Patents by Inventor Na Lee

Na Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel endonuclease of immune cell, process for producing the same and immune adjuvant using the same
    Publication number: 20070173468
    Abstract: The present invention relates to a novel endonuclease enzyme which is secreted from immune cell and recognizes bacterial DNA as foreign agent and processes it to produce about 10 bp single-stranded oligonucleotide including CpG motif which is involved in immune response. Also, the present invention relates to a process for producing the endonuclease which comprises culturing human B-lymphoblastic IM9 cell line or TPA-treated myelogenous U937 cell line on an appropriate medium to produce the said endonuclease and isolating the said endonuclease from the cell lysate or the culture medium. In addition, the present invention relates to an immune adjuvant comprising about 10 bp single-stranded oligonucleotide having CpG motif produced by treatment of bacterial DNA by the endonuclease.
    Type: Application
    Filed: June 4, 2004
    Publication date: July 26, 2007
    Applicant: Cheil Jedang Corporation
    Inventors: Yeong Jeon, Wan Park, Na Lee, Sang Jung, Doo Kim, Hyung Kwon
  • Novel endonuclease of immune cell, process for producing the same and immune adjuvant using the same
    Publication number: 20050203039
    Abstract: The present invention relates to a novel endonuclease enzyme which is secreted from immune cell and recognizes bacterial DNA as foreign agent and processes it to produce about 10 bp single-stranded oligonucleotide including CpG motif which is involved in immune response. Also, the present invention relates to a process for producing the endonuclease which comprises culturing human B-lymphoblastic IM9 cell line or TPA-treated myelogenous U937 cell line on an appropriate medium to produce the said endonuclease and isolating the said endonuclease from the cell lysate or the culture medium. In addition, the present invention relates to an immune adjuvant comprising about 10 bp single-stranded oligonucleotide having CpG motif produced by treatment of bacterial DNA by the endonuclease.
    Type: Application
    Filed: June 4, 2004
    Publication date: September 15, 2005
    Applicant: Cheil Jedang Corporation
    Inventors: Yeong Jeon, Wan Park, Na Lee, Sang Jung, Doo Kim, Hyung Kwon