Patents by Inventor Nadia Benkirane-Jessel

Nadia Benkirane-Jessel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITE PRODUCT FOR THE OSTEOARTICULAR REGENERATION OF CARTILAGE LESION
    Publication number: 20230256138
    Abstract: The present invention relates to a biomaterial comprising: —a membrane wound patch (a), made of a nanofibrous polymeric scaffold, —a hydrogel (b) including autologous or allogenic bone marrow-derived mesenchymal stem cells, and —a bone wound patch (c) being a nanofibrous scaffold made of polymers, wherein said scaffold has a surface coated with an interrupted coating made of multilayered droplets, said multilayered droplets being droplets composed of at least one layer pair consisting of a layer of polyanions and a layer of polycations, and wherein the bone wound patch (c) further comprises a bone growth factor; wherein the hydrogel (b) is included between the membrane wound patch (a) and the bone wound patch (c).
    Type: Application
    Filed: May 14, 2020
    Publication date: August 17, 2023
    Applicants: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), UNIVERSITÉ DE STRASBOURG
    Inventor: Nadia BENKIRANE-JESSEL
  • BIOMATERIALS COMPRISING A SCAFFOLD CONTAINING A MINERAL COMPOUND, AND USES THEREOF AS BONE SUBSTITUTES
    Publication number: 20220096712
    Abstract: The present invention concerns a biomaterial comprising a scaffold containing a mineral component, wherein said mineral component comprises at least one calcium phosphate compound, and wherein said scaffold has a surface coated with an interrupted coating made of multilayered droplets, said multilayered droplets being droplets composed of at least one layer pair consisting of a layer of polyanions and a layer of polycations.
    Type: Application
    Filed: February 13, 2020
    Publication date: March 31, 2022
    Inventors: Fabien BORNERT, Olivier HUCK, Damien OFFNER, Ysia IDOUX-GILLET, François CLAUSS, Nadia BENKIRANE-JESSEL
  • Nano-reservoirs technology for use in bone and/or cartilage regeneration
    Patent number: 10034737
    Abstract: The present invention concerns a biomaterial comprising a nanofibrous scaffold made of polymers, such as poly(?-caprolactone) or collagen, coated with at least one layer pair consisting of a layer of polyanions and a layer of polycations, wherein said at least one layer pair incorporates a therapeutic molecule such as a growth factor. The biomaterial may optionally comprise living cells such as osteoblasts and/or chondrocytes.
    Type: Grant
    Filed: February 22, 2012
    Date of Patent: July 31, 2018
    Assignee: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)
    Inventors: Nadia Benkirane-Jessel, Didier Mainard, Carlos Mendoza Palomares
  • Three-Dimensional Scaffold Functionalized with Micro-Tissues for Tissue Regeneration
    Publication number: 20160136330
    Abstract: The present invention concerns a biomaterial devoid of a growth factor, comprising: —a three-dimensional scaffold made of a biocompatible polymer; and—living cells, wherein said living cells are in form of microtissues and the nanofibrous three-dimensional scaffold is a nanofibrous scaffold. It further concerns a method for manufacturing such a biomaterial. Finally, it concerns such a biomaterial for use in the treatment of a bone and/or cartilage defect.
    Type: Application
    Filed: July 16, 2014
    Publication date: May 19, 2016
    Inventors: Nadia Benkirane-Jessel, Sandy Eap, Laetitia Keller
  • COMPOUND COMPRISING ALPHA-MSH FOR USE IN ENDODONTIC REGENERATION
    Publication number: 20140050773
    Abstract: The present invention concerns a compound comprising an ?-MSH peptide, coupled to a polypeptide consisting of a chain of about 15 to about 400 amino acids, for use in endodontic regeneration and/or for the treatment of dental inflammatory diseases. The invention further concerns pharmaceutical compositions, in particular nanostructured compositions, comprising such a compound.
    Type: Application
    Filed: November 26, 2010
    Publication date: February 20, 2014
    Applicant: Universite De Strasbourg
    Inventors: Nadia Benkirane-Jessel, Carlos Mendoza Palomares, Florence Fioretti
  • NANO-RESERVOIRS TECHNOLOGY FOR USE IN BONE AND/OR CARTILAGE REGENERATION
    Publication number: 20130325144
    Abstract: The present invention concerns a biomaterial comprising a nanofibrous scaffold made of polymers, such as poly(?-caprolactone) or collagen, coated with at least one layer pair consisting of a layer of polyanions and a layer of polycations, wherein said at least one layer pair incorporates a therapeutic molecule such as a growth factor. The biomaterial may optionally comprise living cells such as osteoblasts and/or chondrocytes.
    Type: Application
    Filed: February 22, 2012
    Publication date: December 5, 2013
    Applicant: UNIVERSITÉ DE STRASBOURG
    Inventors: Nadia Benkirane-Jessel, Didier Mainard, Carlos Mendoza Palomares