Patents by Inventor Na Gao

Na Gao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11946002
    Abstract: Provided is a method for treating an oil gas, which can realize high-efficiency separation for and recovery of gasoline components, C2, C3, and C4 components. The method first conducts separation of light hydrocarbon components from gasoline components, and then performs subsequent treatment on a stream rich in the light hydrocarbon components, during which it is no longer necessary to use gasoline to circularly absorb liquefied gas components, which significantly reduces the amount of gasoline to be circulated and reduces energy consumption throughout the separation process. Besides, in this method, impurities, such as H2S and mercaptans, in the stream rich in the light hydrocarbon components are removed first before the separation for the components. This ensures that impurities will not be carried to a downstream light hydrocarbon recovery section, thus avoiding corrosion issues caused by hydrogen sulfide in the light hydrocarbon recovery section.
    Type: Grant
    Filed: June 5, 2020
    Date of Patent: April 2, 2024
    Assignees: SINOPEC ENGINEERING INCORPORATION, SINOPEC ENGINEERING (GROUP) CO., LTD.
    Inventors: Mengqi Huang, Longhong Yu, Lei Wu, Shengyang Jiang, Yuwen Ding, Na Gao, Di Wu, Dan Duan
  • Patent number: 11913863
    Abstract: The present invention relates to a microplastic detection device and method based on a pyrolysis-mass spectrometry technology. The microplastic detection device based on a pyrolysis-mass spectrometry technology provided by the present invention is substantially a sealed gas path device system formed connected via pipelines. The device includes a working gas source, a pyrolysis device, a filter and a mass spectrometer which are connected in sequence. After a microplastic sample is placed into the pyrolysis device, the microplastic sample is decomposed in the pyrolysis device, and pyrolysis products from the microplastic sample driven by a carrier gas of the working gas source enter the mass spectrometer for detection and analysis after being filtered by the filter. Furthermore, the present invention provides a microplastic detection method based on a pyrolysis-mass spectrometry. The present invention is widely applied to the field of a microplastic detection technology.
    Type: Grant
    Filed: July 26, 2021
    Date of Patent: February 27, 2024
    Assignee: HARBIN INSTITUTE OF TECHNOLOGY, WEIHAI
    Inventors: Jie Jiang, Xiangnan Zhang, Na Li, Hengnan Zhang, Jing Gao
  • Publication number: 20240041918
    Abstract: A purified oligosaccharide compound having antithrombotic activity or a mixture of a homologous compound thereof and a pharmaceutically acceptable salt thereof, a preparation method for the mixture, a pharmaceutical composition containing the mixture, and uses thereof serving as an intrinsic factor X-enzyme (Xase) inhibitor in the preparation of drugs for preventing and/or treating thrombotic diseases.
    Type: Application
    Filed: September 28, 2023
    Publication date: February 8, 2024
    Inventors: Jinhua ZHAO, Zhenguo Li, Na Gao, Mingyi Wu, Yanming Chen, Longyan Zhao, Yongsheng Wu, Zi Li, Chuang Xiao, Shunliang Zheng, Zhiyuan Nan, Jianbo Zhou, Jianping Xu, Lutan Zhou, Yafang Guo, Hongbo Qin, Jikai Liu
  • Patent number: 11833169
    Abstract: A purified oligosaccharide compound having antithrombotic activity or a mixture of a homologous compound thereof and a pharmaceutically acceptable salt thereof, a preparation method for the mixture, a pharmaceutical composition containing the mixture, and uses thereof serving as an intrinsic factor X-enzyme (Xase) inhibitor in the preparation of drugs for preventing and/or treating thrombotic diseases.
    Type: Grant
    Filed: January 10, 2017
    Date of Patent: December 5, 2023
    Assignees: MUDANJIANG YOUBO PHARMACEUTICAL CO., LTD., JIUZHITANG CO., LTD.
    Inventors: Jinhua Zhao, Zhenguo Li, Na Gao, Mingyi Wu, Yanming Chen, Longyan Zhao, Yongsheng Wu, Zi Li, Chuang Xiao, Shunliang Zheng, Zhiyuan Nan, Jianbo Zhou, Jianping Xu, Lutan Zhou, Yafang Guo, Hongbo Qin, Jikai Liu
  • Publication number: 20230382871
    Abstract: Provided is the use of a CSF1R kinase inhibitor compound or a pharmaceutically acceptable salt thereof in the preparation of drugs for treating diseases related to the CSF1R kinase signal transduction pathway or drugs for regulating immunization.
    Type: Application
    Filed: September 22, 2021
    Publication date: November 30, 2023
    Inventors: Jian DING, Wenhu DUAN, Hua XIE, Meiyu GENG, Caixia WANG, Zhengsheng ZHAN, Na GAO, Yang ZHANG
  • Publication number: 20230277508
    Abstract: A use of a compound as a CYP2E1 inhibitor includes: using a compound shown in formula (I) or a salt thereof as an inhibitor to inhibit CYP2E1, where the compound or the salt thereof targets and binds to CYP2E1. The inhibitor can be used for the prevention and treatment of a tumor including liver cancer, glioma, ovarian cancer, lung cancer, bladder cancer, and gallbladder cancer. The inhibitor can also be used for the prevention and treatment of an inflammation-mediated disease (IMD) such as liver damage, fatty liver, hepatitis, liver fibrosis, pulmonary fibrosis, rheumatic and rheumatoid arthritis, sepsis, Alzheimer's disease (AD), ischemic stroke, Parkinson's disease (PD), hyperlipidemia, atherosclerosis (AS), coronary heart disease (CHD), and diabetes.
    Type: Application
    Filed: October 29, 2021
    Publication date: September 7, 2023
    Applicant: SHANGHAI LING XI BIOTECHNOLOGY DEVELOPMENT CO., LTD.
    Inventors: Hailing QIAO, Haiwei XU, Yan FANG, Na GAO, Qiang WEN, Shufeng LI
  • Publication number: 20230242507
    Abstract: A novel indazole compound, a preparation method therefor, and use thereof in the preparation of drugs for treating related diseases. Specifically disclosed are a compound of formula (II) and a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: June 28, 2021
    Publication date: August 3, 2023
    Inventors: Ke AN, Na GAO, Guoping HU, Jian LI, Shuhui CHEN, Deheng SUN
  • Publication number: 20230102081
    Abstract: Disclosed is a compound as shown in formula (I) or a pharmaceutically acceptable salt, a stereoisomer, an isotope derivative or a prodrug thereof. The compound has an excellent activity as a cyclin-dependent kinase 9 (CDK9) inhibitor for treating hyperproliferative diseases. The experimental research on in vitro inhibition of cell proliferation and in vivo suppression of tumors shows that such compounds have a relatively strong inhibitory effect on MV4;11 cells and in vivo tumor models, and have a good selectivity and a low toxicity and few side effects, thereby possessing a good clinical value as novel anti-tumor drugs.
    Type: Application
    Filed: December 9, 2020
    Publication date: March 30, 2023
    Applicant: CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd.
    Inventors: Zhenyu Wang, Yan Zhang, Yongzhao Mu, Jianqiao Guo, Hui An, Na Gao, Chaozai Zhang, Jia Wang
  • Publication number: 20210371760
    Abstract: Provided is a method for treating an oil gas, which can realize high-efficiency separation for and recovery of gasoline components, C2, C3, and C4 components. The method first conducts separation of light hydrocarbon components from gasoline components, and then performs subsequent treatment on a stream rich in the light hydrocarbon components, during which it is no longer necessary to use gasoline to circularly absorb liquefied gas components, which significantly reduces the amount of gasoline to be circulated and reduces energy consumption throughout the separation process. Besides, in this method, impurities, such as H2S and mercaptans, in the stream rich in the light hydrocarbon components are removed first before the separation for the components. This ensures that impurities will not be carried to a downstream light hydrocarbon recovery section, thus avoiding corrosion issues caused by hydrogen sulfide in the light hydrocarbon recovery section.
    Type: Application
    Filed: June 5, 2020
    Publication date: December 2, 2021
    Applicants: SINOPEC ENGINEERING INCORPORATION, SINOPEC ENGINEERING (GROUP) CO., LTD.
    Inventors: Mengqi Huang, Longhong Yu, Lei Wu, Shengyang Jiang, Yuwen Ding, Na Gao, Di Wu, Dan Duan
  • Publication number: 20200254003
    Abstract: A purified oligosaccharide compound having antithrombotic activity or a mixture of a homologous compound thereof and a pharmaceutically acceptable salt thereof, a preparation method for the mixture, a pharmaceutical composition containing the mixture, and uses thereof serving as an intrinsic factor X-enzyme (Xase) inhibitor in the preparation of drugs for preventing and/or treating thrombotic diseases.
    Type: Application
    Filed: January 10, 2017
    Publication date: August 13, 2020
    Inventors: Jinhua ZHAO, Zhenguo Li, Na Gao, Mingyi Wu, Yanming Chen, Longyan Zhao, Yongsheng Wu, Zi Li, Chuang Xiao, Shunliang Zheng, Zhiyuan Nan, Jianbo Zhou, Jianping Xu, Lutan Zhou, Yafang Guo, Hongbo Qin, Jikai Liu
  • Patent number: 10738394
    Abstract: The present invention discloses a molecular beam epitaxy under vector strong magnetic field and an in-situ characterization apparatus thereof. The apparatus mainly consists of an inverted T-shaped ultrahigh vacuum growth and characterization chamber with a compact structure and a strong magnet. The inverted T-shaped vacuum chamber portion, which disposed in the room-temperature chamber of the strong magnet, includes a compact epitaxial growth sample stage, a device capable of rotating angle between the growth and magnetic field directions, and an in-situ characterization apparatus. The portion disposed below the strong magnet includes a molecular beam source component such as evaporation source, plasma source etc., and a vacuum-pumping system.
    Type: Grant
    Filed: December 31, 2017
    Date of Patent: August 11, 2020
    Inventors: Junyong Kang, Chunmiao Zhang, Zhiming Wu, Ting Chen, Na Gao, Yaping Wu, Heng Li
  • Patent number: 10689463
    Abstract: Disclosed are a Fuc3S4S substituted oligoglycosaminoglycan with a weight-average molecular weight (Mw) of about 4.5-9 kD, a pharmaceutical composition containing the Fuc3S4S substituted oligoglycosaminoglycan, a preparation method thereof and a use thereof in preparing medicines for preventing and/or treating thrombotic diseases.
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: June 23, 2020
    Assignee: JIUZHITANG CO., LTD.
    Inventors: Jinhua Zhao, Jinxing He, Mingyi Wu, Zhiwen Liu, Na Gao, Longyan Zhao, Zi Li, Feng Lu, Li Xu, Chuang Xiao, Lian Yang, Jun Chen, Lutan Zhou, Wenlie Peng, Jikai Liu
  • Patent number: 10537601
    Abstract: The present invention provides a method of isolating at least one ingredient with anti-viral efficacy from Baphicacanthus cusia. The ingredient can be an alkaloid, a triterpenoid, a lignan, a phenylethanoid, a sesquiterpene lactone, or a flavonoid. Two new alkaloids are produced, which have not been previously reported. Moreover, the method isolates 12 compounds which could not or have not been previously isolated. A pharmaceutical composition includes the at least one ingredient and at least one pharmaceutical tolerable excipient. A method of treating a subject suffering from a viral disease includes administering at least one ingredient isolated from Baphicacanthus cusia.
    Type: Grant
    Filed: April 4, 2016
    Date of Patent: January 21, 2020
    Assignee: MACAU UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Jing-Rong Wang, Zhi-Hong Jiang, Qi-Tong Feng, Guo-Yuan Zhu, Wei-Na Gao, Zifeng Yang, Nanshan Zhong
  • Patent number: 10494452
    Abstract: A low-molecular-weight fucosylated glycosaminoglycan (aTFG) containing 2,5-anhydrated talose, alditol, glycosylamine or N-substituted glycosylamine monosaccharide composition thereof, preparation method thereof, pharmaceutical compositions containing the aTFG, and use thereof for preventing and/or treating thrombotic diseases are provided. The aTFG has potent anticoagulant activity targeting at intrinsic coagulation factor Xase, and inhibiting thrombogenesis, and therefore can be used as drugs for preventing and/or treating cardiovascular and cerebrovascular diseases.
    Type: Grant
    Filed: December 20, 2013
    Date of Patent: December 3, 2019
    Assignee: Jiuzhitang Co., Ltd.
    Inventors: Jinhua Zhao, Mingyi Wu, Na Gao, Zi Li, Sensen Lai, Longyan Zhao
  • Patent number: 10191050
    Abstract: This invention relates to novel rationale and methods for identifying human and primate taste-specific genes, including genes involved in salty taste perception, especially human salty taste perception, but also genes involved in sweet, bitter, umami, and sour taste perception, and genes involved in other taste cell or taste receptor related activities such as digestive function and digestive related diseases, taste cell turnover, immunoregulation of the oral and digestive tract, and metabolic regulation such as in diabetes and obesity, the genes identified using these methods, and assays for identifying taste modulators (enhancers or blockers) and potential therapeutics using these genes. These compounds have potential application in modulating (enhancing or blocking) taste perception, especially salty taste perception and as potential therapeutics.
    Type: Grant
    Filed: August 21, 2017
    Date of Patent: January 29, 2019
    Assignee: SENOMYX, INC.
    Inventors: Bryan Moyer, Albert Zlotnik, Peter Hevezi, Hortensia Soto, Dalia Kalabat, Min Lu, Na Gao, Evan Carl White
  • Patent number: 10185647
    Abstract: The supporting of debugging of failed vertex code on a test machine. This debugging is made possible even though the vertex code failed while on a remote processing node, and is but one of multiple, and potentially innumerable vertices that run in a distributed environment. This represents a vast technical improvement over prior ad hoc methods for trying to debug a large distributed application, since time is not wasted on vertices that operated properly, but rather debugging is focused on the problem vertex. Even reproducing the failure is a huge technical step forward.
    Type: Grant
    Filed: May 12, 2016
    Date of Patent: January 22, 2019
    Assignee: Microsoft Technology Licensing, LLC
    Inventors: Na Gao, Yifung Lin, Omid Afnan, Dian Zhang
  • Publication number: 20180179666
    Abstract: The present invention discloses a molecular beam epitaxy under vector strong magnetic field and an in-situ characterization apparatus thereof. The apparatus mainly consists of an inverted T-shaped ultrahigh vacuum growth and characterization chamber with a compact structure and a strong magnet. The inverted T-shaped vacuum chamber portion, which disposed in the room-temperature chamber of the strong magnet, includes a compact epitaxial growth sample stage, a device capable of rotating angle between the growth and magnetic field directions, and an in-situ characterization apparatus. The portion disposed below the strong magnet includes a molecular beam source component such as evaporation source, plasma source etc., and a vacuum-pumping system.
    Type: Application
    Filed: December 31, 2017
    Publication date: June 28, 2018
    Inventors: Junyong Kang, Chunmiao Zhang, Zhiming Wu, Ting Chen, Na Gao, Yaping Wu, Heng Li
  • Patent number: 9896517
    Abstract: Provided are a low-molecular-weight fucosylated glycosaminoglycan derivative (derivative of Low molecular weight Fucosylated Glycosaminoglycan, dLFG) having anticoagulant activity, a preparation method thereof, a pharmaceutical composition comprising dLFG or a pharmaceutically acceptable salt thereof, and the use of dLFG and pharmaceutical composition thereof in preparing medicine for treating thrombotic diseases.
    Type: Grant
    Filed: December 20, 2013
    Date of Patent: February 20, 2018
    Assignee: Jiuzhitang Co., Ltd.
    Inventors: Jinhua Zhao, Jikai Liu, Mingyi Wu, Na Gao, Feng Lu, Zi Li
  • Publication number: 20170356909
    Abstract: This invention relates to novel rationale and methods for identifying human and primate taste-specific genes, including genes involved in salty taste perception, especially human salty taste perception, but also genes involved in sweet, bitter, umami, and sour taste perception, and genes involved in other taste cell or taste receptor related activities such as digestive function and digestive related diseases, taste cell turnover, immunoregulation of the oral and digestive tract, and metabolic regulation such as in diabetes and obesity, the genes identified using these methods, and assays for identifying taste modulators (enhancers or blockers) and potential therapeutics using these genes. These compounds have potential application in modulating (enhancing or blocking) taste perception, especially salty taste perception and as potential therapeutics.
    Type: Application
    Filed: August 21, 2017
    Publication date: December 14, 2017
    Inventors: Bryan Moyer, Albert Zlotnik, Peter Hevezi, Hortensia Soto, Dalia Kalabat, Min Lu, Na Gao, Evan Carl White
  • Publication number: 20170281702
    Abstract: The present invention provides a method of isolating at least one ingredient with anti-viral efficacy from Baphicacanthus cusia. The ingredient can be an alkaloid, a triterpenoid, a lignan, a phenylethanoid, a sesquiterpene lactone, or a flavonoid. Two new alkaloids are produced, which have not been previously reported. Moreover, the method isolates 12 compounds which could not or have not been previously isolated. A pharmaceutical composition includes the at least one ingredient and at least one pharmaceutical tolerable excipient. A method of treating a subject suffering from a viral disease includes administering at least one ingredient isolated from Baphicacanthus cusia.
    Type: Application
    Filed: April 4, 2016
    Publication date: October 5, 2017
    Inventors: Jing-Rong Wang, Zhi-Hong Jiang, Qi-Tong Feng, Guo-Yuan Zhu, Wei-Na Gao, Zifeng Yang, Nanshan Zhong