Patents by Inventor Nabeel Nabulsi

Nabeel Nabulsi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Radiolabeled pharmaceuticals and methods of making and using same
    Patent number: 11518754
    Abstract: In one aspect, the invention comprises compounds that bind to the synaptic vesicle protein SV2A and that can be useful as radiotracers for positron emission tomography. In another aspect, the invention comprises methods of imaging the brain, measuring synaptic density or diagnosing neurological diseases such as Alzheimer's disease, psychiatric disorders such as depression, and metabolic disorders such as diabetes comprising detecting the compounds of the invention by positron emission tomography (PET).
    Type: Grant
    Filed: February 15, 2018
    Date of Patent: December 6, 2022
    Assignee: YALE UNIVERSITY
    Inventors: Yiyun Huang, Zhengxin Cai, Songye Li, Nabeel Nabulsi, Richard Carson
  • Radiolabeled Pharmaceuticals and Methods of Making and Using Same
    Publication number: 20200010447
    Abstract: In one aspect, the invention comprises compounds that bind to the synaptic vesicle protein SV2A and that can be useful as radiotracers for positron emission tomography. In another aspect, the invention comprises methods of imaging the brain, measuring synaptic density or diagnosing neurological diseases such as Alzheimer's disease, psychiatric disorders such as depression, and metabolic disorders such as diabetes comprising detecting the compounds of the invention by positron emission tomography (PET).
    Type: Application
    Filed: February 15, 2018
    Publication date: January 9, 2020
    Inventors: Yiyun Huang, Zhengxin Cai, Songye Li, Nabeel Nabulsi, Richard Carson
  • Radioligands for imaging the LPA-1 receptor
    Patent number: 9987381
    Abstract: The present invention relates to radiolabeled LPA1 receptor antagonists or pharmaceutically acceptable salts thereof which are useful for the quantitative imaging of LPA1 receptors in mammals.
    Type: Grant
    Filed: October 31, 2014
    Date of Patent: June 5, 2018
    Assignees: BRISTOL-MYERS SQUIBB COMPANY, YALE UNIVERSITY
    Inventors: Thomas Jon Seiders, David J. Donnelly, Samuel J. Bonacorsi, Jr., Kai Cao, Tritin Tran, Adrienne Pena, Joonyoung Kim, Richard E. Carson, Nabeel Nabulsi, Jean-Dominique Gallezot, Yiyun Huang, Jeffrey Roger Roppe
  • Antiseptic derivatives with broad spectrum antimicrobial activity for the impregnation of surfaces
    Patent number: 7713472
    Abstract: The present invention provides novel broad spectrum antiseptic compounds that further have properties that allow them to be coated/impregnated into polymer surfaces. Methods for coating these antiseptic compounds onto medical devices especially in-dwelling medical devices to prevent the growth of pathogens in such devices and hence, to prevent infection to patients via such devices are provided. The invention also provides antiseptics that are useful as general surface disinfectants and sterilizers, fluid disinfectants and biocide preservatives.
    Type: Grant
    Filed: January 11, 2002
    Date of Patent: May 11, 2010
    Assignee: Board of Regents, The University of Texas System
    Inventors: Issam Raad, Hend A. Hanna, Nabeel Nabulsi
  • Medical devices with broad spectrum antimicrobial activity
    Patent number: 7651661
    Abstract: The present invention provides novel broad spectrum antiseptic compounds that further have properties that allow them to be coated/impregnated into polymer surfaces. Methods for coating these antiseptic compounds onto medical devices especially indwelling medical devices to prevent the growth of pathogens in such devices and hence, to prevent infection to patients via such devices are provided. The invention also provides antiseptics that are useful as general surface disinfectants and sterilizers, fluid disinfectants and biocide preservatives.
    Type: Grant
    Filed: October 19, 2007
    Date of Patent: January 26, 2010
    Assignee: Board of Regents, the University of Texas System
    Inventors: Issam Raad, Hend A. Hanna, Nabeel Nabulsi
  • MEDICAL DEVICES WITH BROAD SPECTRUM ANTIMICROBIAL ACTIVITY
    Publication number: 20080183152
    Abstract: The present invention provides novel broad spectrum antiseptic compounds that further have properties that allow them to be coated/impregnated into polymer surfaces. Methods for coating these antiseptic compounds onto medical devices especially indwelling medical devices to prevent the growth of pathogens in such devices and hence, to prevent infection to patients via such devices are provided. The invention also provides antiseptics that are useful as general surface disinfectants and sterilizers, fluid disinfectants and biocide preservatives.
    Type: Application
    Filed: October 19, 2007
    Publication date: July 31, 2008
    Inventors: Issam Raad, Hend A. Hanna, Nabeel Nabulsi
  • Novel antiseptic derivatives with broad spectrum antimicrobial activity for the impregnation of surfaces
    Publication number: 20030078242
    Abstract: The present invention provides novel broad spectrum antiseptic compounds that further have properties that allow them to be coated/impregnated into polymer surfaces. Methods for coating these antiseptic compounds onto medical devices especially in-dwelling medical devices to prevent the growth of pathogens in such devices and hence, to prevent infection to patients via such devices are provided. The invention also provides antiseptics that are useful as general surface disinfectants and sterilizers, fluid disinfectants and biocide preservatives.
    Type: Application
    Filed: January 11, 2002
    Publication date: April 24, 2003
    Applicant: Board of Regents, The University of Texas System
    Inventors: Issam Raad, Hend A. Hanna, Nabeel Nabulsi