Abstract: An anti-breakdown ion source discharge apparatus includes a discharge chamber, a coil support, an upper insulation fixing block, a discharge component and an ion source chamber. The discharge component includes a radio-frequency coil, a lower conductive connector and an upper conductive connector. The radio-frequency coil is fixed on a coil support base; the coil support base is clamped on an inner wall of the bottom of the ion source base; the coil support is along the circumference of the coil support base; the radio-frequency coil passes through the coil support; the upper conductive connector passes by the radio-frequency coil and the coil support base from the outside of the radio-frequency coil and extends into the bottom of the discharge chamber; and the upper insulation fixing block is sleeved over the upper conductive connector and is fixed on the inner wall of the bottom of the ion source chamber.

Abstract: The present application provides an organic-inorganic hybrid complex which can be used in a coating of a separator for a secondary battery, wherein the organic-inorganic hybrid complex is formed from basic units represented by formula (I) being periodically assembled in at least one spatial direction: [Lx-i?i][MaCb].Az (I), wherein a defect percentage expressed in i/x*100% is 1% to 30%. The present application further provides a coating composition comprising the organic-inorganic hybrid complex, a coating formed from the coating composition, a separator comprising the coating for a secondary battery, a secondary battery comprising the separator, a battery module, a battery pack and a device. By applying the organic-inorganic hybrid complex of the present application in a coating, the electrolyte infiltration of a separator for a secondary battery is improved while increasing the electrolyte retention rate, thereby improving the rate capability and cycling life of the secondary battery.

Abstract: A check valve for low pressure operating conditions includes: a valve cover, a valve body, and an upper diaphragm between the body and the cover. A first pressure cavity is provided on a lower surface of the valve cover and used for accommodating a backward direction medium, a second pressure cavity is machined on an upper surface of the valve body, within which an inflow passage and an outflow passage are provided, an inflow hole is machined from an inner wall of the inflow passage to a bottom face of the second pressure cavity, and a medium enters into the second pressure cavity from the inflow passage via the inflow hole, and applies upward pressure on the upper diaphragm. A backflow channel in communication with the first pressure cavity is machined on a side wall of the outflow passage.

Abstract: Described are techniques for predictive microservice activation. The techniques include training a machine learning model using a plurality of sequences of coordinates, where the plurality of sequences of coordinates are respectively based upon a corresponding plurality of series of vectors generated from historical usage data for an application and its associated microservices. The techniques further include inputting a new sequence of coordinates representing a series of application operations to the machine learning model. The techniques further include identifying a predicted microservice for future utilization based on an output vector generated by the machine learning model. The techniques further include activating the predicted microservice prior to the predicted microservice being called by the application.

Abstract: In an approach for smart test data workload generation, a processor receives a plurality of expected image frames for a user interface application to be tested. The plurality of expected image frames is pre-defined and represents a series of workflows and operations of the user interface application to be expected based on a design requirement. A processor calculates a first set of hash-values for each corresponding expected image frame. A processor samples the user interface application with a frequency to a plurality of testing image frames during a test run on the user interface application. A processor calculates a second set of hash-values for each sampled testing image frame. A processor compares the first set of hash-values to the second set of hash-values. A processor verifies that the second set of hash-values matches the first set of hash-values.

Abstract: An Internet-of-Things management and control system for an intelligent orchard includes a server, agricultural machinery equipment, an image acquisition apparatus disposed on the site, and various sensors. The agricultural machinery equipment, the image acquisition apparatus and the various sensors are in communication connection with the server. The server includes an orchard management subsystem and an information monitoring subsystem. The orchard management subsystem includes a fruit tree planting planning module, a task management module and various information management modules, and the information monitoring subsystem includes a meteorological environment monitoring module, a soil moisture monitoring module and a disease and pest monitoring module. According to the Internet-of-Things management and control system, all-round management for an orchard from planning to picking can be achieved.

Abstract: Provided in the present invention are a compound for inhibiting sodium glucose cotransporter 1, and a pharmaceutically acceptable salt and a stereoisomer of the compound. The compound is used for a pharmaceutical composition, and further provided is a method for preparing and using same, comprising the use of the drug or the composition in the preparation for the treatment and improvement of diabetes, cardiovascular and cerebrovascular diseases, weight loss, fatty liver, constipation, metabolism-related diseases and in the treatment of tumors.

Abstract: An Internet-of-Things management and control system for an intelligent orchard includes a server, agricultural machinery equipment, an image acquisition apparatus disposed on the site, and various sensors. The agricultural machinery equipment, the image acquisition apparatus and the various sensors are in communication connection with the server. The server includes an orchard management subsystem and an information monitoring subsystem. The orchard management subsystem includes a fruit tree planting planning module, a task management module and various information management modules, and the information monitoring subsystem includes a meteorological environment monitoring module, a soil moisture monitoring module and a disease and pest monitoring module. According to the Internet-of-Things management and control system, all-round management for an orchard from planning to picking can be achieved.

Abstract: Provided are a compound that inhibits sodium-glucose co-transporter 1, and a pharmaceutically acceptable salt and stereoisomer thereof. The compound is used in a pharmaceutical composition and preparation and usage methods, which comprise an application of a drug and composition thereof in the preparation for treating and improving diabetes, cardiovascular and cerebrovascular diseases, weight loss, fatty liver disease, constipation, metabolism-related diseases and tumor treatment.

Abstract: An aromatic compound protein inhibitor, a stereoisomer, a tautomer, or a pharmaceutically acceptable salt thereof, a method related to the preparation and use of the compound, a pharmaceutical composition comprising the compound, and a relevant cancer treatment method. The aromatic compound has selective and significant inhibitory activity on a protein, and has a wide application prospect in the field of tumor treatment.

Abstract: In an approach for smart test data workload generation, a processor receives a plurality of expected image frames for a user interface application to be tested. The plurality of expected image frames is pre-defined and represents a series of workflows and operations of the user interface application to be expected based on a design requirement. A processor calculates a first set of hash-values for each corresponding expected image frame. A processor samples the user interface application with a frequency to a plurality of testing image frames during a test run on the user interface application. A processor calculates a second set of hash-values for each sampled testing image frame. A processor compares the first set of hash-values to the second set of hash-values. A processor verifies that the second set of hash-values matches the first set of hash-values.

Abstract: One example charge pump is provided. The example charge pump includes a degeneration circuit, a charging current source transistor, a switch circuit and a discharging current source transistor. The charging current source transistor provides a charging current. The degeneration circuit is coupled between a first terminal of the charging current source transistor and a power supply terminal. The degeneration circuit degrades a first voltage corresponding to the power supply terminal to a second voltage. The switch circuit is coupled between a second terminal of the charging current source transistor and a load. The switch circuit controls a charging current output to the load.

Abstract: Disclosed is a targeted delivery system for a hydrophobic antitumor drug, referring to conjugates of E-selectin polypeptide ligand-polyethylene glycol-antitumor drug connected by different link bridges containing disulfide bonds. The synthesis of the conjugates, antitumor activity evaluation, the particle size and morphology characteristics of nanoparticles self-assembled by the conjugates in an aqueous solution, and the release of the antitumor drug in different conditions are comprised. The conjugates can actively target at vessels of a tumor site by the E-selectin peptide ligand, and can also self-assemble into nanoparticles in an aqueous solution, so as to be passively targeted at the tumor site by EPR effect.

Abstract: Described are techniques for predictive microservice activation. The techniques include training a machine learning model using a plurality of sequences of coordinates, where the plurality of sequences of coordinates are respectively based upon a corresponding plurality of series of vectors generated from historical usage data for an application and its associated microservices. The techniques further include inputting a new sequence of coordinates representing a series of application operations to the machine learning model. The techniques further include identifying a predicted microservice for future utilization based on an output vector generated by the machine learning model. The techniques further include activating the predicted microservice prior to the predicted microservice being called by the application.

Abstract: A charge pump (321), a phase-locked loop circuit (301), and a clock control apparatus are provided, related to the field of wireless communications technologies, to implement a high-speed and low-noise charge pump in the clock control apparatus. The charge pump includes a degeneration circuit (3210), a charging current source transistor (Mio 1), a switch circuit (3211) and a discharging current source transistor (Mc 2). The charging current source transistor is configured to provide a charging current. The degeneration circuit is coupled between a first terminal of the charging current source transistor and a power supply terminal. The degeneration circuit is configured to degrade a first voltage corresponding to the power supply terminal to a second voltage. The switch circuit is coupled between a second terminal of the charging current source transistor and a load. The switch circuit is configured to control a charging current output to the load.

Abstract: A hand-propelled power tool includes a main body, a handle assembly, a fixing plate assembly, and a walking assembly connected to the main body. The handle assembly includes a first connecting rod and a second connecting rod. The first connecting rod is provided with a first adjusting assembly. The second connecting rod is provided with a second adjusting assembly. The first adjusting assembly and the second adjusting assembly form a linkage by a connecting member. The first adjusting assembly and the second adjusting assembly include a first movement state and a second movement state. When in the first movement state, the connecting member can transmit a force between the first adjusting assembly and the second adjusting assembly. When in the second movement state, the connecting member does not transmit a force between the first adjusting assembly and the second adjusting assembly.

Abstract: The present disclosure relates to a reverse transcriptase and an application thereof. The reverse transcriptase has mutation sites such as R450H compared with the wild-type M-MLV reverse transcriptase. The reverse transcriptase has increased polymerase activity, improved thermal stability, and reduced RNase H activity.

Abstract: Disclosed herein is a preparation method and use of a surface double-modified human serum albumin as a tumor targeting nano drug carrier, wherein the targeting nano drug carrier includes human serum albumin (HSA), polyethylene glycol and E-selectin peptide ligand. The targeting nano drug carrier is formed by coupling the E-selectin peptide ligand and polyethylene glycol to the surface of HSA by thioether linker formed between the sulfhydryl group of E-selectin peptide ligand and activated HSA. The targeting nano drug carrier can encapsulate hydrophobic antitumor drugs and form nanoparticles with certain particle size after treatment, which can not only increase the solubility and stability of the hydrophobic antitumor drugs, but also can actively recognize and bind E-selectin which is highly expressed on activated endothelial cells at tumor site, competitively inhibit the interaction between E-selectin and tumor cells, and thus inhibit the adhesion and migration of tumor cells.

Abstract: A hand-propelled power tool includes a main body, a handle assembly, a fixing plate assembly, and a walking assembly connected to the main body. The handle assembly includes a first connecting rod and a second connecting rod. The first connecting rod is provided with a first adjusting assembly. The second connecting rod is provided with a second adjusting assembly. The first adjusting assembly and the second adjusting assembly form a linkage by a connecting member. The first adjusting assembly and the second adjusting assembly include a first movement state and a second movement state. When in the first movement state, the connecting member can transmit a force between the first adjusting assembly and the second adjusting assembly. When in the second movement state, the connecting member does not transmit a force between the first adjusting assembly and the second adjusting assembly.

Abstract: Disclosed is a targeted delivery system for a hydrophobic antitumor drug, referring to conjugates of E-selectin polypeptide ligand-polyethylene glycol-antitumor drug connected by different link bridges containing disulfide bonds. The synthesis of the conjugates, antitumor activity evaluation, the particle size and morphology characteristics of nanoparticles self-assembled by the conjugates in an aqueous solution, and the release of the antitumor drug in different conditions are comprised. The conjugates can actively target at vessels of a tumor site by the E-selectin peptide ligand, and can also self-assemble into nanoparticles in an aqueous solution, so as to be passively targeted at the tumor site by EPR effect.