Publication number: 20200002377
Abstract: A compound has a formula (I) R1-Wm-Xn-AA1-AA2-AA3-AA4-AA5-AA6-(AA7)a-(AA8)b-Yp-Zq-R2, its stereoisomers and/or its cosmetically or pharmaceutically acceptable salts, wherein: AA1 is Glu or replaced by Asp, Gln or Asn, AA2 is Glu or replaced by Asp or Gln; AA3 is Met or replaced by Leu or Ile; AA4 is Gln or replaced by Glu, Asn or Asp; AA5 is Arg or replaced by Lys; AA6 is Arg or replaced by Lys or His; AA7 is Ala, Ser, Gly, Thr, Pro, Glu, Lys, or Val; AA8 is Asp, Glu, Asn, or Gln. In the compound, no more than two of AA1, AA2, AA3, AA4, AA5 and AA6 are replaced, a and b are 0 or 1; W, X, Y and Z are amino acids; m, n, p and q are each 0 or 1; and R1 and R2 are not amino acids. A method of skin treatment with the compound is also described.
Type:
Application
Filed:
November 30, 2017
Publication date:
January 2, 2020
Applicant:
LUBRIZOL ADVANCED MATERIALS, INC.
Inventors:
Wim Van Den Nest, Katalina RODRIGUEZ BIELSA, Olga LAPORTA, Nuria GARCIA SANZ, Nuria ALMIÑANA DOMÈNECH