Patents by Inventor Myung-ok P. Cho

Myung-ok P. Cho has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fractionation of polyalkylene oxide-conjugated hemoglobin solutions
    Patent number: 5478805
    Abstract: Hemoglobin-containing solutions containing polyalkyene oxide-conjugated hemoglobin having a molecular weight greater than about 85,000 daltons and a degree of substitution of at least five polyalkylene oxide conjugates per hemoglobin molecule are described that are not associated with hemoglobinuria in mammals. A method of simultaneously fractionating and purifying polyalkylene oxide-conjugated hemoglobins is also disclosed.
    Type: Grant
    Filed: November 3, 1993
    Date of Patent: December 26, 1995
    Assignee: Enzon, Inc.
    Inventors: Robert G. L. Shorr, Myung-Ok P. Cho, Kwang Nho
  • Fractionation of polyalkylene oxide-conjugated hemoglobin solutions
    Patent number: 5312808
    Abstract: Hemoglobin-containing solutions containing polyalkylene oxide-conjugated hemoglobin having a molecular weight greater than about 85,000 daltons and a degree of substitution of at least five polyalkylene oxide conjugates per hemoglobin molecule are described that are not associated with hemoglobinuria in mammals. A method of simultaneously fractionating and purifying polyalkylene oxide-conjugated hemoglobins is also disclosed.
    Type: Grant
    Filed: October 13, 1992
    Date of Patent: May 17, 1994
    Assignee: Enzon, Inc.
    Inventors: Robert G. L. Shorr, Myung-Ok P. Cho, Kwang Nho
  • Process for hemoglobin extraction and purification
    Patent number: 5264555
    Abstract: Methods are disclosed for separating hemoglobin from erythrocytes by contacting erythrocytes with a hypotonic buffer solution at a rate sufficient to render the release of hemoglobin from said erythrocytes without significant lysis. The hemoglobin is then separated from the erythrocytes. Methods are also disclosed for purifying hemoglobin solutions of DNA, endotoxins and phospholipids by contacting the hemoglobin solutions with an anion exchange medium.
    Type: Grant
    Filed: July 14, 1992
    Date of Patent: November 23, 1993
    Assignee: Enzon, Inc.
    Inventors: Robert G. L. Shorr, Kwang Nho, Myung-ok P. Cho, Chyi Lee, Barbara Czuba, Hariharan Shankar