Patents by Inventor Na Guo

Na Guo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220297168
    Abstract: The present invention provides a rotatable faraday cleaning apparatus and a plasma processing system, said apparatus comprising a cavity cover, a motor, an eccentric wheel, a long-petalled assembly, a coupling window, a gas intake nozzle, a connecting rod, a short-petalled assembly, a first sector-shaped conductor, and a second sector-shaped conductor; the cavity cover is assembled on a reactor cavity main body, the coupling window is mounted on the cavity cover, the gas intake nozzle is provided on the coupling window, the first sector-shaped conductor is assembled on the gas intake nozzle, the second sector-shaped conductor is assembled on the gas intake nozzle, the long-petalled assembly is assembled on the gas intake nozzle, the short-petalled assembly is assembled on the gas intake nozzle, the connecting rod is assembled on the long-petalled assembly, the eccentric wheel is assembled on the connecting rod, and the motor is mounted on the eccentric wheel.
    Type: Application
    Filed: February 28, 2020
    Publication date: September 22, 2022
    Applicant: JIANGSU LEUVEN INSTRUMENTS CO., LTD
    Inventors: Haiyang LIU, Dongdong HU, Xiaobo LIU, Na LI, Shiran CHENG, Song GUO, Zhihao WU, Kaidong XU
  • Patent number: 11413281
    Abstract: Disclosed is a targeted delivery system for a hydrophobic antitumor drug, referring to conjugates of E-selectin polypeptide ligand-polyethylene glycol-antitumor drug connected by different link bridges containing disulfide bonds. The synthesis of the conjugates, antitumor activity evaluation, the particle size and morphology characteristics of nanoparticles self-assembled by the conjugates in an aqueous solution, and the release of the antitumor drug in different conditions are comprised. The conjugates can actively target at vessels of a tumor site by the E-selectin peptide ligand, and can also self-assemble into nanoparticles in an aqueous solution, so as to be passively targeted at the tumor site by EPR effect.
    Type: Grant
    Filed: July 21, 2016
    Date of Patent: August 16, 2022
    Assignee: TIANJIN UNIVERSITY OF SCIENCE & TECHNOLOGY
    Inventors: Peng Yu, Na Guo, Dong Wang, Yuou Teng, Tiantian Hao, Huan Liu, Tianle Zhang, Xiuzhuan Shang
  • Publication number: 20220254604
    Abstract: Disclosed in the present application is an inductively coupled plasma treatment system. Said system switches the connection between a radio frequency coil and a faraday shielding device by means of a switch switching radio frequency power. When a radio frequency power supply is connected to the radio frequency coil by means of a matched network, the radio frequency power is coupled into the radio frequency coil to perform plasma treatment process. When a radio frequency power supply is connected to a faraday shielding device by means of a matched network, the radio frequency power is coupled into the faraday shielding device to perform cleaning process on a dielectric window and an inner wall of a plasma treatment cavity.
    Type: Application
    Filed: February 26, 2020
    Publication date: August 11, 2022
    Applicant: JIANGSU LEUVEN INSTRUMENTS CO. LTD
    Inventors: Haiyang LIU, Xiaobo LIU, Xuedong LI, Na LI, Shiran CHENG, Song GUO, Dongdong HU, Kaidong XU
  • Publication number: 20220254615
    Abstract: The present invention provides a device for blocking plasma backflow in a process chamber to protect an air inlet structure, comprising an air inlet nozzle tightly connected to an air inlet flange. The inner cavity of the air inlet nozzle is provided with an air inlet guide body, wherein the air inlet guide body has an upper structure, a middle structure, and a lower structure, the upper, middle, and lower structures are an integrated structure, the upper, middle, and lower structures are all cylindrical, the cross-sectional diameter of the upper structure is smaller than that of the middle structure, a gas gathering area is arranged between the middle structure and the lower structure, and the middle structure and the lower structure are connected by the gas gathering area.
    Type: Application
    Filed: February 29, 2020
    Publication date: August 11, 2022
    Applicant: JIANGSU LEUVEN INSTRUMENTS CO. LTD
    Inventors: Na LI, Dongdong HU, Xiaobo LIU, Haiyang LIU, Shiran CHENG, Song GUO, Zhihao WU, Kaidong XU
  • Publication number: 20220226260
    Abstract: An application of honokiol and magnolol in preparation of an MCR-1 enzyme inhibitor, provides a novel medical application of the honokiol and the magnolol in the preparation of the MCR-1 enzyme inhibitor. The honokiol and the magnolol can inhibit the activity of MCR-1 enzymes and restore the bactericidal activity of polymyxin to MCR-1 Enterobacteriaceae. In vivo experiments, the honokiol and the magnolol combined with polymyxin have a good therapeutic effect on bacterial infection expressing MCR-1, especially infections caused by MCR-1 positive Enterobacteriaceae, and have wide medical applications.
    Type: Application
    Filed: April 5, 2022
    Publication date: July 21, 2022
    Inventors: XUMING DENG, YAN GUO, JIANFENG WANG, YONGLIN ZHOU, QIUSHUANG SHENG, NA LU
  • Patent number: 11387426
    Abstract: A flexible display panel and a flexible display device are provided. The flexible display panel includes a flexible screen layer and an elastic support layer; the flexible screen layer and the elastic support layer are stacked; the elastic support layer includes a support mechanism and an elastic mechanism, the support mechanism is configured to support the flexible screen layer and is rollable, and the elastic mechanism is configured to generate an anti-rolling elastic force to maintain flatness of the flexible screen layer if the flexible screen layer is unrolled.
    Type: Grant
    Filed: January 17, 2019
    Date of Patent: July 12, 2022
    Assignees: BEIJING BOE OPTOELECTRONICS TECHNOLOGY CO., LTD., BOE TECHNOLOGY GROUP CO., LTD.
    Inventors: Shaopeng Xu, Hao Wu, Xuzhong Liu, Na An, Zongwei Luo, Baolei Guo, Gang Ci, Xiao Ma, Xinfeng Gong, Bin Xu, Zhenhua Luo, Zheng Zhang, Qingzhu Guan, Wei Su, Jinzhao Zhou, Guochun Wang, Zuoxin Yu, Dianzhong Liu
  • Patent number: 11381909
    Abstract: Some embodiments of the present disclosure provide a method and an apparatus for forming a differential beam, a method and an apparatus for processing a signal, and a chip. The method for forming a differential beam includes: obtaining a differential beam forming signal according to an input signal acquired by two microphones in a microphone array (101); and performing a nonlinear adjustment on at least an amplitude of the differential beam forming signal based on a distance between the two microphones and a signal frequency of the input signal to obtain the adjusted differential beam forming signal (102). With the above solution, a constant beam characteristic of the differential beam forming signal can be ensured as much as possible for microphone arrays of different specifications.
    Type: Grant
    Filed: October 23, 2020
    Date of Patent: July 5, 2022
    Assignee: Shenzhen Goodix Technology Co., Ltd.
    Inventors: Na Li, Guoliang Li, Xinshan Wang, Hu Zhu, Hongjing Guo
  • Publication number: 20220108147
    Abstract: Described are techniques for predictive microservice activation. The techniques include training a machine learning model using a plurality of sequences of coordinates, where the plurality of sequences of coordinates are respectively based upon a corresponding plurality of series of vectors generated from historical usage data for an application and its associated microservices. The techniques further include inputting a new sequence of coordinates representing a series of application operations to the machine learning model. The techniques further include identifying a predicted microservice for future utilization based on an output vector generated by the machine learning model. The techniques further include activating the predicted microservice prior to the predicted microservice being called by the application.
    Type: Application
    Filed: October 1, 2020
    Publication date: April 7, 2022
    Inventors: Meng Wan, Li Na Guo, Wang Liu, Xue Rui Hu, Mei Qin Si, Hong Yan Zhang
  • Publication number: 20220045684
    Abstract: A charge pump (321), a phase-locked loop circuit (301), and a clock control apparatus are provided, related to the field of wireless communications technologies, to implement a high-speed and low-noise charge pump in the clock control apparatus. The charge pump includes a degeneration circuit (3210), a charging current source transistor (Mio 1), a switch circuit (3211) and a discharging current source transistor (Mc 2). The charging current source transistor is configured to provide a charging current. The degeneration circuit is coupled between a first terminal of the charging current source transistor and a power supply terminal. The degeneration circuit is configured to degrade a first voltage corresponding to the power supply terminal to a second voltage. The switch circuit is coupled between a second terminal of the charging current source transistor and a load. The switch circuit is configured to control a charging current output to the load.
    Type: Application
    Filed: October 25, 2021
    Publication date: February 10, 2022
    Inventors: Na GUO, Qing MIN
  • Patent number: 11219161
    Abstract: A hand-propelled power tool includes a main body, a handle assembly, a fixing plate assembly, and a walking assembly connected to the main body. The handle assembly includes a first connecting rod and a second connecting rod. The first connecting rod is provided with a first adjusting assembly. The second connecting rod is provided with a second adjusting assembly. The first adjusting assembly and the second adjusting assembly form a linkage by a connecting member. The first adjusting assembly and the second adjusting assembly include a first movement state and a second movement state. When in the first movement state, the connecting member can transmit a force between the first adjusting assembly and the second adjusting assembly. When in the second movement state, the connecting member does not transmit a force between the first adjusting assembly and the second adjusting assembly.
    Type: Grant
    Filed: July 7, 2020
    Date of Patent: January 11, 2022
    Assignee: Nanjing Chervon Industry Co., Ltd.
    Inventors: Guangqian Zhu, Na Guo, Toshinari Yamaoka, Fangjie Nie, Qi Zhang
  • Publication number: 20210340509
    Abstract: The present disclosure relates to a reverse transcriptase and an application thereof. The reverse transcriptase has mutation sites such as R450H compared with the wild-type M-MLV reverse transcriptase. The reverse transcriptase has increased polymerase activity, improved thermal stability, and reduced RNase H activity.
    Type: Application
    Filed: June 25, 2021
    Publication date: November 4, 2021
    Inventors: Huanhuan Liu, Na Guo, Huizhen Li, Zhougang Zhang, Hongyan Han, Miaomiao Guo, Yue Zheng, Yuliang Dong, Wenwei Zhang, Chongjun Xu
  • Publication number: 20210093729
    Abstract: Disclosed herein is a preparation method and use of a surface double-modified human serum albumin as a tumor targeting nano drug carrier, wherein the targeting nano drug carrier includes human serum albumin (HSA), polyethylene glycol and E-selectin peptide ligand. The targeting nano drug carrier is formed by coupling the E-selectin peptide ligand and polyethylene glycol to the surface of HSA by thioether linker formed between the sulfhydryl group of E-selectin peptide ligand and activated HSA. The targeting nano drug carrier can encapsulate hydrophobic antitumor drugs and form nanoparticles with certain particle size after treatment, which can not only increase the solubility and stability of the hydrophobic antitumor drugs, but also can actively recognize and bind E-selectin which is highly expressed on activated endothelial cells at tumor site, competitively inhibit the interaction between E-selectin and tumor cells, and thus inhibit the adhesion and migration of tumor cells.
    Type: Application
    Filed: September 25, 2020
    Publication date: April 1, 2021
    Inventors: Na GUO, Peng YU, Fengyan LI, Jingjing TANG, Tiantian HAO, Ying FU, Haomeng WANG, Yuou TENG, Dong ` WANG
  • Publication number: 20210016817
    Abstract: A hand-propelled power tool includes a main body, a handle assembly, a fixing plate assembly, and a walking assembly connected to the main body. The handle assembly includes a first connecting rod and a second connecting rod. The first connecting rod is provided with a first adjusting assembly. The second connecting rod is provided with a second adjusting assembly. The first adjusting assembly and the second adjusting assembly form a linkage by a connecting member. The first adjusting assembly and the second adjusting assembly include a first movement state and a second movement state. When in the first movement state, the connecting member can transmit a force between the first adjusting assembly and the second adjusting assembly. When in the second movement state, the connecting member does not transmit a force between the first adjusting assembly and the second adjusting assembly.
    Type: Application
    Filed: July 7, 2020
    Publication date: January 21, 2021
    Inventors: Guangqian Zhu, Na Guo, Toshinari Yamaoka, Fangjie Nie, Qi Zhang
  • Publication number: 20190358219
    Abstract: Disclosed is a targeted delivery system for a hydrophobic antitumor drug, referring to conjugates of E-selectin polypeptide ligand-polyethylene glycol-antitumor drug connected by different link bridges containing disulfide bonds. The synthesis of the conjugates, antitumor activity evaluation, the particle size and morphology characteristics of nanoparticles self-assembled by the conjugates in an aqueous solution, and the release of the antitumor drug in different conditions are comprised. The conjugates can actively target at vessels of a tumor site by the E-selectin peptide ligand, and can also self-assemble into nanoparticles in an aqueous solution, so as to be passively targeted at the tumor site by EPR effect.
    Type: Application
    Filed: July 21, 2016
    Publication date: November 28, 2019
    Applicant: Tianjin University of Science & Technology
    Inventors: Peng YU, Na GUO, Dong WANG, Yuou TENG, Tiantian HAO, Huan LIU, Tianle ZHANG, Xiuzhuan SHANG
  • Patent number: 9718787
    Abstract: Disclosed are a phthalic hydrazide (phthalazine ketone) compound, and a pharmaceutical composition comprising the same. As a DNA repair enzyme poly (ADP-ribozyme) polymerase inhibitor, the compound and the pharmaceutical composition can effectively treat diseases involving PARP enzymatic activity, including cancer, neural degenerative diseases, inflammation and the like.
    Type: Grant
    Filed: August 13, 2015
    Date of Patent: August 1, 2017
    Assignee: CHENGDU DI'AO PHARMACEUTICAL GROUP CO., LTD.
    Inventors: Jianxin Ji, Na Guo, Ting Xue, Bingqiang Kang, Xinfa Ye, Xin Chen, Tao Zhang
  • Publication number: 20150368205
    Abstract: Disclosed are a phthalic hydrazide (phthalazine ketone) compound, and a pharmaceutical composition comprising the same. As a DNA repair enzyme poly (ADP-ribozyme) polymerase inhibitor, the compound and the pharmaceutical composition can effectively treat diseases involving PARP enzymatic activity, including cancer, neural degenerative diseases, inflammation and the like.
    Type: Application
    Filed: August 13, 2015
    Publication date: December 24, 2015
    Inventors: Jianxin JI, Na GUO, Ting XUE, Bingqiang KANG, Xinfa YE, Xin CHEN, Tao ZHANG
  • Patent number: 9187430
    Abstract: Disclosed are a phthalic hydrazide (phthalazine ketone) compound, and a pharmaceutical composition comprising the same. As a DNA repair enzyme poly (ADP-ribozyme) polymerase inhibitor, the compound and the pharmaceutical composition can effectively treat diseases involving PARP enzymatic activity, including cancer, neural degenerative diseases, inflammation and the like.
    Type: Grant
    Filed: December 3, 2012
    Date of Patent: November 17, 2015
    Assignee: CHENGDU DI'AO PHARMACEUTICAL GROUP CO., LTD.
    Inventors: Jianxin Ji, Na Guo, Ting Xue, Bingqiang Kang, Xinfa Ye, Xin Chen, Tao Zhang
  • Publication number: 20150051211
    Abstract: Disclosed are a phthalic hydrazide (phthalazine ketone) compound, and a pharmaceutical composition comprising the same. As a DNA repair enzyme poly (ADP-ribozyme) polymerase inhibitor, the compound and the pharmaceutical composition can effectively treat diseases involving PARP enzymatic activity, including cancer, neural degenerative diseases, inflammation and the like.
    Type: Application
    Filed: December 3, 2012
    Publication date: February 19, 2015
    Applicant: CHENGDU DI'AO PHARMACEUTICAL GROUP CO., LTD.
    Inventors: Jianxin Ji, Na Guo, Ting Xue, Bingqiang Kang, Xinfa Ye, Xin Chen, Tao Zhang
  • Patent number: 8940890
    Abstract: Disclosed is a synthesis method of a compound of formula 1,5-[[2(R)-[1(R)-[3,5-bis(trifluoromethyl)phenyl]ethoxyl]-3(S)-4-fluorophenyl-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazole-3-one (i.e. aprepitant), which comprises cyclizing a compound of formula 4 in a solvent, wherein R is C1-C5 alkyl. The intermediate for preparing aprepitant is also disclosed. The present method is especially suitable for industrial production of aprepitant.
    Type: Grant
    Filed: May 20, 2011
    Date of Patent: January 27, 2015
    Assignee: Chengdu DI'AO Pharmaceutical Group Co., Ltd.
    Inventors: Jianxin Ji, Qiang Zhang, Fengtian Du, Yi Jin, Tao Zhang, Na Guo, Xiaowei Yan, Yongrongn Yang, Bogang Li
  • Publication number: 20130109853
    Abstract: Disclosed is a synthesis method of a compound of formula 1,5-[[2(R)-[1(R)-[3,5-bis(trifluoromethyl)phenyl]ethoxyl]-3(S)-4-fluorophenyl-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazole-3-one (i.e. aprepitant), which comprises cyclizing a compound of formula 4 in a solvent, wherein R is C1-C5 alkyl. The intermediate for preparing aprepitant is also disclosed. The present method is especially suitable for industrial production of aprepitant.
    Type: Application
    Filed: May 20, 2011
    Publication date: May 2, 2013
    Inventors: Jianxin Ji, Qiang Zhang, Fengtian Du, Yi Jin, Tao Zhang, Na Guo, Xiaowei Yan, Yongrong Yang, Bogang Li