Patents by Inventor Myung Hyun Sohn

Myung Hyun Sohn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL COMPOUND FOR INHIBITING HISTONE ACETYLTRANSFERASE P300 AND ANTI-FIBROSIS COMPOSITION COMPRISING SAME
    Publication number: 20230011131
    Abstract: The present invention relates to a novel compound, which enables additional hydrogen bonding with amino acids at specific positions of histone acetyltransferase (HAT) p300, through structure analysis of HAT p300. The novel compound of the present invention has a remarkably excellent effect of inhibiting HAT p300 activity and thus can be very effectively used in the prevention, alleviation, or treatment of fibrosis, which is a disease associated with activation of HAT p300.
    Type: Application
    Filed: August 5, 2020
    Publication date: January 12, 2023
    Inventors: Ho Guen Yoon, Myung Hyun Sohn, Soo Yeon Park, Jung Yeon Hong, Soo Yeon Lee, Youngjoo Kwon, Younghwa Na, Soo-Yeon Hwang, Jaeho Shin
  • NOVEL COMPOUND FOR INHIBITING HISTONE ACETYLTRANSFERASE P300 AND ANTIFIBROTIC COMPOSITION COMPRISING SAME
    Publication number: 20220194911
    Abstract: The present invention relates to a novel compound that enables formation of an additional hydrogen bond with a specific amino acid position in histone acetyltransferase (HAT) p300 through the structural analysis of the HAT p300. The novel compound of the present invention has a significantly excellent inhibitory effect on the activity of HAT p300 and can be used very effectively in the prevention, amelioration or treatment of diseases associated with the activation of HAT p300, such as fibrosis.
    Type: Application
    Filed: August 5, 2020
    Publication date: June 23, 2022
    Inventors: Ho Guen Yoon, Myung Hyun Sohn, Soo Yeon Park, Jung Yeon Hong, Soo Yeon Lee, Youngjoo Kwon, Younghwa Na, Soo-Yeon Hwang, Jaeho Shin