Patents by Inventor Na Ji
Na Ji has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230016533Abstract: The present disclosure belongs to the technical field of starch processing, and in particular relates to slowly digestible starch (SDS) and a preparation method and use thereof. The SDS includes a starch granule and a non-starch polysaccharide coating coated on a surface of the starch granule. In the present disclosure, the non-starch polysaccharide coating coated on the surface of the starch granule can prevent an amylase from contacting the starch granule, increasing contents of the SDS and resistant starch (RS) in the SDS. Therefore, the SDS can delay a digestion process, increase a digestion time of the starch, and reduce the increase of blood glucose and insulin levels after the starch is digested and absorbed.Type: ApplicationFiled: July 5, 2022Publication date: January 19, 2023Applicant: Qingdao Agricultural UniversityInventors: Qingjie Sun, Congli Cui, Na Ji, Qianzhu Lin, Kaili Qin, Han Jiang, Liu Xiong
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Patent number: 11237371Abstract: A scanning microscope includes a light source for generating a light beam having a wavelength, ?, and beam-forming optics configured for receiving the light beam and generating a quasi-Bessel excitation beam that is directed into a sample. The quasi-Bessel beam has a lateral FWHM and an axial FWHM that is greater than ten times the lateral FWHM, and the beam-forming optics include an excitation objective having an axis oriented in a first direction. The microscope includes beam scanning optics configured for scanning the quasi-Bessel beam in one or more directions that are substantially perpendicular to the first direction, and a detector configured for detecting signal light received from positions within the sample that are illuminated by the quasi-Bessel beam. The signal light is generated in response to an interaction of the excitation beam with the sample, and the signal light is imaged, at least in part, by the excitation objective, onto the detector.Type: GrantFiled: October 19, 2020Date of Patent: February 1, 2022Assignee: Howard Hughes Medical InstituteInventors: Na Ji, Rongwen Lu
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Publication number: 20210048657Abstract: A scanning microscope includes a light source for generating a light beam having a wavelength, ?, and beam-forming optics configured for receiving the light beam and generating a quasi-Bessel excitation beam that is directed into a sample. The quasi-Bessel beam has a lateral FWHM and an axial FWHM that is greater than ten times the lateral FWHM, and the beam-forming optics include an excitation objective having an axis oriented in a first direction. The microscope includes beam scanning optics configured for scanning the quasi-Bessel beam in one or more directions that are substantially perpendicular to the first direction, and a detector configured for detecting signal light received from positions within the sample that are illuminated by the quasi-Bessel beam. The signal light is generated in response to an interaction of the excitation beam with the sample, and the signal light is imaged, at least in part, by the excitation objective, onto the detector.Type: ApplicationFiled: October 19, 2020Publication date: February 18, 2021Inventors: Na Ji, Rongwen Lu
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Patent number: 10809510Abstract: A scanning microscope includes a light source for generating a light beam having a wavelength, ?, and beam-forming optics configured for receiving the light beam and generating a quasi-Bessel excitation beam that is directed into a sample. The quasi-Bessel beam has a lateral FWHM and an axial FWHM that is greater than ten times the lateral FWHM, and the beam-forming optics include an excitation objective having an axis oriented in a first direction. The microscope includes beam scanning optics configured for scanning the quasi-Bessel beam in one or more directions that are substantially perpendicular to the first direction, and a detector configured for detecting signal light received from positions within the sample that are illuminated by the quasi-Bessel beam. The signal light is generated in response to an interaction of the excitation beam with the sample, and the signal light is imaged, at least in part, by the excitation objective, onto the detector.Type: GrantFiled: February 5, 2020Date of Patent: October 20, 2020Assignee: Howard Hughes Medical InstituteInventors: Na Ji, Rongwen Lu
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Publication number: 20200249453Abstract: A scanning microscope includes a light source for generating a light beam having a wavelength, ?, and beam-forming optics configured for receiving the light beam and generating a quasi-Bessel excitation beam that is directed into a sample. The quasi-Bessel beam has a lateral FWHM and an axial FWHM that is greater than ten times the lateral FWHM, and the beam-forming optics include an excitation objective having an axis oriented in a first direction. The microscope includes beam scanning optics configured for scanning the quasi-Bessel beam in one or more directions that are substantially perpendicular to the first direction, and a detector configured for detecting signal light received from positions within the sample that are illuminated by the quasi-Bessel beam. The signal light is generated in response to an interaction of the excitation beam with the sample, and the signal light is imaged, at least in part, by the excitation objective, onto the detector.Type: ApplicationFiled: February 5, 2020Publication date: August 6, 2020Inventors: Na Ji, Rongwen Lu
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Patent number: 10578849Abstract: A scanning microscope includes a light source for generating a light beam having a wavelength, ?, and beam-forming optics configured for receiving the light beam and generating a quasi-Bessel excitation beam that is directed into a sample. The quasi-Bessel beam has a lateral FWHM and an axial FWHM that is greater than ten times the lateral FWHM, and the beam-forming optics include an excitation objective having an axis oriented in a first direction. The microscope includes beam scanning optics configured for scanning the quasi-Bessel beam in one or more directions that are substantially perpendicular to the first direction, and a detector configured for detecting signal light received from positions within the sample that are illuminated by the quasi-Bessel beam. The signal light is generated in response to an interaction of the excitation beam with the sample, and the signal light is imaged, at least in part, by the excitation objective, onto the detector.Type: GrantFiled: February 9, 2018Date of Patent: March 3, 2020Assignee: Howard Hughes Medical InstituteInventors: Na Ji, Rongwen Lu
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Publication number: 20180224644Abstract: A scanning microscope includes a light source for generating a light beam having a wavelength, ?, and beam-forming optics configured for receiving the light beam and generating a quasi-Bessel excitation beam that is directed into a sample. The quasi-Bessel beam has a lateral FWHM and an axial FWHM that is greater than ten times the lateral FWHM, and the beam-forming optics include an excitation objective having an axis oriented in a first direction. The microscope includes beam scanning optics configured for scanning the quasi-Bessel beam in one or more directions that are substantially perpendicular to the first direction, and a detector configured for detecting signal light received from positions within the sample that are illuminated by the quasi-Bessel beam. The signal light is generated in response to an interaction of the excitation beam with the sample, and the signal light is imaged, at least in part, by the excitation objective, onto the detector.Type: ApplicationFiled: February 9, 2018Publication date: August 9, 2018Inventors: Na Ji, Rongwen Lu
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Patent number: 8730573Abstract: Microscopy techniques in which a rear pupil of an optical system is segmented and the segments are individually controlled with a wavefront modulating device to control the direction and phase of individual beamlets of an excitation or emission beam in the optical system, thereby providing an adaptive optics correction to sample and system induced aberrations.Type: GrantFiled: July 9, 2010Date of Patent: May 20, 2014Assignee: Howard Hughes Medical InstituteInventors: Eric Betzig, Na Ji
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Patent number: 8718106Abstract: An apparatus includes a pulsed laser source that produces a pulsed laser beam at an input repetition rate and an input pulse power; a passive pulse splitter that receives the pulsed laser beam and outputs a signal including a plurality of sub-pulses for each input pulse of the pulsed laser beam, where the sub-pulses have a repetition rate that is greater than the input repetition rate and at least two of the sub-pulses have power less than the input pulse power; a sample accommodating structure configured to accommodate a sample placed in the path of a sample beam that is formed from the beam that exits the pulse splitter; and a detector that receives a signal of interest emitted from a sample accommodated by the sample accommodating structure based on the incident sample beam.Type: GrantFiled: May 3, 2011Date of Patent: May 6, 2014Assignee: Howard Hughes Medical InstituteInventors: Na Ji, Eric Betzig
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Patent number: 8692032Abstract: Tungsten carbide catalysts are used in preparation of ethylene glycol by hydrogenating degradation of cellulose. The catalyst includes tungsten carbide as main catalytic active component, added with small amount of one or more transition metals such as nickel, cobalt, iron, ruthenium, rhodium, palladium, osmium, iridium, platinum, and copper as the second metal, supported on one or more porous complex supports such as active carbon, alumina, silica, titanium dioxide, silicon carbide, zirconium oxide, for conversion of cellulose to ethylene glycol. The catalyst realizes high efficiency, high selectivity, and high yield in the conversion of cellulose to ethylene glycol at the temperature of 120-300° C., hydrogen pressure of 1-10 MPa, and hydrothermal conditions. Compared to the existing industrial synthetic method of ethylene glycol using ethylene as feedstock, the invention has the advantages of using renewable raw material resources, environment friendly process, and excellent atom economy.Type: GrantFiled: June 29, 2012Date of Patent: April 8, 2014Assignee: Dalian Institute of Chemical Physics, Chinese Academy of SciencesInventors: Tao Zhang, Na Ji, Mingyuan Zheng, Aiqin Wang, Yuying Shu, Xiaodong Wang, Jingguang Chen
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Patent number: 8629413Abstract: A method of manipulating a focused light beam includes focusing a beam of excitation light with a lens to a focal spot within a sample, where a cross-section of the beam includes individual beamlets. Directions and/or relative phases of the individual beamlets of the excitation beam at a rear pupil of the lens are individually varied with a wavefront modulating element, and emission light emitted from the focal spot is detected while the directions or relative phases of individual beamlets are varied. The directions of individual beamlets are controlled to either maximize or minimize the emission light from the focal spot, and the relative phases of individual beamlets are controlled to increase the emission light from the focal spot.Type: GrantFiled: July 16, 2012Date of Patent: January 14, 2014Assignee: Howard Hughes Medical InstituteInventors: Eric Betzig, Na Ji
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Publication number: 20130181143Abstract: A method of manipulating a focused light beam includes focusing a beam of excitation light with a lens to a focal spot within a sample, where a cross-section of the beam includes individual beamlets. Directions and/or relative phases of the individual beamlets of the excitation beam at a rear pupil of the lens are individually varied with a wavefront modulating element, and emission light emitted from the focal spot is detected while the directions or relative phases of individual beamlets are varied. The directions of individual beamlets are controlled to either maximize or minimize the emission light from the focal spot, and the relative phases of individual beamlets are controlled to increase the emission light from the focal spot.Type: ApplicationFiled: July 16, 2012Publication date: July 18, 2013Applicant: HOWARD HUGHES MEDICAL INSTITUTEInventors: Eric Betzig, Na Ji
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Patent number: 8324433Abstract: A method for producing ethylene glycol, including (a) adding a polyhydroxy compound and water to a sealed high-pressure reactor, (b) removing air and introducing hydrogen, and (c) allowing the polyhydroxy compound to react in the presence of a catalyst while stiffing. The catalyst includes a first active ingredient and a second active ingredient. The first active ingredient includes a transition metal of Group 8, 9, or 10 selected from iron, cobalt, nickel, ruthenium, rhodium, palladium, iridium, and platinum, and/or a mixture thereof. The second active ingredient includes a metallic state of molybdenum and/or tungsten, or a carbide, nitride, or phosphide thereof. The method is carried out at a hydrogen pressure of 1-12 MPa, at a temperature of 120-300° C. for not less than 5 min in a one-step catalytic reaction. The efficiency, selectivity, and the yield of ethylene glycol are high. The preparation process is simple and the materials used are renewable.Type: GrantFiled: October 31, 2010Date of Patent: December 4, 2012Assignee: Dalian Institute of Chemical Physics, Chinese Academy of SciencesInventors: Tao Zhang, Mingyuan Zheng, Aiqin Wang, Na Ji, Jifeng Pang, Zhijun Tai, Likun Zhou, Jingguang Chen, Xiaodong Wang
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Publication number: 20120283487Abstract: Tungsten carbide catalysts are used in preparation of ethylene glycol by hydrogenating degradation of cellulose. The catalyst includes tungsten carbide as main catalytic active component, added with small amount of one or more transition metals such as nickel, cobalt, iron, ruthenium, rhodium, palladium, osmium, iridium, platinum, and copper as the second metal, supported on one or more porous complex supports such as active carbon, alumina, silica, titanium dioxide, silicon carbide, zirconium oxide, for conversion of cellulose to ethylene glycol. The catalyst realizes high efficiency, high selectivity, and high yield in the conversion of cellulose to ethylene glycol at the temperature of 120-300° C., hydrogen pressure of 1-10 MPa, and hydrothermal conditions. Compared to the existing industrial synthetic method of ethylene glycol using ethylene as feedstock, the invention has the advantages of using renewable raw material resources, environment friendly process, and excellent atom economy.Type: ApplicationFiled: June 29, 2012Publication date: November 8, 2012Applicant: Dalian Institute of Chemical Physics, Chinese Academy of SciencesInventors: Tao Zhang, Na JI, Mingyuan Zheng, Aiqin WANG, Yuying SHU, Xiaodong WANG, Jingguang CHEN
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Publication number: 20110206075Abstract: An apparatus includes a pulsed laser source that produces a pulsed laser beam at an input repetition rate and an input pulse power; a passive pulse splitter that receives the pulsed laser beam and outputs a signal including a plurality of sub-pulses for each input pulse of the pulsed laser beam, where the sub-pulses have a repetition rate that is greater than the input repetition rate and at least two of the sub-pulses have power less than the input pulse power; a sample accommodating structure configured to accommodate a sample placed in the path of a sample beam that is formed from the beam that exits the pulse splitter; and a detector that receives a signal of interest emitted from a sample accommodated by the sample accommodating structure based on the incident sample beam.Type: ApplicationFiled: May 3, 2011Publication date: August 25, 2011Applicant: HOWARD HUGHES MEDICAL INSTITUTEInventors: Na Ji, Eric Betzig
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Patent number: 7961764Abstract: An apparatus includes a pulsed laser source that produces a pulsed laser beam at an input repetition rate and an input pulse power, a passive pulse splitter that receives the pulsed laser beam and outputs a signal including a plurality of sub-pulses for each input pulse of the pulsed laser beam, a sample, and a detector. The output signal has a repetition rate that is greater than the input repetition rate and the powers of each of the sub-pulses are less than the input pulse power. The sample is placed in the path of a sample beam that is formed from the beam that exits the pulse splitter. The detector receives a signal of interest emitted from the sample.Type: GrantFiled: July 18, 2008Date of Patent: June 14, 2011Assignee: Howard Hughes Medical InstituteInventors: Na Ji, Eric Betzig
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Patent number: 7960594Abstract: A method for preparing ethylene glycol from cellulose uses the cellulose as the feed for the reaction. The cellulose conversion is performed over catalysts which are composed of the metallic state, carbides, nitrides, or phosiphides of molybdenum or tungsten, and metallic cobalt, nickel, ruthenium, rhodium, palladium, iridium, and platinum of the group 8, 9, or 10 transition metals. The catalytic conversion of cellulose is conducted at 120 to 300° C. and hydrogen pressure 1 to 12 MPa under the hydrothermal conditions to achieve the high efficiency, high selectivity, and high yield of ethylene glycol. Compared to the existing method of preparing ethylene glycol from ethylene, the method, using the renewable raw material for the reaction, is friendly to the environment, and has high atom economy.Type: GrantFiled: October 31, 2008Date of Patent: June 14, 2011Inventors: Tao Zhang, Mingyuan Zheng, Na Ji, Aigin Wang, Yuying Shu, Hui Wang, Xiaodong Wang, Jingguang Chen
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Publication number: 20110046419Abstract: A method for producing ethylene glycol, including (a) adding a polyhydroxy compound and water to a sealed high-pressure reactor, (b) removing air and introducing hydrogen, and (c) allowing the polyhydroxy compound to react in the presence of a catalyst while stiffing. The catalyst includes a first active ingredient and a second active ingredient. The first active ingredient includes a transition metal of Group 8, 9, or 10 selected from iron, cobalt, nickel, ruthenium, rhodium, palladium, iridium, and platinum, and/or a mixture thereof. The second active ingredient includes a metallic state of molybdenum and/or tungsten, or a carbide, nitride, or phosphide thereof. The method is carried out at a hydrogen pressure of 1-12 MPa, at a temperature of 120-300° C. for not less than 5 min in a one-step catalytic reaction. The efficiency, selectivity, and the yield of ethylene glycol are high. The preparation process is simple and the materials used are renewable.Type: ApplicationFiled: October 31, 2010Publication date: February 24, 2011Applicant: Dalian Institute of Chemical Physics, Chinese Academy of SciencesInventors: Tao ZHANG, Mingyuan ZHENG, Aiqin WANG, Na JI, Jifeng PANG, Zhijun TAI, Likun ZHOU, Jingguang CHEN, Xiaodong WANG
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Publication number: 20110006231Abstract: Microscopy techniques in which a rear pupil of an optical system is segmented and the segments are individually controlled with a wavefront modulating device to control the direction and phase of individual beamlets of an excitation or emission beam in the optical system, thereby providing an adaptive optics correction to sample and system induced aberrations.Type: ApplicationFiled: July 9, 2010Publication date: January 13, 2011Applicant: HOWARD HUGHES MEDICAL INSTITUTEInventors: Eric Betzig, Na Ji
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Publication number: 20100256424Abstract: A method for preparing ethylene glycol from cellulose uses the cellulose as the feed for the reaction. The cellulose conversion is performed over catalysts which are composed of the metallic state, carbides, nitrides, or phosiphides of molybdenum or tungsten, and metallic cobalt, nickel, ruthenium, rhodium, palladium, iridium, and platinum of the group 8, 9, or 10 transition metals. The catalytic conversion of cellulose is conducted at 120 to 300° C. and hydrogen pressure 1 to 12 MPa under the hydrothermal conditions to achieve the high efficiency, high selectivity, and high yield of ethylene glycol. Compared to the existing method of preparing ethylene glycol from ethylene, the method, using the renewable raw material for the reaction, is friendly to the environment, and has high atom economy.Type: ApplicationFiled: October 31, 2008Publication date: October 7, 2010Inventors: Tao Zhang, Mingyuan Zheng, Na Ji, Aigin Wang, Yuying Shu, Hui Wang, Xiaodong Wang, Jingguang Chen