Abstract: Disclosed in the present disclosure are a novel injection polyaminopolycarboxylic acid-modified abiraterone derivative for treatment of prostate tumor, a pharmaceutical preparation containing the polyaminopolycarboxylic acid-modified abiraterone derivative, a preparation method, and an application. The polyaminopolycarboxylic acid-modified abiraterone derivative has the following structure (I). The polyaminopolycarboxylic acid-modified abiraterone derivative in the present disclosure has good water solubility, can be completely dissolved in an aqueous solution of sodium bicarbonate, is simple and convenient to prepare, high in yield, and suitable for large-scale production, has a remarkable effect in resisting tumors, can be used for treating prostate cancer tumor, and has the characteristics of high efficiency and low toxicity.

Abstract: After obtaining a virtual machine migration message, a control node performs first network configuration on a virtual switch of a new virtual machine. After performing the first network configuration, the control node creates the new virtual machine, and performs second network configuration on a second virtual switch in a virtual network in which a to-be-migrated virtual machine is located. In the present application, before the new virtual machine is created, a network connection of the to-be-migrated virtual machine is maintained, and a part of network configuration for the new virtual machine is completed.

Abstract: Disclosed in the present disclosure are a novel injection polyaminopolycarboxylic acid-modified abiraterone derivative for treatment of prostate tumor, a pharmaceutical preparation containing the polyaminopolycarboxylic acid-modified abiraterone derivative, a preparation method, and an application. The polyaminopolycarboxylic acid-modified abiraterone derivative has the following structure (I). The polyaminopolycarboxylic acid-modified abiraterone derivative in the present disclosure has good water solubility, can be completely dissolved in an aqueous solution of sodium bicarbonate, is simple and convenient to prepare, high in yield, and suitable for large-scale production, has a remarkable effect in resisting tumors, can be used for treating prostate cancer tumor, and has the characteristics of high efficiency and low toxicity.

Abstract: A light emitter that operates through a display may cause display artifacts, even when the light emitter operates using non-visible wavelengths. Display artifacts caused by a light emitter that operates through a display may be referred to as emitter artifacts. To mitigate emitter artifacts, operating conditions for a display frame may be used to determine an optimal firing time for the light emitter during that display frame. The operating conditions used to determine the optimal firing time may include emitter operating conditions, display content statistics, display brightness, temperature, and refresh rate. Operating conditions from one or more previous frames may be stored in a frame buffer and may be used to help determine the optimal firing time for the light emitter during a display frame. Pixel values for the display may be modified to mitigate emitter artifacts.

Abstract: The present disclosure relates to the field of biology, in particular, to an anti-CLD18A2 VHH. The present disclosure provides an anti-CLD18A2 VHH. A complementarity determining region (CDR) of the anti-CLD18A2 VHH includes CDR1-CDR3 having amino acid sequences as shown below: CDR1 having an amino acid sequence represented by one of SEQ ID NO. 4-11, CDR2 having an amino acid sequence represented by one of SEQ ID NO. 19-26, and CDR3 having an amino acid sequence represented by one of SEQ ID NO.33-39. The anti-CLD18A2 VHH of the present disclosure can specifically bind to the epitope on CLD18A2, and the corresponding fusion protein thereof has good specificity and affinity for CLD18A2, and has a noticeable tumor suppression effect.

Abstract: The present disclosure relates to the field of biology, in particular, to an anti-CLD18A2 VHH. The present disclosure provides an anti-CLD18A2 VHH. A complementarity determining region (CDR) of the anti-CLD18A2 VHH includes CDR1-CDR3 having amino acid sequences as shown below: CDR1 having an amino acid sequence represented by one of SEQ ID NO. 4-11, CDR2 having an amino acid sequence represented by one of SEQ ID NO. 19-26, and CDR3 having an amino acid sequence represented by one of SEQ ID NO.33-39. The anti-CLD18A2 VHH of the present disclosure can specifically bind to the epitope on CLD18A2, and the corresponding fusion protein thereof has good specificity and affinity for CLD18A2, and has a noticeable tumor suppression effect.

Abstract: Aspects of the present invention provide an approach for improving communications between a software-defined networking (SDN) controller and a hardware gateway in a SDN. In an embodiment, a SDN proxy gateway is installed. The SDN proxy gateway communicates with the SDN controller on behalf of the hardware gateway. To accomplish this, the SDN proxy gateway processes a communication sent from the SDN controller to the hardware gateway. This communication includes a request from a computing node to establish a network communication channel. The SDN proxy gateway translates these instructions (e.g., the logical network and endpoint information), which are in the native format of the SDN controller, into a standardized hardware gateway protocol. The translated information that the hardware gateway can use to establish the network connection is then pushed to the hardware gateway by the proxy gateway.

Abstract: After obtaining a virtual machine migration message, a control node performs first network configuration on a virtual switch of a new virtual machine. After performing the first network configuration, the control node creates the new virtual machine, and performs second network configuration on a second virtual switch in a virtual network in which a to-be-migrated virtual machine is located. In the present application, before the new virtual machine is created, a network connection of the to-be-migrated virtual machine is maintained, and a part of network configuration for the new virtual machine is completed.

Abstract: Aspects of the present invention provide an approach for improving communications between a software-defined networking (SDN) controller and a hardware gateway in a SDN. In an embodiment, a SDN proxy gateway is installed. The SDN proxy gateway communicates with the SDN controller on behalf of the hardware gateway. To accomplish this, the SDN proxy gateway processes a communication sent from the SDN controller to the hardware gateway. This communication includes a request from a computing node to establish a network communication channel. The SDN proxy gateway translates these instructions (e.g., the logical network and endpoint information), which are in the native format of the SDN controller, into a standardized hardware gateway protocol. The translated information that the hardware gateway can use to establish the network connection is then pushed to the hardware gateway by the proxy gateway.

Abstract: Aspects of the present invention provide an approach for improving communications between a software-defined networking (SDN) controller and a hardware gateway in a SDN. In an embodiment, a SDN proxy gateway is installed. The SDN proxy gateway communicates with the SDN controller on behalf of the hardware gateway. To accomplish this, the SDN proxy gateway processes a communication sent from the SDN controller to the hardware gateway. This communication includes a request from a computing node to establish a network communication channel. The SDN proxy gateway translates these instructions (e.g., the logical network and endpoint information), which are in the native format of the SDN controller, into a standardized hardware gateway protocol. The translated information that the hardware gateway can use to establish the network connection is then pushed to the hardware gateway by the proxy gateway.

Abstract: Aspects provide optimized broadcast, unknown unicast, multicast packet (BUM) flooding. A flooding interface list is built for a network virtualization edge structure for an overlay network first virtual machine that includes one or more tunnel interfaces, one for each of a subset of the underlay network virtualization edge structures. In response to receiving a BUM packet from the first virtual machine at the first network virtualization edge structure, an overlay encapsulated packet is generated from the BUM packet and sent out to only those tunnel interfaces listed within the flooding interface list built for the virtual machine, thereby without sending to other network virtualization edge structures that do not have tunnel interfaces listed within the built flooding interface list.

Abstract: Aspects of the present invention provide an approach for improving communications between a software-defined networking (SDN) controller and a hardware gateway in a SDN. In an embodiment, a SDN proxy gateway is installed. The SDN proxy gateway communicates with the SDN controller on behalf of the hardware gateway. To accomplish this, the SDN proxy gateway processes a communication sent from the SDN controller to the hardware gateway. This communication includes a request from a computing node to establish a network communication channel. The SDN proxy gateway translates these instructions (e.g., the logical network and endpoint information), which are in the native format of the SDN controller, into a standardized hardware gateway protocol. The translated information that the hardware gateway can use to establish the network connection is then pushed to the hardware gateway by the proxy gateway.

Abstract: Apparatuses, methods, systems, and program products are disclosed for controller-based dynamic routing in a software defined network environment. A gateway module receives a routing protocol control packet at a virtual gateway of a software defined network (“SDN”). The SDN includes one or more virtual gateways that connect the SDN to one or more external networks. A routing control module forwards the received routing protocol control packet to a controller for the SDN. The SDN controller updates a routing information base for the SDN based on the received routing protocol control packet. An update module sends at least a portion of the routing information base to one or more external routers connected to the SDN.

Abstract: Aspects provide optimized broadcast, unknown unicast, multicast packet (BUM) flooding. A flooding interface list is built for a network virtualization edge structure for an overlay network first virtual machine that includes one or more tunnel interfaces, one for each of a subset of the underlay network virtualization edge structures. In response to receiving a BUM packet from the first virtual machine at the first network virtualization edge structure, an overlay encapsulated packet is generated from the BUM packet and sent out to only those tunnel interfaces listed within the flooding interface list built for the virtual machine, thereby without sending to other network virtualization edge structures that do not have tunnel interfaces listed within the built flooding interface list.

Abstract: Apparatuses, methods, systems, and program products are disclosed for controller-based dynamic routing in a software defined network environment. A gateway module receives a routing protocol control packet at a virtual gateway of a software defined network (“SDN”). The SDN includes one or more virtual gateways that connect the SDN to one or more external networks. A routing control module forwards the received routing protocol control packet to a controller for the SDN. The SDN controller updates a routing information base for the SDN based on the received routing protocol control packet. An update module sends at least a portion of the routing information base to one or more external routers connected to the SDN.

Abstract: A coating method for liquid crystal alignment film of TFT-LCD, at least two different sized nozzles are used to perform N nested hollow rectangular coatings, the N nested hollow rectangles are ordered based on 1, 2 to N measurements sequentially from the smallest to the biggest, and a smaller sized nozzle is employed for the Nth nested hollow rectangular coating on an edge.

Abstract: A coating method for liquid crystal alignment film of TFT-LCD including: forming a layer of hydrophobic film on a TFT/CF substrate corresponding to a non-display area, the hydrophobic film separates the TFT/CF substrate into a plurality of rectangular opened areas which are separated from each other, each of the rectangular opened areas corresponds to a display area and its outer frame is formed by the hydrophobic film; and coating of a liquid of a material of an alignment film along a boundary of the rectangular opened area. Accordingly, edge waves caused by spreading of drips of the material of the alignment film can be reduced, so that a precision of printing of the alignment film can be controlled effectively.

Abstract: A coating method for liquid crystal alignment film of TFT-LCD including: forming a layer of hydrophobic film on a TFT/CF substrate corresponding to a non-display area, the hydrophobic film separates the TFT/CF substrate into a plurality of rectangular opened areas which are separated from each other, each of the rectangular opened areas corresponds to a display area and its outer frame is formed by the hydrophobic film; and coating of a liquid of a material of an alignment film along a boundary of the rectangular opened area. Accordingly, edge waves caused by spreading of drips of the material of the alignment film can be reduced, so that a precision of printing of the alignment film can be controlled effectively.

Abstract: A coating method for liquid crystal alignment film of TFT-LCD, at least two different sized nozzles are used to perform N nested rectangular coatings, the N nested rectangles are ordered based on 1, 2 to N measurements sequentially from the smallest to the biggest, and a smaller sized nozzle is employed for the Nth nested rectangular coating on an edge.