Patents by Inventor N. Stephen Pollitt

N. Stephen Pollitt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Glycosylated Probnp
    Publication number: 20080312152
    Abstract: The present invention is directed to glycosylated proBNP and pharmaceutical compositions thereof. The present invention also relates to novel assays for measuring the total natriuretic activity that is present in a clinical blood sample.
    Type: Application
    Filed: October 16, 2006
    Publication date: December 18, 2008
    Inventors: N. Stephen Pollitt, Rodney A. Jue, Andrew A. Protter, Jessica O"Rear, Andrew Guzzetta, Ute Schellenberger
  • Vascular endothelial growth factor variants
    Patent number: 6887848
    Abstract: The invention is directed to a method of enhancing the biological activity of vascular endothelial growth factors (VEGF). The invention further concerns certain VEGF variants having enhanced biological activity, methods and means for preparing these variants, and pharmaceutical compositions comprising them. In a further aspect, the invention concerns methods of treatment using, and articles of manufacture containing such VEGF variants.
    Type: Grant
    Filed: October 10, 2002
    Date of Patent: May 3, 2005
    Assignee: Scios, Inc.
    Inventors: N. Stephen Pollitt, Judith A. Abraham
  • Vascular endothelial growth factor dimers
    Publication number: 20040241800
    Abstract: This invention concerns novel vascular endothelial growth factor (VEGF) dimers, compositions containing such dimers, processes for making such dimers, and methods for the treatment of various diseases by administering such dimers or compositions.
    Type: Application
    Filed: December 31, 2003
    Publication date: December 2, 2004
    Inventors: Rodney Alan Jue, Ute Schellenberger, Peter A. Stathis, Peter Isadore Adriaenssens, Judith A. Abraham, Patricia Ann Baldwin, N. Stephen Pollitt
  • Vascular endothelial growth factor variants
    Publication number: 20030096754
    Abstract: The invention is directed to a method of enhancing the biological activity of vascular endothelial growth factors (VEGF). The invention further concerns certain VEGF variants having enhanced biological activity, methods and means for preparing these variants, and pharmaceutical compositions comprising them. In a further aspect, the invention concerns methods of treatment using, and articles of manufacture containing such VEGF variants.
    Type: Application
    Filed: October 10, 2002
    Publication date: May 22, 2003
    Inventors: N. Stephen Pollitt, Judith A. Abraham
  • Vascular endothelial growth factor variants
    Patent number: 6475796
    Abstract: The invention is directed to a method of enhancing the biological activity of vascular endothelial growth factors (VEGF). The invention further concerns certain VEGF variants having enhanced biological activity, methods and means for preparing these variants, and pharmaceutical compositions comprising them. In a further aspect, the invention concerns methods of treatment using, and articles of manufacture containing such VEGF variants.
    Type: Grant
    Filed: May 18, 2000
    Date of Patent: November 5, 2002
    Assignee: Scios, Inc.
    Inventors: N. Stephen Pollitt, Judith A. Abraham
  • Nucleic acids sequence, stress-induced proteins and uses thereof
    Patent number: 6333191
    Abstract: A family of stimuli-induced in particular stress or cold-shock induced genes and proteins are disclosed which have conserved amino acid domains. Nucleic acid sequences of the genes and the promoters are also described. Various utilities of the promoters and of the proteins are disclosed.
    Type: Grant
    Filed: February 3, 1998
    Date of Patent: December 25, 2001
    Assignee: University of Medicine and Dentistry of New Jersey
    Inventors: Masayori Inouye, Pamela Jones, Jean-Pierre Etchegaray, Weining Jiang, N. Stephen Pollitt, Joel Goldstein
  • Method for producing a peptide with a pI above 8 or below 5
    Patent number: 6303340
    Abstract: A method is described for producing a peptide having a pI above 8 or below 5 wherein the peptide is expressed as a fusion protein in which it is linked to a fusion partner through an acid cleavage site. The peptide is released from the fusion partner by acid cleavage in the absence of chaotrope. The fusion partner and its acid cleavage products, if any, have a net charge sufficiently different from that of the desired peptide to allow isolation of the peptide by ion-exchange chromatography.
    Type: Grant
    Filed: July 8, 1999
    Date of Patent: October 16, 2001
    Assignee: Scios Inc.
    Inventors: N. Stephen Pollitt, Douglas I. Buckley, Peter A. Stathis, Taymar E. Hartman, Ziyang Zhong
  • Nucleic acids sequence, stress-induced proteins and uses thereof
    Patent number: 5714575
    Abstract: A family of stimuli-induced in particular stress or cold-shock induced genes and proteins are disclosed which have conserved amino acid domains. Nucleic acid sequences of the genes and the promoters are also described. Various utilities of the promoters and of the proteins are disclosed.
    Type: Grant
    Filed: March 1, 1994
    Date of Patent: February 3, 1998
    Assignee: The University of Medicine and Dentistry of New Jersey
    Inventors: Masayori Inouye, Pamela Jones, Jean-Pierre Etchegaray, Weining Jiang, N. Stephen Pollitt, Joel Goldstein