Abstract: Provided is a mesylate salt of methanesulfonic acid and a triazolopyrazine derivative of formula (1), pharmaceutical compositions thereof, methods of making the salt, and therapeutic use thereof:

Abstract: A camsylate salt of D(+)-10-camphorsulfonic acid and a triazolopyrazine derivative of formula (1), pharmaceutical compositions thereof, methods of making the salt, and therapeutic use thereof:

Abstract: A video coding method and an apparatus for refining predicted signals in intra prediction are disclosed. The video coding method and apparatus generate refined prediction signals approximating original video signals from predicted signals of intra prediction using a variable and fixed coefficient-based deep learning model to reduce the amount of data for residual signals, which are to be encoded.

Abstract: The present invention relates to a composition for exterminating fish parasites comprising an extract of Juglans mandshurica bark as an active ingredient, making it possible to safely and effectively exterminate scuticociliates using an extract derived from a natural material, instead of formalin that is highly harmful, which has been conventionally used to treat scuticociliatosis in fish.

Abstract: A display device including: pixels coupled to first scan lines, second scan lines, emission control lines, and data lines; a first scan driver configured to supply a first scan signal to each of the first scan lines at a first frequency; a second scan driver configured to supply a second scan signal to each of the second scan lines at a second frequency corresponding to a driving frequency of the pixels; an emission driver configured to supply an emission control signal to each of the emission control lines at the first frequency; a data driver configured to supply a data signal to each of the data lines at the second frequency; and a timing controller configured to control the first scan driver, the second scan driver, the emission driver, and the data driver.

Abstract: Systems and methods are provided for creating a sequence of turn-up processes for amplifiers. A method, according to one implementation, includes determining when a fiber span is initially installed in an optical line system or when an Optical Line Failure (OLF) in the fiber span has recovered. The optical line system includes a first set of amplifiers deployed at an upstream node and a second set of amplifiers deployed at a downstream node, the upstream node connected to the downstream node via the fiber span. In response to determining that the fiber span is initially installed in the optical line system or that an ORL in the fiber span has recovered, the method also includes sending a flag from the upstream node to the downstream node to allow the first set of amplifiers to perform a first turn-up process before the second set of amplifiers perform a second turn-up process.

Abstract: A method and an apparatus for a messaging service are disclosed. A method of operating a terminal on which an application for a messaging service is installed includes detecting a keyword from a text input through a message input window, cumulatively displaying the detected keyword on a suggest area, setting information about a link to a selected keyword in the text, and separately displaying the selected keyword from a non-selected keyword on the suggest area.

Abstract: A messaging service method and apparatus are disclosed. An operating method of a terminal on which an application for a messaging service is installed includes displaying a keyword of a first type in a chat interface, wherein the keyword of the first type is detected from a text input into a message input window of the chat interface in a first input mode, based on a request corresponding to a keyword of a second type detected from the text, changing an input mode of the chat interface to a second input mode, and in response to the input mode being changed, replacing displaying of the keyword of the first type with displaying of an interfacing object corresponding to the keyword of the second type.

Abstract: Disclosed are: a polymer electrolyte membrane which can prevent ionic conductor loss even upon the occurrence of chemical degradation in the ionic conductor according to long term use and thus can be significantly improved in chemical durability; a manufacturing method therefor; and an electrochemical device comprising same. The polymer electrolyte membrane of the present disclosure comprises a polymer electrolyte material. The polymer electrolyte material comprises an ionic conductor and a crosslinker unbound to the ionic conductor. The crosslinker has at least one cross-linkable functional group which can couple with the ionic conductor that has been degraded, thereby causing crosslinking with the ionic conductor.

Abstract: Disclosed is a reaction display method performed by a computer apparatus including processing circuitry, the reaction display method including displaying, by the processing circuitry, a content sharing screen with a voice over Internet protocol (VoIP) call screen during a VoIP call, the content sharing screen including shared media content, and a user of the computer apparatus participating in the VoIP call, receiving, by the processing circuitry, a position at which a reaction is input from the user during the VoIP call, sending reaction information and the position to at least one other user participating in the VoIP call, the reaction information corresponding to the reaction, and displaying an indication of the reaction on the VoIP call screen or the content sharing screen based on the position.

Abstract: A content sharing method performed by a computer apparatus including processing circuitry, the method including providing, by the processing circuitry, an interface in response to a user input during a voice over Internet protocol (VoIP) call, a user of the computer apparatus participating in the VoIP call, generating, by the processing circuitry, metadata of a VoIP call packet in response to a share request for content specified through the interface, the metadata including data corresponding to the share request, sending, by the processing circuitry, the metadata to another user participating in the VoIP call, and displaying, by the processing circuitry, a playback screen of the content with a call screen of the VoIP call, the content being shared during the VoIP call between the computer apparatus and another computer apparatus of the other user using the metadata.

Abstract: A pad assembly for power reception of an electric vehicle includes a receiving pad configured to support a receiving coil connected to an external component, and a magnetic complex layer disposed above or below the receiving coil. An increment in inductance per unit density of the magnetic complex layer disposed above or below the receiving coil is 25%·cm3/g or more compared to an increment in inductance per unit density of the magnetic complex layer alone not disposed above or below the receiving coil.

Abstract: A method, a system, and a non-transitory computer-readable record medium for providing a communication using a video call bot are disclosed. A video call method implemented by a computer apparatus, may include: in response to a request for inviting a chat bot to a video call in which a plurality of users comprising a user of the computer apparatus participate, displaying the chat bot on a display screen for the video call; transmitting, to a server, a command line that is associated with the chat bot and is extracted from an a voice input that is input to the computer apparatus during the video call; and in response to the command line, outputting a response to the command line through the chat bot that participates in the video call.

Abstract: The present disclosure relates to a coronavirus-specific double-stranded oligonucleotide and a use thereof. The present disclosure induces RNA interference specific to a coronavirus, particularly, to SARS-CoV, SARS-CoV-2, and a mutant thereof so as to effectively inhibit viral infection and proliferation, and is nearly unaffected by viral variants since a conserved sequence is mainly targeted. Therefore, the double-stranded oligonucleotide of the present disclosure may be effectively used in proliferation inhibition, infection prevention, and disease treatment of the coronavirus, and particularly, may be effectively used as an agent for preventing and treating COVID-19, which is the cause of the current pandemic.

Abstract: A pixel for a display device includes a light-emitting element, a first transistor including a first electrode electrically connected to a first node and controlling a driving current, a second transistor electrically connected between a data line and the first node and being turned on in response to a first scan signal supplied through a first scan line, a third transistor electrically connected between the second node and a third node electrically connected to a second electrode of the first transistor and being turned on in response to the first scan signal, and a fourth transistor being turned on in response to a second scan signal supplied through a second scan line, and applying a bias voltage to the first transistor. The fourth transistor is turned on at a first frequency. The second and third transistors are turned on at a second frequency different from the first frequency.

Abstract: The present invention relates to a humanized antibody specific to a Bacillus anthracis protective antigen and a preparation method thereof. An antibody library is created by obtaining a Bacillus anthracis protective antigen antibody of a monkey from immune cells obtained by immunizing a Bacillus anthracis protective antigen, an antibody specific to the Bacillus anthracis protective antigen is selected from the created antibody library, and, on the basis of the antibody, a humanized antibody specific to the Bacillus anthracis protective antigen is finally selected by creating a humanized antibody library against a Bacillus anthracis protective antigen.

Abstract: A video encoding method and a video decoding method is provided for generating improved picture quality for a current frame and improving encoding efficiency. The video encoding method and the video decoding method further include an in-loop filter that detects a reference region from a current frame and a reference frame using a deep learning-based detection model and then combines the detected reference region with the current frame.

Abstract: A display device includes pixels which are connected to first scan lines, second scan lines, third scan lines, emission control lines, and data lines; a scan driver which supplies a bias scan signal to each of the third scan lines at a first frequency and supplies a scan signal to each of the first scan line and the second scan line at a second frequency which corresponds to an image refresh rate of each of the pixels; an emission driver which supplies an emission control signal to each of the emission control lines at the first frequency; a data driver which supplies a data signal to each of the data lines at the second frequency; and a timing controller which controls driving of the scan driver, the emission driver, and the data driver.

Abstract: The present invention relates to a composition for treating or sensitizing interferon beta resistant cancer disease comprising cFLIP siRNA, and, more specifically, to a pharmaceutical composition for treating interferon beta resistant cancer disease, comprising, as an active ingredient: (a) an siRNA complementarily binding to mRNA of a cFLIP gene; and (b) a human interferon beta variant which comprises glycine-asparagine-isoleucine-threonine-valine sequence (GNITV) at C-terminus in a human natural interferon beta amino acid sequence shown in SEQ ID NO: 1, or has replaced the 27th arginine amino acid with threonine or serine.

Abstract: An organic light emitting display capable of substantially preventing IR drop of a power source wiring line and coupling of data lines is disclosed. In one aspect, the organic light emitting display includes pairs of data lines between adjacent sub-pixels. The data lines are arranged to run parallel with a coupling blocking wiring line provided between each pair.