Patents by Inventor Na-Kyung HAN

Na-Kyung HAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CHIMERIC ANTIGEN RECEPTOR COMPRISING ANTI-MESOTHELIN SCFV, AND USE THEREOF
    Publication number: 20240033291
    Abstract: Provided is an anti-mesothelin chimeric antigen receptor that specifically binds to mesothelin. The anti-mesothelin chimeric antigen receptor according to an aspect exhibits a specific binding ability for mesothelin, and thus, may be useful for preventing or treating cancer in which mesothelin is overexpressed.
    Type: Application
    Filed: May 25, 2022
    Publication date: February 1, 2024
    Inventors: Jae Hyung AN, Na Kyung HAN
  • Chimeric antigen receptor comprising anti-mesothelin scFv, and use thereof
    Patent number: 11883433
    Abstract: Provided is an anti-mesothelin chimeric antigen receptor that specifically binds to mesothelin. The anti-mesothelin chimeric antigen receptor according to an aspect exhibits a specific binding ability for mesothelin, and thus, may be useful for preventing or treating cancer in which mesothelin is overexpressed.
    Type: Grant
    Filed: May 25, 2022
    Date of Patent: January 30, 2024
    Assignee: CELLENGENE INC.
    Inventors: Jae Hyung An, Na Kyung Han
  • Anti-mesothelin chimeric antigen receptor specifically binding to mesothelin
    Patent number: 11795215
    Abstract: Provided is an anti-mesothelin chimeric antigen receptor specifically binding to mesothelin. The anti-mesothelin chimeric antigen receptor according to an aspect exhibits an ability to specifically bind to mesothelin, and thus may be usefully applied to preventing or treating mesothelin-overexpressing cancers.
    Type: Grant
    Filed: April 30, 2021
    Date of Patent: October 24, 2023
    Assignee: CELLENGENE INC
    Inventors: Jae Hyung An, Na Kyung Han
  • ANTI-MESOTHELIN CHIMERIC ANTIGEN RECEPTOR SPECIFICALLY BINDING TO MESOTHELIN
    Publication number: 20230151082
    Abstract: Provided is an anti-mesothelin chimeric antigen receptor specifically binding to mesothelin. The anti-mesothelin chimeric antigen receptor according to an aspect exhibits an ability to specifically bind to mesothelin, and thus may be usefully applied to preventing or treating mesothelin-overexpressing cancers.
    Type: Application
    Filed: April 30, 2021
    Publication date: May 18, 2023
    Inventors: Jae Hyung AN, Na Kyung HAN
  • Composition comprising inhibitor against PAPSS2 gene or protein encoded by gene for inducing senescence in tumor cells and method for inducing senescence in tumor cells using the same
    Patent number: 9550995
    Abstract: Provided is a composition for inducing tumor cell senescence and a method for inducing tumor cell senescence using the same. The composition can inhibit a PAPSS2 gene in a tumor cell to thereby induce senescence of the tumor cell, and if the composition is used concurrently with irradiation of the tumor cell, the composition can improve the sensitivity of the tumor cell to radiation.
    Type: Grant
    Filed: May 20, 2013
    Date of Patent: January 24, 2017
    Assignees: Korea Institute of Radiological & Medical Sciences, Inha University Research and Business Foundation
    Inventors: Jae-Seon Lee, Seung Hee Jung, Bong Cho Kim, Hyung Chul Lee, Na-Kyung Han, Mi-Na Hong
  • COMPOSITION COMPRISING INHIBITOR AGAINST PAPSS2 GENE OR PROTEIN ENCODED BY GENE FOR INDUCING SENESCENCE IN TUMOR CELLS AND METHOD FOR INDUCING SENESCENCE IN TUMOR CELLS USING THE SAME
    Publication number: 20160060633
    Abstract: Provided is a composition for inducing tumor cell senescence and a method for inducing tumor cell senescence using the same. The composition can inhibit a PAPSS2 gene in a tumor cell to thereby induce senescence of the tumor cell, and if the composition is used concurrently with irradiation of the tumor cell, the composition can improve the sensitivity of the tumor cell to radiation.
    Type: Application
    Filed: May 20, 2013
    Publication date: March 3, 2016
    Inventors: Jae-Sun LEE, Seung Hee JUNG, Bong Cho KIM, Hyung Chul LEE, Na-Kyung HAN, Mi-Na HONG
  • METHOD FOR DETECTING PREMATURE SENESCENCE IN TUMOR CELLS AND A KIT FOR DETECTING PREMATURE SENESCENCE IN TUMOR CELLS
    Publication number: 20100304409
    Abstract: The present invention provides a method for detecting senescence in tumor cells and a kit for detecting senescence in tumor cells. eEF1A1 and CD markers are provided, wherein changes in the levels of the markers are correlated with premature senescence of tumor cells.
    Type: Application
    Filed: May 26, 2009
    Publication date: December 2, 2010
    Applicant: KOREA INSTITUTE OF RADIOLOGICAL & MEDICAL SCIENCES
    Inventors: Jae-Seon LEE, Kee-Ho LEE, Hae-Ok BYUN, Na-Kyung HAN