of a therapeutic oligonucleotide that tends to form multimeric aggregates is suitably preceding by a treatment to convert substantially all of the therapeutic oligonucleotide to a monomeric form or to substantially prevent the formation of multimeric aggregates; and then administering the composition in which substantially all of the therapeutic oligonucleotide is in monomeric form to a mammal in need of therapy provided by the oligonucleotide. The composition can be treated by heating, preferably no more than 24 hours prior to administration, or using chemical species such as mannitol or sucrose which disrupt aggregates.Type: ApplicationFiled: October 29, 2001Publication date: June 26, 2003Inventors: Thomas D. Madden, Murray S. Webb
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Patent number: 5820873Abstract: The present invention provides a novel class of polyethylene glycol modified ceramide lipids. The lipids can be used to form liposomes optionally containing various biological agents or drugs, such as anti-cancer agents. In addition, methods of use for the liposomes are provided.Type: GrantFiled: June 7, 1995Date of Patent: October 13, 1998Assignee: The University of British ColumbiaInventors: Lewis S. L. Choi, Thomas D. Madden, Murray S. Webb
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Patent number: 5814335Abstract: Liposomal formulations having extended circulation time in vivo and increased drug retention are comprised of sphingomyelin and cholesterol and have an acidic intraliposomal pH. The formulations have enhanced stability and thus are used in methods which provide improved drug delivery and more effective treatment. The delivery of ciprofloxacin, and alkaloid drugs, particularly swainsonine, vincristine and vinblastine, is significantly improved.Type: GrantFiled: September 17, 1997Date of Patent: September 29, 1998Assignee: Inex Pharmaceuticals CorporationInventors: Murray S. Webb, Marcel B. Bally, Lawrence D. Mayer, James J. Miller, Paul G. Tardi
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Patent number: 5741516Abstract: Liposomal formulations having extended circulation time in vivo and increased drug retention are comprised of sphingomyelin and cholesterol and have an acidic intraliposomal pH. The formulations have enhanced stability and thus are used in methods which provide improved drug delivery and more effective treatment. The delivery of ciprofloxacin, and alkaloid drugs, particularly swainsonine, vincristine and vinblastine, is significantly improved.Type: GrantFiled: December 14, 1995Date of Patent: April 21, 1998Assignee: Inex Pharmaceuticals CorporationInventors: Murray S. Webb, Marcel B. Bally, Lawrence D. Mayer, James J. Miller, Paul G. Tardi
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Patent number: 5543152Abstract: Liposomal formulations having extended circulation time in vivo and increased drug retention are comprised of sphingomyelin and cholesterol and have an acidic intraliposomal pH. The formulations have enhanced stability and thus are used in methods which provide improved drug delivery and more effective treatment. The delivery of lipophilic drugs such as the vinca alkaloids, and particularly vincristine and vinblastine, to tumors is significantly improved.Type: GrantFiled: June 20, 1994Date of Patent: August 6, 1996Assignee: Inex Pharmaceuticals CorporationInventors: Murray S. Webb, Marcel B. Bally, Lawrence D. Mayer