Abstract: A tissue restoration composition in a colloidal phase, includes a copolymer in which a hydrophobic biocompatible polymer and a hydrophilic biocompatible polymer are polymerized and which is dispersed in water. The colloidal phase has increased viscosity by heating the copolymer dispersed in water. The colloidal phase has a viscosity, by the heating, of 20-200,000 cP.

Abstract: Disclosed are a composition for tissue repair treatment using a non-toxic biocompatible polymer and a method for manufacturing the same. The composition includes a copolymer in which a hydrophobic biocompatible polymer and a hydrophilic biocompatible polymer are polymerized, and having a colloidal phase in which the copolymer is dispersed in water. The method including: preparing a polymer by polymerizing a hydrophobic biocompatible polymer and a hydrophilic biocompatible polymer; and obtaining a colloidal solution by adding the polymer to water.

Abstract: Disclosed are a highly pure amphiphilic block copolymer including a hydrophobic polymer block of a poly(?-hydroxy acid), and a method for preparing the same. The method for preparing a highly pure amphiphilic block copolymer including a hydrophobic polymer block of a poly(?-hydroxy acid) includes removing ?-hydroxy acid, lactone monomers thereof, oligomers thereof and an organometal catalyst in polymerizing the amphiphilic block copolymer.

Abstract: Polylactic acid derivatives capable of forming micelles in an aqueous solution with a pH of 4 or above, having one terminal carboxyl group. The polylactic acid derivatives may be applied as a drug delivery system in various forms since poorly water soluble drugs can be entrapped inside the micelles.

Abstract: The present invention relates to a biodegradable branched polylactic acid derivative of formula 1, and preparation method and use thereof: <formula 1> 1-(R—X)n wherein each of X, R, I and n is defined as in the detailed description.

Abstract: Disclosed are a highly pure amphiphilic block copolymer including a hydrophobic polymer block of a poly(?-hydroxy acid), and a method for preparing the same. The method for preparing a highly pure amphiphilic block copolymer including a hydrophobic polymer block of a poly(?-hydroxy acid) includes removing ?-hydroxy acid, lactone monomers thereof, oligomers thereof and an organometal catalyst in polymerizing the amphiphilic block copolymer.

Abstract: The present invention relates to an ionic multi-block copolymer composition comprising tri-block copolymers having a polypropyleneoxide or polybutyleneoxide block positioned between two polyethyleneoxide blocks and the tri-block copolymers are connected through dicarboxylic acid linkages forming a multi-block copolymer having a weight average molecular weight of more than 40,000 Dalton. The higher weight average molecular weight enables the hydrolgel formed from the multi-block copolymer of the present invention to maintain its gel status for more than several days.

Abstract: There is provided in the present invention a composition for inhibiting adhesion comprising polymers that are dissolved in an aqueous solution and have temperature sensitivity showing a sol-gel phase transition dependant upon temperature, wherein the polymer solution in a sol state becomes a gel state by body temperature and is thus stably coated within tissues whereby it functions as a membrane inhibiting adhesion and as time lapses, it is degraded into low molecular weight surfactants and bio-degradable single molecular substances whereby they can be absorbed into body and the degraded products can bring about secondary adhesion inhibiting effects.

Abstract: The present invention relates to an amphiphilic block copolymer of a hydrophilic block and a hydrophobic block with a terminal hydroxyl group wherein the terminal hydroxyl group of the hydrophobic bock is substituted with a tocopherol or cholesterol group. It also relates to polymeric compositions capable of forming stable micelles in an aqueous solution, comprising the amphiphilic block copolymer and a polylactic acid derivative wherein one or more ends of the polylactic acid are covalently bound to at least one carboxyl group.

Abstract: The present invention relates to a biodegradable branched polylactic acid derivative of formula 1, and preparation method and use thereof: <formula 1> 1-(R—X)n wherein each of X, R, I and n is defined as in the detailed description.

Abstract: Polylactic acid derivatives capable of forming micelles in an aqueous solution with a pH of 4 or above, having one terminal carboxyl group. The polylactic acid derivatives may be applied as a drug delivery system in various forms since poorly water soluble drugs can be entrapped inside the micelles.