Abstract: The invention is based upon the discovery that PAI-1 activity of a sample can be measured with sensitivity and correlation to in vivo activity without the use of standard curves. The assay determines the PAI-1 activity of a sample upon utilizing the second order rate equation for the reaction of PAI-1 and t-PA, as measured by their activities, in that sample.

Abstract: This invention provides an improved method for enhancing the activity of thrombolytic agents, including t-PA, scu-PA, tcu-PA, streptokinase, acylated plasminogen-streptokinase activator complex (APSAC), mixtures of these, and other activators of plasminogen. The enhancement method comprises supplementation of plasma plasminogen levels with deglycosylated forms of glu- and lys-plasminogen. Deglycosylated plasminogen refers herein to glu- or lys-plasminogen 2 having a single oligosaccharide chain at Thr.sub.345, plasminogens having a single oligosaccharide chain at Asn.sub.288, and unglycosylated forms of plasminogen. The work described herein shows that a less glycosylated form of plasminogen (glu-plasminogen 2) has a higher affinity for fibrin clots than a more glycosylated plasminogen (glu-plasminogen 1).

Abstract: A videophone system for providing videophone service within narrow band digital network, based on pipelined processing elements, includes source codec means coupled to the image bus, including numerous processing elements of which processing element has DSP (Digital Signal Processor) module, local memory module coupled to the DSP module, FIFO (First Input First Output) memory module coupled to the DSP module and the local memory module, and image bus interface module coupled to the DSP module and the local memory module and the image bus, wherein communications between the processor elements is performed via the pipeline and common memory means coupled to the VME bus and the image bus, for storing message data for synchronization and communication between the processing elements.