Patents by Inventor Na Ra JEON

Na Ra JEON has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Composition for the prevention and treatment of postmenopausal syndrome containing extracts or fractions of as an effective ingredient
    Patent number: 8524287
    Abstract: The present invention relates to a method for the prevention and treatment of postmenopausal syndrome containing the step of administering a pharmaceutically effective dose of the Aceriphyllum rossii or its fractions to a subject. The present inventors confirmed that the Aceriphyllum rossii extract or its fractions of the invention prepared by using water, alcohol or a mixed solvent thereof could promote the expression of the promoter containing estrogen responsive element (ERE) and accelerated the growth of MCF-7, the human breast tissue originated cell line, suggesting that they had estrogen activity. The inventors further confirmed that the extract or its fractions of the invention had the effect of promoting osteocyte differentiation, so that they could be effectively used for the prevention and treatment of postmenopausal syndrome such as hot flush, osteoporosis and phlebothrombosis caused by estrogen deficiency.
    Type: Grant
    Filed: July 2, 2010
    Date of Patent: September 3, 2013
    Assignee: Korea Institute of Science and Technology
    Inventors: Chu Won Nho, Na Ra Jeon, Kyung Su Kang, Saet Byoul Lee, Ji Hye Yoo, Suk Woo Kang, Byung Hun Um, Cheol-Ho Pan
  • COMPOSITION FOR THE PREVENTION AND TREATMENT OF POSTMENOPAUSAL SYNDROME CONTAINING EXTRACTS OR FRACTIONS OF ACERIPHYLLUM ROSSII AS AN EFFECTIVE INGREDIENT
    Publication number: 20110206784
    Abstract: The present invention relates to a method for the prevention and treatment of postmenopausal syndrome containing the step of administering a pharmaceutically effective dose of the Aceriphyllum rossii or its fractions to a subject. The present inventors confirmed that the Aceriphyllum rossii extract or its fractions of the invention prepared by using water, alcohol or a mixed solvent thereof could promote the expression of the promoter containing estrogen responsive element (ERE) and accelerated the growth of MCF-7, the human breast tissue originated cell line, suggesting that they had estrogen activity. The inventors further confirmed that the extract or its fractions of the invention had the effect of promoting osteocyte differentiation, so that they could be effectively used for the prevention and treatment of postmenopausal syndrome such as hot flush, osteoporosis and phlebothrombosis caused by estrogen deficiency.
    Type: Application
    Filed: July 2, 2010
    Publication date: August 25, 2011
    Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Chu Won NHO, Na Ra JEON, Kyung Su KANG, Saet Byoul LEE, Ji Hye YOO, Suk Woo KANG, Byung Hun UM, Cheol-Ho PAN