Abstract: The RGO (Reduced Graphene Oxide)-based bio sensor according to the present invention comprises: a source electrode and a drain electrode formed on a substrate; an RGO channel formed between the source electrode and the drain electrode; a PDMS (polydimethylsiloxane) chip supplying a reaction solution to the RGO channel; a passivation layer for sealing in order to prevent the reaction solution supplied through the PDMS chip from touching the source electrode and the drain electrode; and a gate electrode electrically connected to the reaction solution contacted to the RGO by being supplied through the PDMS chip. At this time, the passivation layer is formed with a SU-8 photoresistor, and the gate electrode is directly contacted to the reaction solution to thereby realize a liquid phase driving. The passivation layer is formed with SU-8 to allow supply of reaction solution through PDMS chip to be conveniently and stably realized. The operation is made possible at a gate voltage of ?1.0V˜1.

Abstract: A method for providing information relevant to the diagnosis of a neurodegenerative disorder. The method includes (i) obtaining a biological sample containing vesicles from a subject, (ii) measuring the level of amyloid beta in the biological sample using an antibody specific for the N-terminus of amyloid beta, and (iii) comparing the measured level of amyloid beta in the biological sample with the level of amyloid beta in a previously prepared control sample.

Abstract: A method for providing information relevant to the diagnosis of a neurodegenerative disorder. The method includes (i) obtaining a biological sample containing vesicles from a subject, (ii) measuring the level of amyloid beta in the biological sample using an antibody specific for the N-terminus of amyloid beta, and (iii) comparing the measured level of amyloid beta in the biological sample with the level of amyloid beta in a previously prepared control sample.

Abstract: The present disclosure relates to a cantilever sensor, and a biosensor having the same, wherein the cantilever sensor including a slit formed on a flat board and a cantilever formed by the slit, a first electrode formed on the cantilever, and a second electrode formed on the flat board countered to the first electrode about the slit, wherein the electrodes are formed on the cantilever sensor having the slit, whereby sensing can be conducted by an electric method, through which the sensor can be effectively miniaturized.

Abstract: The present disclosure relates to a cantilever sensor, and a biosensor having the same, wherein the cantilever sensor including a slit formed on a flat board and a cantilever formed by the slit, a first electrode formed on the cantilever, and a second electrode formed on the flat board countered to the first electrode about the slit, wherein the electrodes are formed on the cantilever sensor having the slit, whereby sensing can be conducted by an electric method, through which the sensor can be effectively miniaturized.