Abstract: The present invention relates to adult stem cells and a manufacturing method thereof. More specifically, the present invention relates to a recombinant expression vector containing a human hepatic growth factor (hHGF) gene, mesenchymal stem cells which are transformed thereby and express the hHGF, a manufacturing method of the mesenchymal stem cells, conditioned media (CM) which is obtained from the transformed cells and proliferates hepatocytes, a culture method of the mesenchymal stem cells producing the same, and the use of the transformed mesenchymal stem cells and their culture media as an agent for preventing and treating liver diseases. The manufacturing method of the mesenchymal stem cells comprises the steps of: isolating and culturing umbilical cord blood-derived mesenchymal stem cells; transforming the mesenchymal stem cells with the recombinant expression vector; and selecting the mesenchymal stem cells.

Abstract: The present invention relates to a method of improving wrinkle, whitening or anti-oxidation of a skin, and more specifically, to a method of improving wrinkle, whitening or anti-oxidation of a skin, comprising applying a cosmetic composition comprising a stem cell culture fluid as an active ingredient to the skin. Further, the present invention provides a method for preparing the cosmetic composition, comprising the steps of culturing stem cells and isolating the stem cells from the culture fluid.

Abstract: The present invention relates to a method for diagnosing colon cancer by detecting a colon cancer specific antigen, defensin ?6 from the blood of patient and a diagnostic kit for colon cancer comprising anti-defensin ?6 antibody. The diagnostic kit for colon cancer of present invention comprises: a solid support such as 96-well plate for ELISA, nitrocellulose membrane, polyvinylidene fluoride membrane, microplate, glass substrate, polystyrene substrate, silicone substrate or metal plate, on which anti-defensin ?6 antibody is immobilized; and, a means for detecting colon cancer specific antigen such as a primary antibody which specifically binds with an antigen conjugated with an antibody on a solid substrate and a secondary antibody-signal complex which specifically binds with the primary antibody. The diagnostic kit of the invention can diagnose colon cancer with the minute amount of patients' blood, which makes possible the easy and simple diagnosis of colon cancer.

Abstract: The present invention relates to a method for diagnosing colon cancer by detecting a colon cancer specific antigen, defensin ?6 from the blood of patient and a diagnostic kit for colon cancer comprising anti-defensin ?6 antibody. The diagnostic kit for colon cancer of present invention comprises: a solid support such as 96-well plate for ELISA, nitrocellulose membrane, polyvinylidene fluoride membrane, microplate, glass substrate, polystyrene substrate, silicone substrate or metal plate, on which anti-defensin ?6 antibody is immobilized; and, a means for detecting colon cancer specific antigen such as a primary antibody which specifically binds with an antigen conjugated with an antibody on a solid substrate and a secondary antibody-signal complex which specifically binds with the primary antibody. The diagnostic kit of the invention can diagnose colon cancer with the minute amount of patients' blood, which makes possible the easy and simple diagnosis of colon cancer.

Abstract: The present invention relates to a method for diagnosing colon cancer by detecting a colon cancer specific antigen, defensin ?6 from the blood of patient and a diagnostic kit for colon cancer comprising anti-defensin ?6 antibody, The diagnostic kit for colon cancer of present invention comprises, a solid support such as 96-well plate for ELISA, nitrocellulose membrane, polyvinylidene fluoride membrane, microplate, glass substrate, polystyrene substrate, silicone substrate or metalplate, on which anti-defensin ?6 antibody is immobilized; and, a means for detecting colon cancer specific antigen such as a primary antibody which specifically binds with an antigen conjugated with an antibody on a solid substrate and a secondary antibody-signal complex which specifically binds with the primary antibody. The diagnostic kit of the invention can diagnose colon cancer with the minute amount of patients' blood, which makes possible the easy and simple diagnosis of colon cancer.