Abstract: An audio infusion system and method are disclosed. A source audio track is separated into a plurality of audio tracks (e.g., instrumental, vocal, or mixes thereof) and the audio tracks are individually processed to generate a plurality of binaural beat tracks. At least one spatialized track is also generated by filtering the source audio track to provide a filtered track, generating one or more spatialization trajectories based on certain audio feature(s) of the source audio track (e.g., tempo) and a target end-state effect, and spatializing the filtered track using the spatialization trajectories. Other tracks may also be generated, such as one or more infrasonic tracks, ultrasonic tracks, enhanced bass tracks, and/or subharmonic tracks. The tracks may be played simultaneously or mixed for delivery to an end user device.

Abstract: A water channel is disclosed. The water channel has a channel body defining a flow passage having an entrance, an exit, and defining a flow direction from the entrance to the exit. Intake deflectors are positioned at the entrance and are angled away from the flow direction relative to the channel body and positioned to direct a flow of water into the entrance of the channel body. Outlet deflectors are positioned at the exit of the channel body and extend away from the exit of the channel body. The outlet deflectors are angled away from the flow direction relative to the channel body.

Abstract: The present invention relates to the recognition that inhibition of the base excision repair pathway is selectively lethal in cells which are deficient in HR dependent DNA DSB repair. Methods and means relating to the treatment of cancers which are deficient in HR dependent DNA DSB repair using inhibitors which target base excision repair components, such as PARP, is provided herein.

Abstract: A system and method for human motion detection and tracking are disclosed. In one embodiment, a smart device having an optical sensing instrument monitors a stage. Memory is accessible to a processor and communicatively coupled to the optical sensing instrument. The system captures an image frame from the optical sensing instrument. The image frame is then converted into a designated image frame format, which is provided to a pose estimator. A two-dimensional dataset is received from the pose estimator. The system then converts, using inverse kinematics, the two-dimensional dataset into a three-dimensional dataset, which includes time-independent static joint positions, and then calculates, using the three-dimensional dataset, the position of each of the respective plurality of body parts in the image frame.

Abstract: A system and method for human motion detection and tracking are disclosed. In one embodiment, a smart device having an optical sensing instrument monitors a stage. Memory is accessible to a processor and communicatively coupled to the optical sensing instrument. The system captures an image frame from the optical sensing instrument. The image frame is then converted into a designated image frame format, which is provided to a pose estimator. A two-dimensional dataset is received from the pose estimator. The system then converts, using inverse kinematics, the two-dimensional dataset into a three-dimensional dataset, which includes time-independent static joint positions, and then calculates, using the three-dimensional dataset, the position of each of the respective plurality of body parts in the image frame.

Abstract: A system and method for human motion detection and tracking are disclosed. In one embodiment, a smart device having an optical sensing instrument monitors a stage. Memory is accessible to a processor and communicatively coupled to the optical sensing instrument. The system captures an image frame from the optical sensing instrument. The image frame is then converted into a designated image frame format, which is provided to a pose estimator. A two-dimensional dataset is received from the pose estimator. The system then converts, using inverse kinematics, the two-dimensional dataset into a three-dimensional dataset, which includes time-independent static joint positions, and then calculates, using the three-dimensional dataset, the position of each of the respective plurality of body parts in the image frame.

Abstract: The invention relates to Pol? inhibitors for use in the treatment of a cancer associated with a Shieldin deficiency and to pharmaceutical compositions comprising said Pol? inhibitors.

Abstract: A system and method for human motion detection and tracking are disclosed. In one embodiment, a smart device having an optical sensing instrument monitors a stage. Memory is accessible to a processor and communicatively coupled to the optical sensing instrument. The system captures an image frame from the optical sensing instrument. The image frame is then converted into a designated image frame format, which is provided to a pose estimator. A two-dimensional dataset is received from the pose estimator. The system then converts, using inverse kinematics, the two-dimensional dataset into a three-dimensional dataset, which includes time-independent static joint positions, and then calculates, using the three-dimensional dataset, the position of each of the respective plurality of body parts in the image frame.

Abstract: A system and method for human motion detection and tracking are disclosed. In one embodiment, a smart device having an optical sensing instrument monitors a stage. Memory is accessible to a processor and communicatively coupled to the optical sensing instrument. The system captures an image frame from the optical sensing instrument. The image frame is then converted into a designated image frame format, which is provided to a pose estimator. A two-dimensional dataset is received from the pose estimator. The system then converts, using inverse kinematics, the two-dimensional dataset into a three-dimensional dataset, which includes time-independent static joint positions, and then calculates, using the three-dimensional dataset, the position of each of the respective plurality of body parts in the image frame.

Abstract: A system and method for human motion detection and tracking are disclosed. In one embodiment, a smart device having an optical sensing instrument monitors a stage. Memory is accessible to a processor and communicatively coupled to the optical sensing instrument. The system captures an image frame from the optical sensing instrument. The image frame is then converted into a designated image frame format, which is provided to a pose estimator. A two-dimensional dataset is received from the pose estimator. The system then converts, using inverse kinematics, the two-dimensional dataset into a three-dimensional dataset, which includes time-independent static joint positions, and then calculates, using the three-dimensional dataset, the position of each of the respective plurality of body parts in the image frame.

Abstract: The present invention relates to the recognition that inhibition of the base excision repair pathway is selectively lethal in cells which are deficient in HR dependent DNA DSB repair. Methods and means relating to the treatment of cancers which are deficient in HR dependent DNA DSB repair using inhibitors which target base excision repair components, such as PARP, is provided herein.

Abstract: A swimming pool skimmer comprises a buoyant skimmer body. The swimming pool skimmer further comprises an electrical power supply including a solar cell mounted to a topside of the skimmer body. A set of proximity sensors are operatively connected to the electrical power supply, and are mounted at a forward end of the skimmer body. The set of proximity sensors are configured to generate a signal in response to detecting an obstruction. A set of pump jets are operatively connected to both the electrical power supply and the set of proximity sensors. The set of pump jets are configured to activate in response to the signal from the set of proximity sensors, thereby rotating the swimming pool skimmer away from the obstruction.

Abstract: A swimming pool skimmer comprises a buoyant skimmer body. The swimming pool skimmer further comprises an electrical power supply including a solar cell mounted to a topside of the skimmer body. A set of proximity sensors are operatively connected to the electrical power supply, and are mounted at a forward end of the skimmer body. The set of proximity sensors are configured to generate a signal in response to detecting an obstruction. A set of pump jets are operatively connected to both the electrical power supply and the set of proximity sensors. The set of pump jets are configured to activate in response to the signal from the set of proximity sensors, thereby rotating the swimming pool skimmer away from the obstruction.

Abstract: A modular pipe and a method of installing the pipe uses a first pipe section positioned in end to end relation with a second pipe section, the first and second pipe sections being precast from a cement-based material, wherein each pipe section has an outer surface, a flow passage, a first end, and a second end. Each end has a connection profile, an axis, and an end face that is perpendicular to the axis. A collar surrounds and secures the connection between adjacent ends. The collar is constructed from a plurality of collar elements. Each collar element overlaps the pipe connection and engages the connection profile along a portion of the perimeter of each of the first end of the second pipe section and the second end of the first pipe section.

Abstract: There is provided a multi-sided culvert having a base section, a first side body, and a second side body. The first and second side bodies are engaged at the top of the culvert by a top engagement and supported by the base section. The base section engages the first side body by a first bottom engagement and the second side body by a second bottom engagement. The first part of the first bottom engagement has a first guide section and a first interlocking section, and the second part of the first bottom engagement has a second guide section and a second interlocking section. During installation the first and second guide sections guide the first and second interlocking sections into engagement, the first and second interlocking sections having tapered surfaces that, when engaged, permit upward and outward movement of the second part relative to the base.

Abstract: A swimming pool skimmer comprises a buoyant skimmer body. The swimming pool skimmer further comprises an electrical power supply including a solar cell mounted to a topside of the skimmer body. A set of proximity sensors are operatively connected to the electrical power supply, and are mounted at a forward end of the skimmer body. The set of proximity sensors are configured to generate a signal in response to detecting an obstruction. A set of pump jets are operatively connected to both the electrical power supply and the set of proximity sensors. The set of pump jets are configured to activate in response to the signal from the set of proximity sensors, thereby rotating the swimming pool skimmer away from the obstruction.

Abstract: A swimming pool skimmer comprises a buoyant skimmer body. The swimming pool skimmer further comprises an electrical power supply including a solar cell mounted to a topside of the skimmer body. A set of proximity sensors are operatively connected to the electrical power supply, and are mounted at a forward end of the skimmer body. The set of proximity sensors are configured to generate a signal in response to detecting an obstruction. A set of pump jets are operatively connected to both the electrical power supply and the set of proximity sensors. The set of pump jets are configured to activate in response to the signal from the set of proximity sensors, thereby rotating the swimming pool skimmer away from the obstruction.

Abstract: A swimming pool skimmer comprises a buoyant skimmer body. The swimming pool skimmer further comprises an electrical power supply including a solar cell mounted to a topside of the skimmer body. A set of proximity sensors are operatively connected to the electrical power supply, and are mounted at a forward end of the skimmer body. The set of proximity sensors are configured to generate a signal in response to detecting an obstruction. A set of pump jets are operatively connected to both the electrical power supply and the set of proximity sensors. The set of pump jets are configured to activate in response to the signal from the set of proximity sensors, thereby rotating the swimming pool skimmer away from the obstruction.