Abstract: Stable aqueous iodine/iodide/iodate germicidal compositions are provided which have relatively high quantities of free iodine therein and also substantially maintain the starting amounts of available and free iodine throughout a storage period of at least about three months. The compositions of the invention contain from about 0.01-1.4% by weight available iodine, from about 10-125 ppm free iodine, from about 0.005-0.5% by weight iodate ion, from about 0.1-15% by weight of iodine complexing agent, from about 0.004-0.5% by weight iodide ion, and have a pH of from about 2.0-4.5.

Abstract: Stable, aqueous complexor-iodine germicidal use compositions and concentrates adapted for application to animal or human skin are provided which have desirable complexor:iodine ratios of from about 2-4.5. The compositions and concentrates preferably include a polyethoxylated polyoxypropylene block copolymer (Poloxamer) as the complexing agent, wherein the polyoxypropylene moiety has an average molecular weight of at least 2600 and a polyoxyethylene content of from about 30%-75% by weight, in combination with from about 0.1%-5% by weight average available iodine on a nominal basis. Use of the defined class of Poloxamers allows formulation of both high and low temperature stable compositions and concentrates. Other ingredients such as emollients, buffering agents and viscosity improvers can also form a part of the use compositions and concentrates.

Abstract: Fatty acid sanitizer concentrates and diluted final solutions are provided which include individual amounts of germicidally effective fatty acid, hydrotrope, strong acid selected from the group consisting of phosphoric and sulphuric acid sufficient to lower the pH of the final solutions to about 1-5, and a concentrate stabilizing weak acid component selected from the group consisting of propionic, butyric and valeric acids and mixtures thereof. The concentrate stabilizing component enhances the room and low temperature phase stability of the concentrates, even when used at very low levels typically ranging from 3.5%-15% by weight. Preferably, the fatty acid is a mixture of nonanoic and decanoic acids, whereas the strong acid is selected from the group consisting of orthophosphoric, sulfuric and mixtures thereof. Alternately, stable concentrates and use dilutions can be provided using undecylenic acid, either alone or in combination with other fatty acids.

Abstract: Stable, aqueous detergent-iodine germicidal use compositions and concentrates adapted for application to animal or human skin are provided which have desirable detergent:iodine ratios of from about 2-4.5. The compositions and concentrates include a polyethoxylated polyoxypropylene block copolymer (poloxamer) as the complexing agent, wherein the polyoxypropylene moiety has an average molecular weight of at least 2600 and a polyoxyethylene content of from about 30%-75% by weight, in combination with from about 0.1%-5% by weight average available iodine on a nominal basis. Use of the defined class of poloxamers allows formulation of both high and low temperature stable compositions and concentrates. Other ingredients such as emollients, buffering agents and viscosity improvers can also form a part of the use compositions and concentrates.

Abstract: Fatty acid sanitizer concentrates and diluted final solutions are provided which include individual amounts of germicidally effective fatty acid, hydrotrope, strong acid sufficient to lower the pH of the final solutions to about 1-5, and a concentrate stabilizing weak acid component selected from the group consisting of propionic, butyric and valeric acids and mixtures thereof. The concentrate stabilizing component enhances the room and low temperature phase stability of the concentrates, even when used at very low levels typically ranging from 2.5%-15% by weight. Preferably, the fatty acid is a mixture of nonanoic and decanoic acids, whereas the strong acid is selected from the group consisting of orthophosphoric, sulfuric and mixtures thereof.

Abstract: New and improved germicidal iodine compositions are provided in which iodine levels, in the presence of organic adjuvants containing at least carbon, hydrogen and oxygen atoms, are maintained for extended periods of time in the presence of iodide, through the addition of iodate and control of pH within the range of pH 5-7.

Abstract: An improved iodine tincture is provided by incorporating therein a small amount, preferably about 0.25 to 2.5 parts, per part by weight of iodine, of povidone, 1-vinyl-2-pyrrolidone polymer. In these proportions , the povidone modified tincture of iodine exhibits markedly reduced tendency to burn or sensitize skin areas on which it dries, is stable, and at the same time retains the essential germicidal activity of unmodified tincture of iodine. The new products can be formulated directly, or as concentrates yielding the improved tincture upon extension with a prescribed amount of aqueous-ethanolic diluent.

Abstract: This invention relates to new and improved means for killing spores on instruments and the like utilizing the combination of glutaraldehyde and a detergent selected from the group consisting of nonionic, anionic and ampholytic surface active agents. The sporicidal kill activity of glutaraldehyde is enhanced by said detergents.

Abstract: The improved approach to the direct formulation of solid iodine carriers containing poly (N-vinyl-2-pyrrolidone) and an iodide, as disclosed in copending application Ser. No. 360,338, has been extended to the direct formulation of solid products containing, in addition to the PVP and iodide, compatible additives such as nonionic detergent, anionic detergent, elemental iodine and mixtures thereof, as well as to the direct formulation of other solid iodine carriers.

Abstract: Unique and novel phenolic synthetic detergent-disinfectant compositions are provided wherein the detergent component is an anionic detergent and the phenolic components thereof consist essentially of ortho phenylphenol in admixture with high activity and intermediate activity phenolics, the ratio of ortho phenylphenol to the high and intermediate activity phenolics being from about 4:1-1.1:1. When prepared as a use dilution, the ortho phenylphenol is present in an amount of at least about 450 p.p.m.When the ortho phenylphenol is employed only with the high activity phenolics, the preferred minimum amount of ortho phenylphenol should be at least about 600 p.p.m. and the ratio of the ortho phenylphenol to the high activity phenolics can then be from about 2.5:1-1.5:1 and, when used with intermediate activity phenolics at the same preferred minimum level, the ratio of the ortho phenylphenol to the intermediate activity phenolics can be from about 2.1:1-1.25:1.