Patents by Inventor Nadav Ahituv

Nadav Ahituv has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS INVOLVING ADGRG6
    Publication number: 20250367321
    Abstract: The present disclosure provides compositions and methods for reducing body fat in a human male subject by mutating or reducing the expression of the Adgrg6 gene in one or more cells of the human male subject.
    Type: Application
    Filed: June 23, 2023
    Publication date: December 4, 2025
    Applicant: The Regents of the University of California
    Inventors: Nadav Ahituv, Hai Nguyen
  • GENE THERAPY FOR HAPLOINSUFFICIENCY
    Publication number: 20250228980
    Abstract: Methods and compositions are provided for activating transcription in a mammalian cell.
    Type: Application
    Filed: April 4, 2025
    Publication date: July 17, 2025
    Applicants: The Regents of The University of California, The Regents of The University of California
    Inventors: Nadav Ahituv, Navneet Matharu
  • Gene therapy for haploinsufficiency
    Patent number: 12285496
    Abstract: Methods and compositions are provided for activating transcription in a mammalian cell.
    Type: Grant
    Filed: October 11, 2022
    Date of Patent: April 29, 2025
    Assignee: The Regents of the University of California
    Inventors: Nadav Ahituv, Navneet Matharu
  • COMPOSITIONS COMPRISING NULLOMERS AND METHODS OF USING THE SAME FOR CANCER DETECTION AND DIAGNOSIS
    Publication number: 20240229157
    Abstract: The present disclosure provides methods and compositions for the detection, identification, classification and characterization of cancer in general and cancer types in biological material. Sequences that are not found in the human reference genome or any set of genomic tiled regions, termed nullomers, which can resurface due to mutations, serve as biomarkers and are predictive of cancer. The invention also enables the identification of cancer subtype and the stratification of patients based on sample-specific vulnerabilities guiding treatment choice. For coding nullomers it also covers their use as neoantigens. The algorithms presented hereby can be applied to biological material including biopsy, cell-free DNA samples and RNA samples.
    Type: Application
    Filed: May 3, 2022
    Publication date: July 11, 2024
    Inventors: Nadav AHITUV, Ofer YIZHAR-BARNEA, Ilias GEORGAKOPOUOS-SOARES, Ioannis MOURATIDIS, Martin HEMBERG
  • GENE THERAPY FOR HAPLOINSUFFICIENCY
    Publication number: 20230293729
    Abstract: Methods and compositions are provided for activating transcription in a mammalian cell.
    Type: Application
    Filed: October 11, 2022
    Publication date: September 21, 2023
    Applicant: The Regents of the University of California
    Inventors: Nadav Ahituv, Navneet Matharu
  • Gene therapy for haploinsufficiency
    Patent number: 11730828
    Abstract: Methods and compositions are provided for activating transcription in a mammalian cell.
    Type: Grant
    Filed: February 7, 2018
    Date of Patent: August 22, 2023
    Assignee: The Regents of the University of California
    Inventors: Nadav Ahituv, Navneet Matharu
  • GENE THERAPY FOR HAPLOINSUFFICIENCY
    Publication number: 20190351074
    Abstract: Methods and compositions are provided for activating transcription in a mammalian cell.
    Type: Application
    Filed: February 7, 2018
    Publication date: November 21, 2019
    Inventors: Nadav Ahituv, Navneet Matharu