Patent number: 10590078
Abstract: The present invention relates to a compound having a blocking effect against sodium ion channels, particularly Nav1.7, a preparation method thereof and use thereof. The compound represented by the Formula 1 or a pharmaceutically acceptable salt, hydrate, solvate or isomer thereof can be effectively used in the prevention or treatment of pains, for example, acute pain, chronic pain, pain from nervous disease, postoperative pain, migraine, arthralgia, neuropathy, nerve injury, diabetic neuropathy, neuropathic disease, epilepsy, arrhythmia, myotonia, ataxia, multiple sclerosis, irritable bowel syndrome, urinary incontinence, visceral pain, depression, erythromelalgia, paroxysmal extreme pain disorder (PEPD).
Type:
Grant
Filed:
February 11, 2016
Date of Patent:
March 17, 2020
Assignee:
Daewoong Pharmaceutical Co., Ltd.
Inventors:
Ji Duck Kim, Hyung Geun Lee, Inwoo Kim, Sun Ah Jun, Myunggi Jung, Hyo Shin Kim