Abstract: An implantable medical device which is coated with a rapidly releasable substance.

Abstract: In order to provide medical devices having a coating for local prophylaxis and treatment of undesirable cell proliferation and vasoconstriction, a medical device comprising a coating on at least a portion of the surface is proposed, said coating comprising at least one limus substance in non-encapsulated crystalline form, wherein the at least one non-encapsulated limus substance is applied directly from a solvent mixture of at least one organic solvent and water. The formation of crystals of the limus substance can be brought about or enhanced by slowing down the evaporation of the solvent mixture. In addition, a method for preparing the medical devices is proposed.

Abstract: The invention concerns an implantable medical device which is coated with a substance. The invention provides for rapid release of the substance.