Patents by Inventor Nader N. NASIEF ABDEL-SAYED

Nader N. NASIEF ABDEL-SAYED has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Acetamido-phenyltetrazole derivatives and methods of using the same
    Patent number: 11739089
    Abstract: The present disclosure relates to compounds of Formula (IA) and to their prodrugs, pharmaceutically acceptable salts, pharmaceutical compositions, methods of use, and methods for their preparation. The compounds disclosed herein are useful for the treatment of disorders in which P-glycoprotein and/or cytochrome P450 (e.g. CYP3A4) is modulated (e.g., cancers which have developed multi-drug resistance).
    Type: Grant
    Filed: October 7, 2021
    Date of Patent: August 29, 2023
    Assignee: Athenex, Inc.
    Inventors: Sameer Urgaonkar, Ahmed M. Said, Nader N. Nasief Abdel Sayed, Laura Beth Pitzonka, Murray John Cutler, Michael P. Smolinski, Johnson Yiu-Nam Lau
  • ACETAMIDO-PHENYLBENZAMIDE DERIVATIVES AND METHODS OF USING THE SAME
    Publication number: 20220106301
    Abstract: The present disclosure relates to compounds of Formula (I): and to their prodrugs, pharmaceutically acceptable salts, pharmaceutical compositions, methods of use, and methods for their preparation. The compounds disclosed herein are useful for the treatment of disorders in which expression of P-glycoprotein and/or cytochrome P450 (e.g., CYP3A4) is modulated (e.g., cancers which have developed multi-drug resistance).
    Type: Application
    Filed: October 7, 2021
    Publication date: April 7, 2022
    Inventors: Sameer URGAONKAR, Ahmed M. SAID, Nader N. NASIEF ABDEL SAYED, Laura Beth PITZONKA, Murray John CUTLER, Michael P. SMOLINSKI, Johnson Yiu-Nam LAU
  • ACETAMIDO-PHENYLTETRAZOLE DERIVATIVES AND METHODS OF USING THE SAME
    Publication number: 20220106312
    Abstract: The present disclosure relates to compounds of Formula (IA) and to their prodrugs, pharmaceutically acceptable salts, pharmaceutical compositions, methods of use, and methods for their preparation. The compounds disclosed herein are useful for the treatment of disorders in which P-glycoprotein and/or cytochrome P450 (e.g. CYP3A4) is modulated (e.g., cancers which have developed multi-drug resistance).
    Type: Application
    Filed: October 7, 2021
    Publication date: April 7, 2022
    Inventors: Sameer URGAONKAR, Ahmed M. SAID, Nader N. NASIEF ABDEL SAYED, Laura Beth PITZONKA, Murray John CUTLER, Michael P. SMOLINSKI, Johnson Yiu-Nam LAU
  • BIARYL COMPOSITIONS AND METHODS FOR MODULATING A KINASE CASCADE
    Publication number: 20210196724
    Abstract: The application relates to biaryl compounds, pharmaceutical compositions comprising the compounds, and methods of use the compounds for treating cell proliferation disorders.
    Type: Application
    Filed: March 1, 2021
    Publication date: July 1, 2021
    Inventors: Michael P. SMOLINSKI, Nader N. NASIEF ABDEL SAYED, David G. HANGAUER, JR.
  • Biaryl compositions and methods for modulating a kinase cascade
    Patent number: 10973828
    Abstract: The application relates to biaryl compounds, pharmaceutical compositions comprising the compounds, and methods of use the compounds for treating cell proliferation disorders.
    Type: Grant
    Filed: December 26, 2018
    Date of Patent: April 13, 2021
    Assignee: Athenex, Inc.
    Inventors: Michael P. Smolinski, Nader N. Nasief Abdel-Sayed, David G. Hangauer, Jr.
  • BIARYL COMPOSITIONS AND METHODS FOR MODULATING A KINASE CASCADE
    Publication number: 20190125754
    Abstract: The application relates to biaryl compounds, pharmaceutical compositions comprising the compounds, and methods of use the compounds for treating cell proliferation disorders.
    Type: Application
    Filed: December 26, 2018
    Publication date: May 2, 2019
    Inventors: Michael P. SMOLINSKI, Nader N. NASIEF ABDEL-SAYED, David G. HANGAUER, JR.
  • Biaryl compositions and methods for modulating a kinase cascade
    Patent number: 10213435
    Abstract: The application relates to biaryl compounds, pharmaceutical compositions comprising the compounds, and methods of use the compounds for treating cell proliferation disorders.
    Type: Grant
    Filed: August 14, 2017
    Date of Patent: February 26, 2019
    Assignee: Athenex, Inc.
    Inventors: Michael P. Smolinski, Nader N. Nasief Abdel-Sayed, David G. Hangauer, Jr.
  • BIARYL COMPOSITIONS AND METHODS FOR MODULATING A KINASE CASCADE
    Publication number: 20180042934
    Abstract: The application relates to biaryl compounds, pharmaceutical compositions comprising the compounds, and methods of use the compounds for treating cell proliferation disorders.
    Type: Application
    Filed: August 14, 2017
    Publication date: February 15, 2018
    Inventors: Michael P. SMOLINSKI, Nader N. NASIEF ABDEL-SAYED, David G. HANGAUER, JR.