Patents by Inventor Nada Slakeski

Nada Slakeski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PREVENTION, TREATMENT AND DIAGNOSIS OF P.GINGIVALIS INFECTION
    Publication number: 20230374081
    Abstract: The invention relates to generation and use of cellular and humoral responses for the prevention and treatment of P. gingivalis related conditions and diseases.
    Type: Application
    Filed: January 9, 2023
    Publication date: November 23, 2023
    Applicant: ORAL HEALTH AUSTRALIA PTY LTD
    Inventors: Eric Charles REYNOLDS, Neil Martin O`BRIEN SIMPSON, Keith J. CROSS, Nada SLAKESKI
  • Antibodies for prevention, treatment and diagnosis of infection
    Patent number: 11572391
    Abstract: Disclosed are P. gingivalis antibodies raised against a chimeric or fusion protein, wherein the chimeric or fusion protein comprises a first peptide joined directly or through a linker to a second peptide or polypeptide, wherein (A) the first peptide comprises a region of a P. gingivalis trypsin-like enzyme and (B) the second peptide or polypeptide comprises an adhesin domain of P. gingivalis.
    Type: Grant
    Filed: November 13, 2020
    Date of Patent: February 7, 2023
    Assignee: Oral Health Australia PTY Ltd
    Inventors: Eric Charles Reynolds, Neil Martin O'Brien Simpson, Keith J. Cross, Nada Slakeski
  • PREVENTION, TREATMENT AND DIAGNOSIS OF P.GINGIVALIS INFECTION
    Publication number: 20210079047
    Abstract: The invention relates to generation and use of cellular and humoral responses for the prevention and treatment of P. gingivalis related conditions and diseases.
    Type: Application
    Filed: November 13, 2020
    Publication date: March 18, 2021
    Applicant: Oral Health Australia PTY Ltd
    Inventors: Eric Charles REYNOLDS, Neil Martin O'BRIEN SIMPSON, Keith J. CROSS, Nada SLAKESKI
  • Methods of preparing antibodies
    Patent number: 10851138
    Abstract: Disclosed are methods related to the generation and use of cellular and humoral responses for the prevention and treatment of P. gingivalis related conditions and diseases, such as methods of preparing P. gingivalis antibodies, comprising immunizing a non-human animal with a chimeric or fusion protein, wherein the protein comprises a first peptide joined directly or through a linker to a second peptide or polypeptide, wherein (A) the first peptide comprises a region of a P. gingivalis trypsin-like enzyme and (B) the second peptide or polypeptide comprises an adhesin domain of P. gingivalis.
    Type: Grant
    Filed: September 18, 2018
    Date of Patent: December 1, 2020
    Assignee: ORAL HEALTH AUSTRALIA PTY LTD
    Inventors: Eric Charles Reynolds, Neil Martin O'Brien Simpson, Keith J Cross, Nada Slakeski
  • PREVENTION, TREATMENT AND DIAGNOSIS OF P.GINGIVALIS INFECTION
    Publication number: 20190194263
    Abstract: The invention relates to generation and use of cellular and humoral responses for the prevention and treatment of P. gingivalis related conditions and diseases.
    Type: Application
    Filed: September 18, 2018
    Publication date: June 27, 2019
    Applicant: Oral Health Australia PTY Ltd
    Inventors: Eric Charles REYNOLDS, Neil Martin O'BRIEN SIMPSON, Keith J. CROSS, Nada SLAKESKI
  • PREVENTION, TREATMENT AND DIAGNOSIS OF P.GINGIVALIS INFECTION
    Publication number: 20170247420
    Abstract: The invention relates to generation and use of cellular and humoral responses for the prevention and treatment of P. gingivalis related conditions and diseases.
    Type: Application
    Filed: December 6, 2016
    Publication date: August 31, 2017
    Applicant: Oral Health Australia Pty Ltd.
    Inventors: Eric Charles Reynolds, Neil Martin O'Brien Simpson, Keith J. Cross, Nada Slakeski
  • Prevention, treatment and diagnosis of infection
    Patent number: 9518109
    Abstract: The invention relates to generation and use of cellular and humoral responses for the prevention and treatment of P. gingivalis related conditions and diseases.
    Type: Grant
    Filed: September 16, 2014
    Date of Patent: December 13, 2016
    Assignee: ORAL HEALTH AUSTRALIA PTY LTD
    Inventors: Eric Charles Reynolds, Neil Martin O'Brien Simpson, Keith J Cross, Nada Slakeski
  • PREVENTON, TREATMENT AND DIAGNOSIS OF P. GINGIVALIS INFECTION
    Publication number: 20150079095
    Abstract: The invention relates to generation and use of cellular and humoral responses for the prevention and treatment of P. gingivalis related conditions and diseases.
    Type: Application
    Filed: September 16, 2014
    Publication date: March 19, 2015
    Applicant: Oral Health Australia PTY Ltd
    Inventors: Eric Charles Reynolds, Neil Martin O'Brien Simpson, Keith J. Cross, Nada Slakeski
  • Prevention, treatment and diagnosis of infection
    Patent number: 8871213
    Abstract: The invention relates to generation and use of cellular and humoral responses for the prevention and treatment of P. gingivalis related conditions and diseases.
    Type: Grant
    Filed: August 28, 2009
    Date of Patent: October 28, 2014
    Assignee: Oral Health Australia Pty Ltd
    Inventors: Eric Charles Reynolds, Neil Martin O'Brien Simpson, Keith J Cross, Nada Slakeski
  • Synthetic peptide constructs for the diagnosis and treatment of periodontis associated with
    Patent number: 8841420
    Abstract: The present invention relates to an oral composition and an immunogenic composition for the suppression of the pathogenic effects of the intra-oral bacterium Porphyromonas gingivalis associated with periodontal disease.
    Type: Grant
    Filed: March 28, 2013
    Date of Patent: September 23, 2014
    Assignee: The University of Melbourne
    Inventors: Eric Charles Reynolds, Neil Martin O'Brien-Simpson, Nada Slakeski
  • antigenic composition
    Patent number: 8784831
    Abstract: The present invention provides an antigenic composition, the composition comprising at least one recombinant protein. The recombinant protein comprises at least one epitope. The epitope is reactive with an antibody which is reactive with a polypeptide having the sequence set out in SEQ. ID. NO. 3 or SEQ. ID. NO. 5. The invention also provides methods and compositions for the production of the recombinant protein. Also provided are methods for the diagnosis, treatment and prevention of P. gingivalis infection.
    Type: Grant
    Filed: August 3, 2012
    Date of Patent: July 22, 2014
    Assignees: CSL Limited, The University of Melbourne
    Inventors: Eric Charles Reynolds, Nada Slakeski, Chao Guang Chen, Ian George Barr
  • SYNTHETIC PEPTIDE CONSTRUCTS FOR THE DIAGNOSIS AND TREATMENT OF PERIODONTIS ASSOCIATED WITH PORPHYROMONAS GINGIVALIS
    Publication number: 20130309179
    Abstract: The present invention relates to an oral composition and an immunogenic composition for the suppression of the pathogenic effects of the intra-oral bacterium Porphyromonas gingivalis associated with periodontal disease.
    Type: Application
    Filed: March 28, 2013
    Publication date: November 21, 2013
    Applicant: The University of Melbourne
    Inventors: Eric Charles Reynolds, Neil Martin O'BRIEN-SIMPSON, Nada SLAKESKI
  • P. GINGIVALIS ANTIGENIC COMPOSITION
    Publication number: 20130164298
    Abstract: The present invention provides an antigenic composition, the composition comprising at least one recombinant protein. The recombinant protein comprises at least one epitope. The epitope is reactive with an antibody which is reactive with a polypeptide having the sequence set out in SEQ. ID. NO. 3 or SEQ. ID. NO. 5. The invention also provides methods and compositions for the production of the recombinant protein. Also provided are methods for the diagnosis, treatment and prevention of P. gingivalis infection.
    Type: Application
    Filed: August 3, 2012
    Publication date: June 27, 2013
    Inventors: Eric Charles Reynolds, Nada Slakeski, Chao Guang Chen, Ian George Barr
  • Synthetic peptide constructs for the diagnosis and treatment of Periodontitis associated with
    Patent number: 8431688
    Abstract: The present invention relates to an oral composition and an immunogenic composition for the suppression of the pathogenic effects of the intra-oral bacterium Porphyromonas gingivalis associated with periodontal disease.
    Type: Grant
    Filed: June 9, 2010
    Date of Patent: April 30, 2013
    Assignee: The University of Melbourne
    Inventors: Eric C. Reynolds, Neil Martin O'Brien-Simpson, Nada Slakeski
  • antigenic composition
    Patent number: 8282933
    Abstract: The present invention provides an antigenic composition, the composition comprising at least one recombinant protein. The recombinant protein comprises at least one epitope. The epitope is reactive with an antibody which is reactive with a polypeptide having the sequence set out in SEQ. ID. NO. 3 or SEQ. ID. NO. 5. The invention also provides methods and compositions for the production of the recombinant protein. Also provided are methods for the diagnosis, treatment and prevention of P. gingivalis infection.
    Type: Grant
    Filed: March 27, 2007
    Date of Patent: October 9, 2012
    Assignee: CSL Limited
    Inventors: Eric C. Reynolds, Nada Slakeski, Guang Gao Chen, George Ian Barr
  • PREVENTION, TREATMENT AND DIAGNOSIS OF P.GINGIVALIS INFECTION
    Publication number: 20110280880
    Abstract: The invention relates to generation and use of cellular and humoral responses for the prevention and treatment of P. gingivalis related conditions and diseases.
    Type: Application
    Filed: August 28, 2009
    Publication date: November 17, 2011
    Inventors: Eric Charles Reynolds, Neil Martin O'Brien Simpson, Keith J. Cross, Nada Slakeski
  • SYNTHETIC PEPTIDE CONSTRUCTS FOR THE DIAGNOSIS AND TREATMENT OF PERIODONTITIS ASSOCIATED WITH PORPHYROMONAS GINGIVALIS
    Publication number: 20110268670
    Abstract: The present invention relates to an oral composition and an immunogenic composition for the suppression of the pathogenic effects of the intra-oral bacterium Porphyromonas gingivalis associated with periodontal disease.
    Type: Application
    Filed: June 9, 2010
    Publication date: November 3, 2011
    Inventors: Eric Charles Reynolds, Neil Martin O'Brien-Simpson, Nada Slakeski
  • Diagnostics and treatments of periodontal disease
    Publication number: 20110213129
    Abstract: This invention relates to the PrtR-PrtK cell surface protein of Porphyromonas gingivalis and in particular a multimeric cell association protein complex comprising the PrtR and PrtK proteins. Accordingly the invention provides a substantially purified antigenic complex for use in raising an antibody response directed against Porphyromonas gingivalis. The complex comprises at least one multimeric protein complex of arginine-specific and lysine-specific thiol endopeptidases each containing at least one adhesin domain, the complex having a molecular weight of greater than about 200 kDa. The invention also relates to pharmaceutical compositions and associated agents based on said complex for the detection, prevention and treatment of Periodontal disease associated with P. gingivalis.
    Type: Application
    Filed: March 16, 2011
    Publication date: September 1, 2011
    Applicant: The University of Melbourne
    Inventors: Eric Charles Reynolds, Peter Singh Bhogal, Nada Slakeski
  • Synthetic peptide constructs for the diagnosis and treatment of periodontitis associated with
    Patent number: 7749502
    Abstract: The present invention relates to an oral composition and an immunogenic composition for the suppression of the pathogenic effects of the intra-oral bacterium Porphyromonas gingivalis associated with periodontal disease.
    Type: Grant
    Filed: March 30, 2007
    Date of Patent: July 6, 2010
    Assignee: The University of Melbourne
    Inventors: Eric C. Reynolds, Neil Martin O'Brien-Simpson, Nada Slakeski
  • antigenic composition
    Patent number: 7419671
    Abstract: The present invention provides an antigenic composition, the composition comprising at least one recombinant protein. The recombinant protein comprises at least one epitope. The epitope is reactive with an antibody which is reactive with a polypeptide having the sequence set out in SEQ. ID. NO. 3 or SEQ. ID. NO. 5. The invention also provides methods and compositions for the production of the recombinant protein. Also provided are methods for the diagnosis, treatment and prevention of P. gingivalis infection.
    Type: Grant
    Filed: June 18, 2002
    Date of Patent: September 2, 2008
    Assignees: CSL Limited, The University of Melbourne
    Inventors: Eric Charles Reynolds, Nada Slakeski, Chao Guang Chen, Ian George Barr