Patents by Inventor Mythili Ramachandran

Mythili Ramachandran has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9766252
    Abstract: An embodiment of the invention is a peptide comprising four domains, wherein domain I consists of thioctyl or monocytl, domain II consists of 2 to 3 positively charged amino acids selected from the group consisting of lysine and arginine, domain III consists of a dimeric ethylene unit; and domain IV comprises the peptide with SEQ ID No. 1 or a sequence having at least 90% identity to SEQ ID No. I. The peptide is preferably attached to a gold nanostructure, preferably a gold nanorod to provide an EFGR kit. An EFGR detection kit of the invention employs a gold nanostructure attached to a peptide sequence, the peptide sequence includes a binding sequence with an affinity toward EGFR, a ligand bound to gold atoms of the nanorod, a positively charged amino acid that maintains activity of the binding sequence, and a unit that increases hydrophilicity of the peptide sequence.
    Type: Grant
    Filed: March 13, 2013
    Date of Patent: September 19, 2017
    Assignee: The Curators of the University of Missouri
    Inventors: Raghuraman Kannan, Gerald Arthur, Charles W. Caldwell, Jr., Charles Caldwell, Mripen Chanda, Ajit Zambre, Mythili Ramachandran