Abstract: An imaging system includes a visible light source configured to output visible light and a near infrared laser light source configured to output an excitation laser light. The system also includes a camera assembly having: a housing with an opening configured to receive a combined light, which includes visible light and infrared fluorescence light. The combined light entering the housing along a combined light path, the combined light may include visible light and infrared fluorescence light; an aperture mechanism having an adjustable opening disposed along the combined light path; a beamsplitter configured to split the combined light into the visible light along a visible light path and the infrared fluorescence light along an infrared light path; a visible light sensor configured to receive the visible light and to generate visible light image data; and an infrared sensor configured to receive the infrared fluorescence light and to generate infrared fluorescence image data.

Abstract: An endoscope camera assembly includes a housing having an opening configured to couple to an endoscope and to receive a combined light entering the housing along a combined light path. The combined light includes visible light and infrared fluorescence light. The camera assembly includes a cold mirror configured to split the combined light into the visible light along a visible light path and the infrared fluorescence light along an infrared light path. The camera assembly also includes a visible light sensor configured to receive the visible light and to generate visible light image data. The camera assembly further includes an infrared sensor configured to receive the infrared fluorescence light and to generate infrared fluorescence image data.

Abstract: A device and method for fluorescent imaging may include an imaging unit including a fluorescent camera with an optical detector that is configured to acquire a fluorescent image of a fluorescing sample, the image including raw pixel values. A user interface may display an image formed from display image pixels derived from the raw image pixels. A distance sensor may measure a distance to the fluorescing sample. A distance between the optical detector and fluorescing sample may be determined from the measured distance. A processing unit may obtain a gain value, match the determined distance to a distance value associated a respective gain range, and impose limits of the gain values range onto the gain value, to determine a limited gain value. The limited gain value may be applied to the raw image pixels, thereby deriving display image pixels.

Abstract: A device and method for fluorescent imaging may include an imaging unit including a fluorescent camera with an optical detector that is configured to acquire a fluorescent image of a fluorescing sample, the image including raw pixel values. A user interface may display an image formed from display image pixels derived from the raw image pixels. A distance sensor may measure a distance to the fluorescing sample. A distance between the optical detector and fluorescing sample may be determined from the measured distance. A processing unit may obtain a gain value, match the determined distance to a distance value associated a respective gain range, and impose limits of the gain values range onto the gain value, to determine a limited gain value. The limited gain value may be applied to the raw image pixels, thereby deriving display image pixels.

Abstract: Stereoscopic device including an image directing assembly, an image differentiator and an image detector, the image directing assembly having a first light inlet for receiving a first image and a second light inlet for receiving a second image, the first light inlet being spaced apart from the second light inlet, the image differentiator differentiating between the first image and the second image, wherein the image directing assembly directs the first image to the image detector via a common path, and wherein the image directing assembly directs the second image to the image detector via the common path.

Abstract: Stereoscopic device including an image directing assembly, an image differentiator and an image detector, the image directing assembly having a first light inlet for receiving a first image and a second light inlet for receiving a second image, the first light inlet being spaced apart from the second light inlet, the image differentiator differentiating between the first image and the second image, wherein the image directing assembly directs the first image to the image detector via a common path, and wherein the image directing assembly directs the second image to the image detector via the common path.

Abstract: Stereoscopic device including an image directing assembly, an image differentiator and an image detector, the image directing assembly having a first light inlet for receiving a first image and a second light inlet for receiving a second image, the first light inlet being spaced apart from the second light inlet, the image differentiator differentiating between the first image and the second image, wherein the image directing assembly directs the first image to the image detector via a common path, and wherein the image directing assembly directs the second image to the image detector via the common path.

Abstract: Stereoscopic device including an image directing assembly, an image differentiator and an image detector, the image directing assembly having a first light inlet for receiving a first image and a second light inlet for receiving a second image, the first light inlet being spaced apart from the second light inlet, the image differentiator differentiating between the first image and the second image, wherein the image directing assembly directs the first image to the image detector via a common path, and wherein the image directing assembly directs the second image to the image detector via the common path.

Abstract: Stereoscopic device including an image directing assembly, an image differentiator and an image detector, the image directing assembly having a first light inlet for receiving a first image and a second light inlet for receiving a second image, the first light inlet being spaced apart from the second light inlet, the image differentiator differentiating between the first image and the second image, wherein the image directing assembly directs the first image to the image detector via a common path, and wherein the image directing assembly directs the second image to the image detector via the common path.

Abstract: Stereoscopic device including an image directing assembly, an image differentiator and an image detector, the image directing assembly having a first light inlet for receiving a first image and a second light inlet for receiving a second image, the first light inlet being spaced apart from the second light inlet, the image differentiator differentiating between the first image and the second image, wherein the image directing assembly directs the first image to the image detector via a common path, and wherein the image directing assembly directs the second image to the image detector via the common path.

Abstract: Stereoscopic device including an image directing assembly, an image differentiator and an image detector, the image directing assembly having a first light inlet for receiving a first image and a second light inlet for receiving a second image, the first light inlet being spaced apart from the second light inlet, the image differentiator differentiating between the first image and the second image, wherein the image directing assembly directs the first image to the image detector via a common path, and wherein the image directing assembly directs the second image to the image detector via the common path.

Abstract: Stereoscopic device including an image directing assembly, an image differentiator and an image detector, the image directing assembly having a first light inlet for receiving a first image and a second light inlet for receiving a second image, the first light inlet being spaced apart from the second light inlet, the image differentiator differentiating between the first image and the second image, wherein the image directing assembly directs the first image to the image detector via a common path, and wherein the image directing assembly directs the second image to the image detector via the common path.

Abstract: A method of analyzing particles for chemical or biological species. Spectral images of the particles are acquired. Targets are identified in the images and are classified according to morphology type and spectrum type. Each target is assigned a value of an extensive property. A descriptor vector is formed, each element of the descriptor vector being the sum of the extensive property values for one target class. The descriptor vector is transformed to a vector of mass concentrations of chemical species of interest, or of number concentrations of biological species of interest, using a relationship determined in a calibration procedure. In the calibration procedure, spectral images of calibration samples of known composition are acquired, and empirical morphology types and spectrum types are inferred from the spectral images. Targets are identified in the spectral images, classified according to morphology type and spectrum type, and assigned values of an extensive property.