Abstract: Benzamide derivatives represented by the formula ##STR1## wherein X represents a lower alkoxy group; Y represents a mono- or di-lower alkylamino group; Z represents a halogen atom; R.sub.1 represents a lower alkyl group; and R.sub.2 represents a hydrogen atom or a halogen atom,and their pharmacologically acceptable nontoxic salts, which are strong central nervous system depressants, in particular strong antipsychotics.

Abstract: The compounds of this invention are strong central nervous system depressants, in particular strong antipsychotics.

Abstract: The compounds of this invention are strong central nervous system depressants, in particular strong antipsychotics.

Abstract: Pyrazine derivatives by the formula ##STR1## are disclosed. In the above formula, R.sup.1 and R.sup.2, which may be the same or different, each represents a hydrogen atom, a halogen atom, a hydroxy group, a lower alkoxy group, a phenyl lower alkoxy group, a phenoxy group, a mercapto group, a lower alkylthio group, a phenyl lower alkylthio group, a phenylthio group, an amino group, a substituted amino group, a lower alkyl group, a carbamoyl group or a sulfamoyl group; R.sup.3 represents a lower alkoxy group; R.sup.4, R.sup.5, and R.sup.6, which may be the same or different, each represents a hydrogen atom, a lower alkyl group, a cycloalkyl group, a phenyl lower alkyl group, or a phenyl group; and A represents a lower alkylene group; said R.sup.4 and A, said R.sup.5 and A, said R.sup.4 and R.sup.5, or said R.sup.5 and R.sup.