Abstract: The present invention relates to an oral pharmaceutical composition for drugs with a high dosage regimen, specifically, ion exchange resins and bulk-forming laxatives. Said composition comprises the combination of a liquid oily component and a texturizing agent, giving the composition good organoleptic properties that allow taking drugs with a high dosage regimen without the usual problems associated with their poor palatability. The invention also relates to a method for preparing said composition and to the use thereof for the treatment of various pathologies. Furthermore, the invention also relates to an adduct formed between a polyol and an ion exchange resin, to a method for preparing it, and to the use thereof to improve resin palatability.

Abstract: The present invention relates to delayed-release methylphenidate tablets characterized in that they are provided with a release-controlling layer comprising a combination of an enteric polymer and a hydrophobic agent. These tablets have a release profile characterized in that the drug does not substantially start to release until approximately three hours after administration, completing it after approximately four hours after administration. This profile allows for the preparation of a modified-release dosage form of methylphenidate, combining the delayed-release tablet with an additional fraction of immediate-release methylphenidate. The dosage form thus obtained is suitable for treating attention deficit hyperactivity disorder (ADHD).

Abstract: The present invention relates to a solid pharmaceutical cation-exchange resin composition allowing the preparation of a stable resin suspension in an aqueous vehicle and the resin being easily resuspended in the case of sediment formation. Said composition comprises hydroxypropyl methylcellulose and pregelatinized starch as functional excipients. The invention also relates to a solid form for oral administration comprising the composition, to the use thereof for the preparation of oral solid forms, and to said composition for use in the treatment of hyperkalaemia.

Abstract: The present invention relates to an oral pharmaceutical composition for drugs with a high dosage regimen, specifically, ion exchange resins and bulk-forming laxatives. Said composition comprises the combination of a liquid oily component and a texturizing agent, giving the composition good organoleptic properties that allow taking drugs with a high dosage regimen without the usual problems associated with their poor palatability. The invention also relates to a method for preparing said composition and to the use thereof for the treatment of various pathologies. Furthermore, the invention also relates to an adduct formed between a polyol and an ion exchange resin, to a method for preparing it, and to the use thereof to improve resin palatability.

Abstract: The present invention relates to a solid pharmaceutical cation-exchange resin composition allowing the preparation of a stable resin suspension in an aqueous vehicle and the resin being easily resuspended in the case of sediment formation. Said composition comprises hydroxypropyl methylcellulose and pregelatinized starch as functional excipients. The invention also relates to a solid form for oral administration comprising the composition, to the use thereof for the preparation of oral solid forms, and to said composition for use in the treatment of hyperkalaemia.