Patents by Inventor Myron L. Bender

Myron L. Bender has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4777250
    Abstract: Low molecular weight chymotrypsin analogs exhibiting the binding and catalytic groups of the real enzyme of the formula ##STR1## where D equals .alpha.-, .beta.- or .gamma.-cyclodextrin; P is X or (CH.sub.2).sub.n X, wherein n equals 0 to 2 and X equals S, NH, or 0; Q equals substituted phenyl with the carboxylate ion attached to the ortho position or equals (CH.sub.2).sub.n, wherein n equals 0 to 3; and R equals hydrogen --CH.sub.3 or --C.sub.2 H.sub.5.The enzyme models are useful as an analytical model mimicking the real enzyme, a stain remover, a laundry detergent additive, a food additive, and as a therapeutic agent for treating enzyme deficiencies.
    Type: Grant
    Filed: June 19, 1986
    Date of Patent: October 11, 1988
    Assignee: Northwestern University
    Inventors: Myron L. Bender, Valerian T. D'Souza
  • Patent number: 4774087
    Abstract: Microplasmin and microplasminogen are plasmin and plasminogen derivatives produced by the action of plasmin non plasmin/plasminogen at high pH. The action of plasmin at this pH cleaves the heavy (A) chain of plasmin at the Arg.sub.529 - Lys.sub.503 or Lys.sub.530 -Leu.sub.531 bond and promotes disulfide bond rearrangement, producing microplasmin or microplasminogen consisting of a 30 or 31 residue C-terminal peptide derived from the A chain bound through new disulfide bonds to the intact B-chain of plasmin or plasminogen. The resulting products are significantly reduced in size and retain native activity.
    Type: Grant
    Filed: August 14, 1987
    Date of Patent: September 27, 1988
    Assignee: Northwestern University
    Inventors: Hua-Lin Wu, Guey-Yueh Shi, Myron L. Bender