Patents by Inventor Nadège DUMOULIN

Nadège DUMOULIN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Microorganisms with improved 1,3-propanediol and butyric acid production
    Patent number: 11814663
    Abstract: The present invention concerns a new mutant strain of Clostridium acetobutylicum comprising attenuated glycerol kinase activity. In addition, the present invention concerns a consortium of Clostridium comprising at least said mutant strain and at least one other species of Clostridium chosen among C. sporogenes and C. sphenoides. As this modified strain may be adapted for growth and for the production of 1,3-propanediol in an appropriate culture medium with high glycerol content, the invention also relates to a method for the production of 1,3-propanediolandbutyric acid, by culturing at least this mutant strain in an appropriate culture medium.
    Type: Grant
    Filed: August 9, 2019
    Date of Patent: November 14, 2023
    Assignee: METABOLIC EXPLORER
    Inventors: Wanda Dischert, Céline Raynaud, Laurence Dumon-Seignovert, Nadège Dumoulin
  • Microorganism and method for improved 1,3-propanediol production by fermentation on a culture medium with high glycerine content
    Patent number: 11655486
    Abstract: The present invention concerns a new method for the production of 1,3-propanediol comprising culturing a recombinant microorganism converting glycerol into 1,3-propanediol and overexpressing the hcpR and/or frdX gene on a medium comprising glycerine. A recombinant microorganism for the production of 1,3 propanediol from glycerol, wherein said microorganism converts glycerol into 1,3-propanediol and 10 overexpresses the hcpR and/or the frdX gene.
    Type: Grant
    Filed: August 3, 2018
    Date of Patent: May 23, 2023
    Assignee: METABOLIC EXPLORER
    Inventors: Céline Raynaud, Olivier Tourrasse, Nadège Dumoulin
  • MICROORGANISMS WITH IMPROVED 1,3-PROPANEDIOL AND BUTYRIC ACID PRODUCTION
    Publication number: 20210254108
    Abstract: The present invention concerns a new mutant strain of Clostridium acetobutylicum comprising attenuated glycerol kinase activity. In addition, the present invention concerns a consortium of Clostridium comprising at least said mutant strain and at least one other species of Clostridium chosen among C. sporogenes and C. sphenoides. As this modified strain may be adapted for growth and for the production of 1,3-propanediol in an appropriate culture medium with high glycerol content, the invention also relates to a method for the production of 1,3-propanediol and butyric acid, by culturing at least this mutant strain in an appropriate culture medium.
    Type: Application
    Filed: August 9, 2019
    Publication date: August 19, 2021
    Applicant: METABOLIC EXPLORER
    Inventors: Wanda DISCHERT, Céline RAYNAUD, Laurence DUMON-SEIGNOVERT, Nadège DUMOULIN
  • MICROORGANISM AND METHOD FOR IMPROVED 1,3-PROPANEDIOL PRODUCTION BY FERMENTATION ON A CULTURE MEDIUM WITH HIGH GLYCERINE CONTENT
    Publication number: 20200370072
    Abstract: The present invention concerns a new method for the production of 1,3-propanediol comprising culturing a recombinant microorganism converting glycerol into 1,3-propanediol and overexpressing the hcpR and/or frdX gene on a medium comprising glycerine. A recombinant microorganism for the production of 1,3 propanediol from glycerol, wherein said microorganism converts glycerol into 1,3-propanediol and 10 overexpresses the hcpR and/or the frdX gene.
    Type: Application
    Filed: August 3, 2018
    Publication date: November 26, 2020
    Applicant: METABOLIC EXPLORER
    Inventors: Céline RAYNAUD, Olivier TOURRASSE, Nadège DUMOULIN