Abstract: The present invention concerns methods and apparatus for compartmentalizing and carrying out hemostasis of a massively bleeding internal bodily organ of a patient. Generally, the apparatus includes a flexible compartment-defining structure having physical dimensions sufficient to generally conform to the gross geometry of a substantial portion of the organ. The flexible compartment-defining structure has an inner and outer surface, and is configurable so as surround and compartmentalize a substantial portion of the organ, with the inner surface facing the external surface of the organ. The apparatus of the present invention can be used to carry out hemostasis and/or the collection of blood for reprocessing and subsequent introduction to the patient by auto-transfusion. In another embodiment of the present invention, apparatus manipulates the surface-temperature of an internal bodily organ is also provided.