Abstract: The present invention relates to a heteroaryl derivative compound and a use thereof. Since the heteroaryl derivative of the present invention exhibits excellent inhibitory activity against EGFR, the heteroaryl derivative can be usefully used as a therapeutic agent for EGFR-associated diseases.

Abstract: A glass-free microwave dielectric ceramic that can be sintered at low temperature is provided. The glass-free microwave dielectric ceramic composition includes (M1-x2+M?x2+)N4+B2O6 (wherein M and M? are different each other, each being one among Ba, Ca and Sr; N is one among Sn, Zr and Ti; and 0<x<1), M2+(N1-y4+N?y4+)B2O6 (wherein M is one among Ba, Ca and Sr; N and N? are different from each other, each being one among Sn, Zr and Ti; and 0<y<l), or (M1-x2+M?x2+)(N1-y4+)B2O6 (wherein M and M? are different from each other, each being one among Ba, Ca and Sr; N and N? are different from each other, each being one among Sn, Zr and Ti; 0<x<1; and 0<y<l). In addition, the glass-free microwave dielectric ceramic composition may further includes approximately 1 wt % to approximately 7 wt % of a sintering aid represented by a formula, 0.12CuO+0.88Bi2O3. As such, the glass-free microwave dielectric ceramic composition may be sintered at a low temperature at lowest 875° C.

Abstract: A glass-free microwave dielectric ceramic that can be sintered at low temperature, and a manufacturing method thereof are provided. The glass-free microwave dielectric ceramic composition includes a composition represented by a formula, M2+N4+B2O6, wherein M is one element of Ba, Ca and Sr, and N is one element of Sn, Zr and Ti. The M may be replaced by two elements of Ba, Ca and Sr different from each other, to form a composition represented by a formula, (M1-x2+Mx2+)N4+B2O6, wherein 0<x<1. The N may also be replaced by two elements of Sn, Zr and Ti different from each other, to form a composition represented by a formula, M2+(N1-y4+Ny4+)B2O6, wherein 0<y<1. Furthermore, it is also possible to replace both of the M and N to form a composition represented by a formula, (M1-x2+Mx2+)(N1-y4+Ny4+)B2O6, wherein 0<x<1 and 0<y<1.