Patents by Inventor Mutlu Erdogan

Mutlu Erdogan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Targeted in situ protein diversification by site directed DNA cleavage and repair
    Patent number: 11608570
    Abstract: The present invention relates to a method for producing a panel of cells (i.e. a cell library) expressing various different mutant variants of a protein of interest, wherein only one of said mutant variants is expressed per cell from a single gene copy. The present invention also relates to a method or cell library for identifying a mutant variant of a protein of interest having a different or modified biological activity as compared to the corresponding wild-type protein of interest. According to the present invention the identified mutant variant of a protein of interest may be applied for white biotechnology.
    Type: Grant
    Filed: July 31, 2017
    Date of Patent: March 21, 2023
    Assignee: Max-Planck-Gesellschaft zur Förderung der Wissenschaften E.V.
    Inventors: David Ng, Oliver Griesbeck, Mutlu Erdogan
  • TARGETED IN SITU PROTEIN DIVERSIFICATION BY SITE DIRECTED DNA CLEAVAGE AND REPAIR
    Publication number: 20190144853
    Abstract: The present invention relates to a method for producing a panel of cells (i.e. a cell library) expressing various different mutant variants of a protein of interest, wherein only one of said mutant variants is expressed per cell from a single gene copy. The present invention also relates to a method or cell library for identifying a mutant variant of a protein of interest having a different or modified biological activity as compared to the corresponding wild-type protein of interest. According to the present invention the identified mutant variant of a protein of interest may be applied for white biotechnology.
    Type: Application
    Filed: July 31, 2017
    Publication date: May 16, 2019
    Applicant: Max-Planck-Gesellschaft zur Förderung der Wissenschaften E.V.
    Inventors: David Ng, Oliver Griesbeck, Mutlu Erdogan