Patents by Inventor Murugan R. Pandian

Murugan R. Pandian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and kits for detecting ITA in a biological sample
    Patent number: 8753825
    Abstract: Methods for detecting invasive trophoblast antigen (ITA) in biological samples comprise screening the samples for ITA using antibodies that bind to the ITA. The methods are useful to detect pregnancy, trophoblastic diseases, and Down's syndrome in fetuses of pregnant women. Some methods include screening the samples with a plurality of capture antibodies that specifically bind ITA. Chemiluminescent immunoassays are disclosed. The methods may be practiced with the diagnostic kits of the invention.
    Type: Grant
    Filed: July 17, 2012
    Date of Patent: June 17, 2014
    Assignee: Quest Diagnostics Investments Incorporated
    Inventors: Murugan R. Pandian, Julie Y. Yu
  • METHODS AND KITS FOR DETECTING ITA IN A BIOLOGICAL SAMPLE
    Publication number: 20130071861
    Abstract: Methods for detecting invasive trophoblast antigen (ITA) in biological samples comprise screening the samples for ITA using antibodies that bind to the ITA. The methods are useful to detect pregnancy, trophoblastic diseases, and Down's syndrome in fetuses of pregnant women. Some methods include screening the samples with a plurality of capture antibodies that specifically bind ITA. Chemiluminescent immunoassays are disclosed. The methods may be practiced with the diagnostic kits of the invention.
    Type: Application
    Filed: July 17, 2012
    Publication date: March 21, 2013
    Inventors: Murugan R. Pandian, Julie Y. Yu
  • Methods and kits for detecting ITA in a biological sample
    Patent number: 8227197
    Abstract: Methods for detecting invasive trophoblast antigen (ITA) in biological samples comprise screening the samples for ITA using antibodies that bind to the ITA. The methods are useful to detect pregnancy, trophoblastic diseases, and Down's syndrome in fetuses of pregnant women. Some methods include screening the samples with a plurality of capture antibodies that specifically bind ITA. Chemiluminescent immunoassays are disclosed. The methods may be practiced with the diagnostic kits of the invention.
    Type: Grant
    Filed: January 31, 2011
    Date of Patent: July 24, 2012
    Assignee: Quest Diagnostics Investments Incorporated
    Inventors: Murugan R. Pandian, Julie Y. Yu
  • METHODS AND KITS FOR DETECTING ITA IN A BIOLOGICAL SAMPLE
    Publication number: 20110189793
    Abstract: Methods for detecting invasive trophoblast antigen (ITA) in biological samples comprise screening the samples for ITA using antibodies that bind to the ITA. The methods are useful to detect pregnancy, trophoblastic diseases, and Down's syndrome in fetuses of pregnant women. Some methods include screening the samples with a plurality of capture antibodies that specifically bind ITA. Chemiluminescent immunoassays are disclosed. The methods may be practiced with the diagnostic kits of the invention.
    Type: Application
    Filed: January 31, 2011
    Publication date: August 4, 2011
    Inventors: Murugan R. Pandian, Julie Y. Yu
  • Methods and kits for detecting ITA in a biological sample
    Patent number: 7897362
    Abstract: Methods for detecting invasive trophoblast antigen (ITA) in biological samples comprise screening the samples for ITA using antibodies that bind to the ITA. The methods are useful to detect pregnancy, trophoblastic diseases, and Down's syndrome in fetuses of pregnant women. Some methods include screening the samples with a plurality of capture antibodies that specifically bind ITA. Chemiluminescent immunoassays are disclosed. The methods may be practiced with the diagnostic kits of the invention.
    Type: Grant
    Filed: October 15, 2008
    Date of Patent: March 1, 2011
    Assignee: Quest Diagnostics Investments Incorporated
    Inventors: Murugan R. Pandian, Julie Y. Lu
  • METHODS AND KITS FOR DETECTING ITA IN A BIOLOGICAL SAMPLE
    Publication number: 20090104624
    Abstract: Methods for detecting invasive trophoblast antigen (ITA) in biological samples comprise screening the samples for ITA using antibodies that bind to the ITA. The methods are useful to detect pregnancy, trophoblastic diseases, and Down's syndrome in fetuses of pregnant women. Some methods include screening the samples with a plurality of capture antibodies that specifically bind ITA. Chemiluminescent immunoassays are disclosed. The methods may be practiced with the diagnostic kits of the invention.
    Type: Application
    Filed: October 15, 2008
    Publication date: April 23, 2009
    Inventors: Murugan R. Pandian, Julie Y. Yu
  • Methods and kits for detecting ITA in a biological sample
    Patent number: 7439026
    Abstract: Methods for detecting invasive trophoblast antigen (ITA) in biological samples comprise screening the samples for ITA using antibodies that bind to the ITA. The methods are useful to detect pregnancy, trophoblastic diseases, and Down's syndrome in fetuses of pregnant women. Some methods include screening the samples with a plurality of capture antibodies that specifically bind ITA. Chemiluminescent immunoassays are disclosed. The methods may be practiced with the diagnostic kits of the invention.
    Type: Grant
    Filed: November 18, 2003
    Date of Patent: October 21, 2008
    Assignee: Quest Diagnostics Investments Incorporated
    Inventors: Murugan R. Pandian, Julie Y. Lu
  • Methods for detecting pregnancy
    Patent number: 6627457
    Abstract: Methods for detecting pregnancy in a woman comprise screening a biological sample of the woman for pregnancy markers. The methods of the invention include chemiluminescent assays for the pregnancy markers. The methods of the invention also comprise utilizing at least two capture antibodies that specifically bind different epitopes of the pregnancy marker in one assay. The methods of the invention permit detection of pregnancy within about 7 days after ovulation or implantation.
    Type: Grant
    Filed: July 30, 2001
    Date of Patent: September 30, 2003
    Assignee: Quest Diagnostics Investments Incorporated
    Inventors: Murugan R. Pandian, Julie Y. Lu
  • Methods for detecting Down's syndrome
    Publication number: 20030027234
    Abstract: Methods for detecting Down's syndrome in a fetus of a pregnant woman include screening serum samples obtained from the pregnant woman for abnormal levels of invasive trophoblast antigen. In particular, serum levels of invasive trophoblast antigen are compared to a standard. The methods can also be practiced using at least one additional marker.
    Type: Application
    Filed: July 30, 2001
    Publication date: February 6, 2003
    Inventors: Murugan R. Pandian, Julie Y. Lu
  • Methods for detecting pregnancy
    Publication number: 20030022381
    Abstract: Methods for detecting pregnancy in a woman comprise screening a biological sample of the woman for pregnancy markers. The methods of the invention include chemiluminescent assays for the pregnancy markers. The methods of the invention also comprise utilizing at least two capture antibodies that specifically bind different epitopes of the pregnancy marker in one assay. The methods of the invention permit detection of pregnancy within about 7 days after ovulation or implantation.
    Type: Application
    Filed: July 30, 2001
    Publication date: January 30, 2003
    Inventors: Murugan R. Pandian, Julie Y. Lu
  • Methods of determining an increased risk of a woman carrying a downs syndrome affected fetus by measuring an analyte in a biological sample
    Patent number: 6492178
    Abstract: There are provided methods for assaying biological specimens for one or more of leptin, prorenin or renin in order to provide predictive information about the likelihood of a woman carrying a Downs Syndrome affected fetus.
    Type: Grant
    Filed: August 8, 2000
    Date of Patent: December 10, 2002
    Assignee: Quest Diagnostic Investments, Incorporated
    Inventor: Murugan R. Pandian