Patents by Inventor Myron Spector

Myron Spector has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20140094809
    Abstract: A method of creating a penetration with reduced sidewall compaction in a surface of a bone or articular joint. The method includes the steps of positioning a surgical instrument in contact with the surface, applying a longitudinal force to the surgical instrument causing the surgical instrument to penetrate the surface thereby creating a penetration with at least one sidewall, and retracting the surgical instrument and strategically scraping a portion of the surgical instrument against a portion of the at least one sidewall to remove compacted material from the penetration, thereby creating a small surgically created wound in the surface having reduced compaction at the margins to promote rapid vascular penetration, cellular migration, and faster healing with an enhanced histologically confirmed maturing tissue. The surgical defect can be round or slit-like.
    Type: Application
    Filed: December 4, 2013
    Publication date: April 3, 2014
    Inventors: Lanny L. Johnson, Myron Spector
  • Publication number: 20140094806
    Abstract: A surgical instrument whose cutting portion is a sharp miniature chisel or awl shape with a series of ridges along the course of the cutting tool. Each ridge has, on its proximal surface, a concave surface. Upon retraction, the instrument is pushed against the side of the defect, allowing the compacted bone on the walls to be captured in the concave recesses of the instrument. Existing instruments compact bone against the walls of the surgical defect rather than removing the compacted bone or tissue. The creation of a small surgically created wound in subchondral bone, absent the thickened compacted bone at the margins, responds with rapid vascular penetration and cellular migration and faster healing with an enhanced histologically confirmed maturing tissue. The surgical defect can be round or slit-like. The instrument allows a wide spectrum of angle of attack to create the surgical defect in the bone and/or articular surface.
    Type: Application
    Filed: October 2, 2012
    Publication date: April 3, 2014
    Inventors: Lanny Leo Johnson, Myron Spector
  • Patent number: 8084428
    Abstract: A method of repairing a meniscal tear of a subject includes providing a sheet of collagen membrane material having on one side thereof a smooth barrier face which inhibits cell adhesion thereon and inhibits passage of cells therethrough. The sheet has a fibrous face opposite the smooth barrier face, the fibrous face allowing cell growth thereon. The collagen is predominantly collagen I. The sheet of collagen membrane material is fixed over a meniscal tear so that the fibrous face is oriented toward the meniscal tear.
    Type: Grant
    Filed: September 1, 2006
    Date of Patent: December 27, 2011
    Assignee: Ed. Geistlich Soehne AG fuer Chemische Industrie
    Inventors: Myron Spector, Peter Geistlich, Lothar Schloesser, Roland Jakob, Jean-Francois Clemence
  • Publication number: 20100291173
    Abstract: A method of improving renal function in a mammal suffering from, or at risk of developing, at least partial renal failure or renal dysfunction, includes administering to renal tissue of the mammal, a combination comprising a non-viral vector comprising a non-viral particulate carrier which carries a therapeutically effective amount of genetic material capable of expressing a renal function-enhancing Osteogenic Protein-1/Bone Morphogenic Protein-7 (OP-1/BMP-7) polypeptide in the renal tissue.
    Type: Application
    Filed: September 4, 2007
    Publication date: November 18, 2010
    Applicant: ED. GEISTLICH SOEHNE AG FUER CHEMISCHE INDUSTRIE
    Inventors: Myron Spector, Peter Geistlich
  • Publication number: 20090186062
    Abstract: A method of repairing a meniscal tear of a subject includes providing a sheet of collagen membrane material having on one side thereof a smooth barrier face which inhibits cell adhesion thereon and inhibits passage of cells therethrough. The sheet has a fibrous face opposite the smooth barrier face, the fibrous face allowing cell growth thereon. The collagen is predominantly collagen I. The sheet of collagen membrane material is fixed over a meniscal tear so that the fibrous face is oriented toward the meniscal tear.
    Type: Application
    Filed: September 1, 2006
    Publication date: July 23, 2009
    Applicant: ED. GEISTLICH SOEHNE AG FUER CHEMISCHE INDUSTRIE
    Inventors: Myron Spector, Peter Geistlich, Lothar Schloesser, Roland Jakob, Jean-Francois Clemence
  • Publication number: 20060121609
    Abstract: This invention relates to gradient scaffolds, methods of producing the same, and methods of use thereof, in particular for applications in tissue engineering, repair and regeneration. The gradient scaffolding includes, inter-alia, scaffolds, which are varied in terms of their pore diameter, chemical composition, crosslink density, or combinations thereof, throughout the scaffolding.
    Type: Application
    Filed: September 21, 2005
    Publication date: June 8, 2006
    Inventors: Ioannis Yannas, Lorna Gibson, Fergal O'Brien, Brendan Harley, Ricardo Brau, Stephen Samouhos, Myron Spector
  • Publication number: 20040170664
    Abstract: Injured nerves are reconnected and regenerated by inserting injured nerve ends into a collagen tube having an outer compact smooth barrier surface preventing ingrowth of connective tissue, avoiding formation of scar tissue and allowing for unimpaired healing of injured nerves. The tube has an inner fibrous surface opposite the outer smooth barrier surface. The soft fibrous inner surface of the tube facilitates nerve growth promotion.
    Type: Application
    Filed: March 10, 2004
    Publication date: September 2, 2004
    Applicant: Ed. Geistlich Soehne AG
    Inventors: Myron Spector, Lothar Schloesser, Peter Geistlich
  • Patent number: 6710025
    Abstract: The present invention is directed to therapeutic methods that are based upon an ability to modulate cellular contraction. This is accomplished by administering agents that either inhibit or induce the activity of alpha-smooth muscle actin.
    Type: Grant
    Filed: May 23, 2000
    Date of Patent: March 23, 2004
    Assignee: The Brigham and Women's Hospital, Inc.
    Inventor: Myron Spector
  • Patent number: 6676969
    Abstract: A resorbable extracelluar matrix for reconstruction of cartilage tissue includes a purified collagen II derived from natural cartilage tissue from which non-collagen proteins have been removed.
    Type: Grant
    Filed: November 9, 2001
    Date of Patent: January 13, 2004
    Assignee: Ed. Geistlich Soehne AG fuer Chemische Industrie
    Inventors: Peter Geistlich, Myron Spector, Zdenek Eckmayer
  • Publication number: 20020048595
    Abstract: A resorbable extracelluar matrix for reconstruction of cartilage tissue includes a purified collagen II derived from natural cartilage tissue from which non-collagen proteins have been removed.
    Type: Application
    Filed: November 9, 2001
    Publication date: April 25, 2002
    Inventors: Peter Geistlich, Myron Spector, Zdenek Eckmayer
  • Patent number: 6352558
    Abstract: A method of promoting regeneration of surface cartilage of a joint includes the steps of forming punctures in a subchondral plate of an area of the joint to be treated, covering the puncture and the area to be treated with a chondrocyte-free patch made of a sheet of collagen membrane material without adding chondrocytes to the area to be treated, fixing the patch over the area to be treated, and allowing the area to be treated to regenerate cartilage without adding chondrocytes to the area to be treated.
    Type: Grant
    Filed: December 29, 1999
    Date of Patent: March 5, 2002
    Assignee: Ed. Geistlich Soehne AG fuer Chemische Industrie
    Inventor: Myron Spector
  • Publication number: 20020018799
    Abstract: Injured nerves are reconnected and regenerated by inserting injured nerve ends into a collagen tube having an outer compact smooth barrier surface preventing ingrowth of connective tissue, avoiding formation of scar tissue and allowing for unimpaired healing of injured nerves. The tube has an inner fibrous surface opposite the outer smooth barrier surface. The soft fibrous inner surface of the tube facilitates nerve growth promotion.
    Type: Application
    Filed: June 21, 2001
    Publication date: February 14, 2002
    Inventors: Myron Spector, Lothar Schloesser, Peter Geistlich
  • Patent number: 6326029
    Abstract: A resorbable extracellular matrix for reconstruction of cartilage tissue, the matrix being substantially free from non-native collagen, and including a purified collagen II material formed form natural cartilage and having fibers of native collagen II which are physiologically acceptable for implant into a mammalian body.
    Type: Grant
    Filed: November 10, 1997
    Date of Patent: December 4, 2001
    Assignee: Ed Geistlich Soehne AG fuer Chemische Industrie
    Inventors: Peter Geistlich, Myron Spector, Zdenek Eckmayer
  • Patent number: 6034296
    Abstract: An implantable self-powered sensing system for a bone fixation device, which includes a self-powered strain sensor mountable on or in a bone fixation device, is disclosed. The sensor is capable of measuring strain in the bone fixation device by generating a strain signal in response to stresses produced thereupon. The system also includes a telemetry unit powered by the generated strain signal and in communication with the sensor. The telemetry unit is activated by the sensor when the strain signal reaches a predetermined value and then transmits the strain signal from the sensor to an external receiver. The sensing system can also include a buffer unit in communication with the sensor and the telemetry unit for collecting and storing the strain signals for transmission by the telemetry unit as a cumulative strain measurement.
    Type: Grant
    Filed: December 4, 1997
    Date of Patent: March 7, 2000
    Inventors: Niell Elvin, Alex Elvin, Myron Spector
  • Patent number: 4882149
    Abstract: Pharmaceutical depot preparation for implantation into base tissue comprising natural bone mineral from which the naturally associated fat and bone-proteins have been removed whereby said bone is sterile and non-allergenic, said bone mineral having absorbed thereon and/or adsorbed therein one or more physiologically active substances. The physiologically active substance is advantageously an antibiotic or taurolidine or tauraltam or a protein or polypeptide assisting bone regeneration.
    Type: Grant
    Filed: September 21, 1988
    Date of Patent: November 21, 1989
    Assignee: Ed. Geistlich Sohne A.G. fur Chemische Industrie
    Inventor: Myron Spector
  • Patent number: 4773406
    Abstract: A bone fracture fixation device for fixation to a fractured bone is substantially free from resorbable materials and materials which soften on exposure to body fluids, and undergoes a gradual decrease in rigidity over the healing period of the fracture.
    Type: Grant
    Filed: July 2, 1987
    Date of Patent: September 27, 1988
    Assignee: Ed. Geistlich Sohne AG fur Chemische Industrie
    Inventors: Myron Spector, John D. Muzzy
  • Patent number: 4756862
    Abstract: Prosthetic devices, such as orthopedic, dental and maxillofacial prostheses, are provided which are composed of an inner load bearing, functional component and an outer foamed or sintered porous coating of selected bioengineering thermoplastics. The bioengineering thermoplastic coating is provided in regions where long-term bone fixation is desired by tissue ingrowth. The coatings offer substantial biomechanical advantages over any material system previously reported. Also provided, are anatomically shaped devices comprised totally of bioengineering thermoplastics with select porous areas; these devices include bone gap bridges, bone caps, and alveolar ridge augmentation implants.
    Type: Grant
    Filed: June 23, 1986
    Date of Patent: July 12, 1988
    Assignee: Amoco Corporation
    Inventors: Myron Spector, George T. Kwiatkowski, Walter H. Smarook, Michael J. Michno, Jr.
  • Patent number: 4362681
    Abstract: Prosthetic devices, such as orthopedic, dental and maxillofacial prostheses, are provided which are composed of an inner load bearing, functional component and an outer foamed or sintered porous coating of selected bioengineering thermoplastics. The bioengineering thermoplastic coating is provided in regions where long-term bone fixation is desired by tissue ingrowth. The coatings offer substantial biomechanical advantages over any material system previously reported. Also provided, are anatomically shaped devices comprised totally of bioengineering thermoplastics with select porous areas; these devices include bone gap bridges, bone caps, and alveolar ridge augmentation implants.
    Type: Grant
    Filed: January 18, 1980
    Date of Patent: December 7, 1982
    Assignee: Union Carbide Corporation
    Inventors: Myron Spector, George T. Kwiatkowski, Walter H. Smarook, Michael J. Michno, Jr.
  • Patent number: 4164794
    Abstract: Prosthetic devices, such as orthopedic, dental and maxillofacial prostheses, are provided which are composed of an inner load bearing, functional component and an outer foamed or sintered porous coating of selected bioengineering thermoplastics. The bioengineering thermoplastic coating is provided in regions where long-term bone fixation is desired by tissue ingrowth. The coatings offer substantial biomechanical advantages over any material system previously reported. Also provided, are anatomically shaped devices comprised totally of bioengineering thermoplastics with select porous areas; these devices include bone gap bridges, bone caps, and alveolar ridge augmentation implants.
    Type: Grant
    Filed: April 14, 1977
    Date of Patent: August 21, 1979
    Assignee: Union Carbide Corporation
    Inventors: Myron Spector, George T. Kwiatkowski, Walter H. Smarock, Michael J. Michno, Jr.