Patents by Inventor Myung-Ok Cho

Myung-Ok Cho has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Interferon polymer conjugates
    Patent number: 5711944
    Abstract: A process is disclosed for preparing long-acting alpha interferon-containing compositions. Alpha interferon is contacted with a relatively small molar excess of a substantially non-antigenic polymer in the presence of a surfactant to preserve bioactivity. Isolation of the desired conjugate species having optimal activity is also disclosed.
    Type: Grant
    Filed: November 10, 1994
    Date of Patent: January 27, 1998
    Assignee: Enzon, Inc.
    Inventors: Carl W. Gilbert, Myung-Ok Cho
  • Glycolipid enzyme-polymer conjugates
    Patent number: 5705153
    Abstract: Conjugates containing glucocerebrosidase and non-antigenic polymers such as polyethylene glycol are disclosed. The conjugates circulate for extended times and have prolonged activity in vivo when compared to unmodified enzymes. The conjugates are useful in the treatment of Gaucher's Disease and have improved enzyme activity at the pH ranges associated with lysosomal, arterial and capillary regions.
    Type: Grant
    Filed: October 23, 1996
    Date of Patent: January 6, 1998
    Assignee: The United States of America, as represented by The Department of Health and Human Services
    Inventors: Robert G. L. Shorr, Carl W. Gilbert, Brian M. Martin, Myung-Ok Cho, Edward J. Ginns
  • Glycolipid enzyme-polymer conjugates
    Patent number: 5620884
    Abstract: Conjugates containing glucocerebrosidase and non-antigenic polymers such as polyethylene glycol are disclosed. The conjugates circulate for extended times and have prolonged activity in vivo when compared to unmodified enzymes. The conjugates are useful in the treatment of Gaucher's Disease and have improved enzyme activity at the pH ranges associated with lysosomal, arterial and capillary regions.
    Type: Grant
    Filed: November 30, 1994
    Date of Patent: April 15, 1997
    Assignee: Enzon, Inc.
    Inventors: Robert G. L. Shorr, Myung-Ok Cho, Carl W. Gilbert, Edward J. Ginns, Brian M. Martin