Patents by Inventor Myriam Golembo

Myriam Golembo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CHIMERIC POLYPEPTIDES, POLYNUCLEOTIDES ENCODING SAME, CELLS EXPRESSING SAME AND METHODS OF PRODUCING SAME
    Publication number: 20180291084
    Abstract: A plant produced chimeric polypeptide is provided. The plant produced chimeric polypeptide comprising: (i) a first domain which comprises a TNF Alpha binding domain of a TNF receptor, and (ii) a second domain which comprises an Fc domain of an immunoglobulin, wherein the first domain and the second domain are N-terminally to C-terminally respectively sequentially translationally fused and wherein the chimeric polypeptide specifically binds TNF Alpha.
    Type: Application
    Filed: June 13, 2018
    Publication date: October 11, 2018
    Applicant: Protalix Ltd.
    Inventors: Yoseph SHAALTIEL, Uri HANANIA, Tali KIZHNER, Tami ARIEL, Svetlana GINGIS-VELITSKI, Myriam GOLEMBO
  • Chimeric polypeptides, polynucleotides encoding same, cells expressing same and methods of producing same
    Patent number: 10000551
    Abstract: A plant produced chimeric polypeptide is provided. The plant produced chimeric polypeptide comprising: (i) a first domain which comprises a TNF Alpha binding domain of a TNF receptor, and (ii) a second domain which comprises an Fc domain of an immunoglobulin, wherein the first domain and the second domain are N-terminally to C-terminally respectively sequentially translationally fused and wherein the chimeric polypeptide specifically binds TNF Alpha.
    Type: Grant
    Filed: September 10, 2015
    Date of Patent: June 19, 2018
    Assignee: Protalix Ltd.
    Inventors: Yoseph Shaaltiel, Uri Hanania, Tali Kizhner, Tami Ariel, Svetlana Gingis-Velitski, Myriam Golembo
  • CHIMERIC POLYPEPTIDES, POLYNUCLEOTIDES ENCODING SAME, CELLS EXPRESSING SAME AND METHODS OF PRODUCING SAME
    Publication number: 20160075754
    Abstract: A plant produced chimeric polypeptide is provided. The plant produced chimeric polypeptide comprising: (i) a first domain which comprises a TNF Alpha binding domain of a TNF receptor, and (ii) a second domain which comprises an Fc domain of an immunoglobulin, wherein the first domain and the second domain are N-terminally to C-terminally respectively sequentially translationally fused and wherein the chimeric polypeptide specifically binds TNF Alpha.
    Type: Application
    Filed: September 10, 2015
    Publication date: March 17, 2016
    Inventors: Yoseph SHAALTIEL, Uri Hanania, Tali Kizhner, Tami Ariel, Svetlana Gingis-Velitski, Myriam Golembo
  • TREATMENT OF ACHONDROPLASIA WITH ENCAPSULATED CNP-SECRETING CELLS
    Publication number: 20140271868
    Abstract: The present invention relates to a method for the treatment of skeletal dysplasia by administering to a patient a composition comprising a therapeutically effective amount of at least one C-type natriuretic peptide (CNP).
    Type: Application
    Filed: April 17, 2014
    Publication date: September 18, 2014
    Applicant: HEPACORE LIMITED
    Inventors: Myriam Golembo, Avner Yayon
  • METHOD AND COMPOSITION FOR TREATMENT OF SKELETAL DYSPLASIAS
    Publication number: 20120328699
    Abstract: The present invention relates to a method for the treatment of skeletal dysplasia by administering to a patient a composition comprising a therapeutically effective amount of at least one C-type natriuretic peptide (CNP).
    Type: Application
    Filed: January 13, 2011
    Publication date: December 27, 2012
    Inventors: Myriam Golembo, Avner Yayon
  • METHOD AND COMPOSITION FOR TREATMENT OF SKELETAL DYSPLASIAS
    Publication number: 20100055150
    Abstract: The present invention relates to a method for the treatment of skeletal dysplasia by administering to a patient a composition comprising a therapeutically effective amount of at least one C-type natriuretic peptide (CNP).
    Type: Application
    Filed: November 4, 2009
    Publication date: March 4, 2010
    Inventors: Myriam Golembo, Avaer Yayon
  • METHOD AND COMPOSITION FOR TREATMENT OF SKELETAL DYSPLASIAS
    Publication number: 20080194682
    Abstract: The present invention discloses pharmaceutical compositions for the treatment of skeletal dysplasias, comprising as an active ingredient at least one natriuretic peptide. Unexpectedly, it has been shown that the natriuretic factors may be effective for bone elongation in situations of abnormal bone growth especially for achondroplasia. The effects of the natriuretic peptide may be further enhanced by prolonging its residence time or action at the target site.
    Type: Application
    Filed: August 17, 2007
    Publication date: August 14, 2008
    Applicant: ProChon Biotech Ltd.
    Inventors: Myriam Golembo, Avner Yayon
  • Method and composition for treatment of skeletal dysplasias
    Patent number: 7276481
    Abstract: The present invention discloses pharmaceutical compositions for the treatment of skeletal dysplasias, comprising as an active ingredient at least one natriuretic peptide. Unexpectedly, it has been shown that the natriuretic factors may be effective for bone elongation in situations of abnormal bone growth especially for achondroplasia. The effects of the natriuretic peptide may be further enhanced by prolonging its residence time or action at the target site.
    Type: Grant
    Filed: September 15, 2003
    Date of Patent: October 2, 2007
    Assignee: ProChon Biotech Ltd.
    Inventors: Myriam Golembo, Avner Yayon
  • Method and composition for treatment of skeletal dysplasias
    Publication number: 20040138134
    Abstract: The present invention discloses pharmaceutical compositions for the treatment of skeletal dysplasias, comprising as an active ingredient at least one natriuretic peptide. Unexpectedly, it has been shown that the natriuretic factors may be effective for bone elongation in situations of abnormal bone growth especially for achondroplasia. The effects of the natriuretic peptide may be further enhanced by prolonging its residence time or action at the target site.
    Type: Application
    Filed: September 15, 2003
    Publication date: July 15, 2004
    Inventors: Myriam Golembo, Avner Yayon