Patents by Inventor Nadav Orr

Nadav Orr has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Subcutaneous administration of anti-hepatitis B antibodies
    Patent number: 9657087
    Abstract: The present application relates to an immunoglobulin preparation comprising anti-hepatitis B antibodies for subcutaneous administration and to uses thereof, including methods for treating, preventing and/or reducing a disease, disorder or condition associated with hepatitis B virus.
    Type: Grant
    Filed: June 17, 2014
    Date of Patent: May 23, 2017
    Assignee: Omrix Biopharmaceuticals Ltd.
    Inventors: Orgad Laub, Nadav Orr
  • METHOD FOR PURIFYING AND QUANTIFYING THROMBIN AND ITS DEGRADATION POLYPEPTIDES
    Publication number: 20160244739
    Abstract: Provided is a method for purifying ?-thrombin and for quantifying ?-thrombin and its degradation polypeptides in a liquid proteinatious solution. The method employs a one-step anion exchange chromatography method. The method allows purification and/or quantification of a homogenous post-translationally modified ?-thrombin. The method can also be used for purification and/or quantification of ?-thrombin.
    Type: Application
    Filed: February 24, 2016
    Publication date: August 25, 2016
    Inventors: TAMAR AUERBACH-NEVO, NADAV ORR, ISRAEL NUR
  • Immunoassay for thrombin detection
    Patent number: 9329183
    Abstract: The invention relates to an in vitro immunoassay for quantifying thrombin in a sample comprising anti-thrombin III (AT-III) and thrombin. The method comprises the following steps: contacting the sample with a small molecule that recognizes the substrate binding site of thrombin; contacting the thrombin with a thrombin specific antibody raised against a thrombin blocked in the active site; and measuring the level of bound antibody.
    Type: Grant
    Filed: May 12, 2015
    Date of Patent: May 3, 2016
    Assignee: Omrix Biopharmaceuticals Ltd.
    Inventors: Israel Nur, Nadav Orr, Roni Mintz
  • IMMUNOASSAY FOR THROMBIN DETECTION
    Publication number: 20150241430
    Abstract: The invention relates to an in vitro immunoassay for quantifying thrombin in a sample comprising anti-thrombin III (AT-III) and thrombin. The method comprises the following steps: contacting the sample with a small molecule that recognizes the substrate binding site of thrombin; contacting the thrombin with a thrombin specific antibody raised against a thrombin blocked in the active site; and measuring the level of bound antibody.
    Type: Application
    Filed: May 12, 2015
    Publication date: August 27, 2015
    Inventors: Israel Nur, Nadav Orr, Roni Mintz
  • Immunoassay for thrombin detection
    Patent number: 9057737
    Abstract: The invention relates to an in vitro immunoassay for quantifying thrombin in a sample comprising anti-thrombin III (AT-III) and thrombin. The method comprises the following steps: contacting the sample with a small molecule that recognizes the substrate binding site of thrombin; contacting the thrombin with a thrombin specific antibody raised against a thrombin blocked in the active site; and measuring the level of bound antibody.
    Type: Grant
    Filed: November 30, 2011
    Date of Patent: June 16, 2015
    Assignee: Omrix Biopharmaceuticals Ltd.
    Inventors: Roni Mintz, Nadav Orr, Israel Nur
  • COMPOUNDS AND METHODS FOR STABILIZING THROMBIN ACTIVITY
    Publication number: 20150118213
    Abstract: The present invention is directed to compounds useful in stabilizing thrombin activity, thrombin compositions comprising the compounds, methods of using the compounds and methods of identifying compounds capable of stabilizing thrombin activity. The compounds are preferably isolated peptides comprising or interacting with the gamma loop of thrombin.
    Type: Application
    Filed: October 21, 2014
    Publication date: April 30, 2015
    Inventors: Nadav Orr, Yair Pilpel, Sivan Doron
  • SUBCUTANEOUS ADMINISTRATION OF ANTI-HEPATITIS B ANTIBODIES
    Publication number: 20140294858
    Abstract: The present application relates to an immunoglobulin preparation comprising anti-hepatitis B antibodies for subcutaneous administration and to uses thereof, including methods for treating, preventing and/or reducing a disease, disorder or condition associated with hepatitis B virus
    Type: Application
    Filed: June 17, 2014
    Publication date: October 2, 2014
    Inventors: Orgad LAUB, Nadav ORR
  • Subcutaneous administration of anti-hepatitis B antibodies
    Patent number: 8795671
    Abstract: The present application relates to an immunoglobulin preparation comprising anti-hepatitis B antibodies for subcutaneous administration and to uses thereof, including methods for treating, preventing and/or reducing a disease, disorder or condition associated with hepatitis B virus.
    Type: Grant
    Filed: December 3, 2009
    Date of Patent: August 5, 2014
    Assignee: Omrix Biopharmaceuticals Ltd.
    Inventors: Orgad Laub, Nadav Orr
  • IMMUNOASSAY FOR THROMBIN DETECTION
    Publication number: 20120149030
    Abstract: The invention relates to an in vitro immunoassay for quantifying thrombin in a sample comprising anti-thrombin III (AT-III) and thrombin. The method comprises the following steps: contacting the sample with a small molecule that recognizes the substrate binding site of thrombin; contacting the thrombin with a thrombin specific antibody raised against a thrombin blocked in the active site; and measuring the level of bound antibody.
    Type: Application
    Filed: November 30, 2011
    Publication date: June 14, 2012
    Inventors: Roni Mintz, Nadav Orr, Israel Nur
  • Subcutaneous Administration of Anti-Hepatitis B Antibodies
    Publication number: 20100143378
    Abstract: The present application relates to an immunoglobulin preparation comprising anti-hepatitis B antibodies for subcutaneous administration and to uses thereof, including methods for treating, preventing and/or reducing a disease, disorder or condition associated with hepatitis B virus.
    Type: Application
    Filed: December 3, 2009
    Publication date: June 10, 2010
    Applicant: OMRIX Biopharmaceuticals Ltd.
    Inventors: Orgad LAUB, Nadav Orr
  • PRODUCTS FOR PROPHYLAXIS AND/OR TREATMENT OF VIRAL DISEASES AND METHODS OF MAKING AND USING SAME
    Publication number: 20100143377
    Abstract: The invention relates to an immunoglobulin composition suitable for prophylaxis and/or treatment of a viral mediated disease, disorder or condition and to methods of its preparation. In one embodiment, the invention provides a potent intravenous immunoglobulin composition useful for the treatment or prevention of a West Nile virus mediated disease, disorder or condition.
    Type: Application
    Filed: April 10, 2008
    Publication date: June 10, 2010
    Inventors: Orgad Laub, Israel Nur, Nadav Orr