Patents by Inventor Nadav Agian
Nadav Agian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220296370Abstract: Apparatus and methods are described including a valve frame (20) configured to support a prosthetic valve within a native atrio-ventricular valve. The valve frame (20) includes an atrial part (26) and a cylindrical part (22), to which the prosthetic valve leaflets (23) are coupled. A plurality of chord-recruiting arms (24) extend at least radially from the ventricular end of the cylindrical part (22). The chord-recruiting arms (24) are coupled to the ventricular end of the cylindrical part via stitches (82), and the stitches (82) are configured to act as hinges, such that upon being released from a radially-constrained configuration, while the cylindrical part (22) is held in an at least partially radially-constrained configuration, the chord-recruiting arms (24) are configured to extend radially outwardly by pivoting about the stitches (82) with respect to the cylindrical part (22). Other applications are also described.Type: ApplicationFiled: August 13, 2020Publication date: September 22, 2022Inventors: Nadav Agian, Shai Karni, Amit Tubishevitz, Yuri Sudin
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Publication number: 20220015900Abstract: Apparatus and methods are described including rotating at least a portion of a valve frame in a first direction and subsequently rotating the valve frame in a second direction. The valve frame includes chord-recruiting arms. An outer surface of each of the chord-recruiting arms has a smooth, convex curvature that extends along substantially a full length of the chord-recruiting arm, such that during the rotation of the portion of the valve frame in the first direction, the chords slide over the outer surface of the chord-recruiting arm without be recruited or caught by the chord-recruiting arm. An inner surface of each of the chord-recruiting arms has a concave curvature, such that during the rotation of the portion of the valve frame in the second direction, the chords are recruited within a space defined by the concave curvature.Type: ApplicationFiled: September 29, 2021Publication date: January 20, 2022Inventors: Nadav Agian, Shai Karni, Amit Tubishevitz, Yuri Sudin
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Publication number: 20220015896Abstract: Apparatus and methods are described including a valve frame configured to support a prosthetic valve within a native atrio-ventricular valve. The valve frame includes an atrial part comprising a disc-shaped portion configured to be deployed on an atrial side of the valve annulus, and a frustoconical portion, and a cylindrical part to which the prosthetic valve leaflets are coupled. The cylindrical part configured to be deployed such that a ventricular end of the cylindrical part is disposed within the ventricle. A plurality of protruding struts are configured to protrude from outside the cylindrical part, the frustoconical portion of the atrial part being coupled to the cylindrical part via the protruding struts. Other applications are also described.Type: ApplicationFiled: September 29, 2021Publication date: January 20, 2022Inventors: Nadav Agian, Shai Karni, Amit Tubishevitz, Yuri Sudin
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Patent number: 11160506Abstract: This invention relates to an implantable device for a physiologic sensor, comprising an implantable expandable anchor, a bridge on which the sensor is secured, as well as an optional adapting ring. The invention also relates to a method of monitoring bodily functions using the anchor and sensor. The anchor is compressed and the bridge assumes an elongated shape during delivery to a target lumen. Upon deployment at the target site, the anchor expands and the bridge bows into the interior lumen of the expanded anchor, distancing the sensor from the vessel wall. This invention also relates to a method of manufacturing said device and a method of implanting a sensor.Type: GrantFiled: February 20, 2019Date of Patent: November 2, 2021Assignee: Microtech Medical Technologies LtdInventors: Yekaterina Dlugach, Nadav Agian
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Publication number: 20190175105Abstract: This invention relates to an implantable device for a physiologic sensor, comprising an implantable expandable anchor, a bridge on which the sensor is secured, as well as an optional adapting ring. The invention also relates to a method of monitoring bodily functions using the anchor and sensor. The anchor is compressed and the bridge assumes an elongated shape during delivery to a target lumen. Upon deployment at the target site, the anchor expands and the bridge bows into the interior lumen of the expanded anchor, distancing the sensor from the vessel wall. This invention also relates to a method of manufacturing said device and a method of implanting a sensor.Type: ApplicationFiled: February 20, 2019Publication date: June 13, 2019Inventors: Yekaterina DLUGACH, Nadav AGIAN
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Patent number: 10238339Abstract: This invention relates to an implantable device for a physiologic sensor, comprising an implantable expandable anchor, a bridge on which the sensor is secured, as well as an optional adapting ring. The invention also relates to a method of monitoring bodily functions using the anchor and sensor. The anchor is compressed and the bridge assumes an elongated shape during delivery to a target lumen. Upon deployment at the target site, the anchor expands and the bridge bows into the interior lumen of the expanded anchor, distancing the sensor from the vessel wall. This invention also relates to a method of manufacturing said device and a method of implanting a sensor.Type: GrantFiled: March 14, 2014Date of Patent: March 26, 2019Assignee: Microtech Medical Technologies Ltd.Inventors: Yekaterina Dlugach, Nadav Agian
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Publication number: 20150038911Abstract: An adapter (50) for achieving intradennal dosed delivery of a liquid by use of a dosed drug delivery device including a reservoir having a pierceable septum, the adapter having a connector including an attachment configuration (22) for sliding a recess of the adapter onto a projection of the dosed drug delivery device and a hollow needle (25) deployed for piercing the septum. At least one microneedle (10) projects from the connector. A flow path arrangement (28) interconnects the needle and the hollow microneedle(s). The recess is shaped to restrict the microneedle(s) to only a finite number of rotational orientations relative to the axis of the device. The connector and/or the needle is adapted for application of a sealant to prevent leakage of the liquid.Type: ApplicationFiled: January 24, 2013Publication date: February 5, 2015Applicant: NANOPASS TECHNOLOGIES LTDInventors: Yotam Levin, Yehoshua Yeshurun, Nadav Agian, Barak Panga, Yoel sefi, Gal Admati
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Publication number: 20140275865Abstract: The device and method of the invention generally relate to a system and method for percutaneous delivery, implantation and securement of an anchor at a target site. The system comprises an anchor having a bridge, a first stabilizer having a crimped state and a deployed state, a second stabilizer having a crimped state and a deployed state, and a positioning arm. The system may further comprise a cannula, pushrod, and sheath. The system permits the deposit of an anchor at a target location in the body by utilizing a controlled amount of force. The anchors and methods are particularly well-suited to implantation within the body of a living animal or human to monitor various physiological conditions.Type: ApplicationFiled: July 3, 2013Publication date: September 18, 2014Inventors: Eric S. TAMMAM, Oleg WEIZMAN, Yekaterina DLUGACH, Nadav AGIAN
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Publication number: 20140276141Abstract: This invention relates to an implantable device for a physiologic sensor, comprising an implantable expandable anchor, a bridge on which the sensor is secured, as well as an optional adapting ring. The invention also relates to a method of monitoring bodily functions using the anchor and sensor. The anchor is compressed and the bridge assumes an elongated shape during delivery to a target lumen. Upon deployment at the target site, the anchor expands and the bridge bows into the interior lumen of the expanded anchor, distancing the sensor from the vessel wall. This invention also relates to a method of manufacturing said device and a method of implanting a sensor.Type: ApplicationFiled: March 14, 2014Publication date: September 18, 2014Applicant: MICROTECH MEDICAL TECHNOLOGIES LTD.Inventors: Yekaterina DLUGACH, Nadav AGIAN
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Publication number: 20110282298Abstract: An injection system applicable to off-the-shelf syringes having a microneedle hub may reduce dead space and isolate the drug fluid from the microneedle chip to avoid compatibility issues. An insert may be disposed inside a male luer fitting and extend so that it is also disposed inside the female luer fitting using an insert. A septum may isolate the drug fluid from the microneedle chip in the hub prior to activation and the septum may, after activation, seal the triangular space in the hub to prevent leakage of fluid back to the syringe.Type: ApplicationFiled: December 9, 2009Publication date: November 17, 2011Inventors: Nadav Agian, Yonni Shem-Tov, Barak Panga, Yoel Sefi, Yotam Levin
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Publication number: 20110238038Abstract: An intradermal mini-needle interface has a penetration limiter providing a skin contact edge and a hollow hypodermic needle having a beveled penetrating portion protruding forward beyond the skin contact edge by no more than 3 mm. At least one skin contact surface defines a skin contact plane parallel to, or at a shallow angle to, the needle axis. The skin contact plane intersects the skin contact edge substantially at a base of the penetrating portion. Preferably, the penetration limiter is asymmetric under rotation about the needle axis.Type: ApplicationFiled: December 3, 2009Publication date: September 29, 2011Applicant: Nanopass Technologies Ltd.Inventors: Yoel Sefi, Yotam Levin, Yehoshua Yeshurun, Nadav Agian