Patents by Inventor Nadia Kadi

Nadia Kadi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polypeptides for carbon-carbon bond formation and uses thereof
    Patent number: 10570379
    Abstract: This document describes polypeptides with dual CoA transferase and ?-ketothiolase activities and variants thereof, use of such polypeptides in biosynthetic methods, and non-naturally occurring hosts comprising such polypeptides.
    Type: Grant
    Filed: November 11, 2016
    Date of Patent: February 25, 2020
    Assignee: INVISTA North America S.a.r.l.
    Inventors: Nadia Kadi, Adriana Leonora Botes
  • Mutant polypeptides and uses thereof
    Patent number: 10519433
    Abstract: The present disclosure provides novel polypeptides with 3-buten-2-ol dehydratase activity, polypeptides with catalytic activity in the conversion of 3-methyl-3-buten-2-ol to isoprene, and crystal structure data for one of such polypeptides. Methods of making and using the polypeptides and their related crystal structure data are also provided.
    Type: Grant
    Filed: February 29, 2016
    Date of Patent: December 31, 2019
    Assignee: INVISTA NORTH AMERICA S.A.R.L.
    Inventors: Nadia Kadi, Adriana L. Botes, Mihai Luchian Azoitei, Yih-En A. Ban, Daniela Grabs-Röthlisberger, Alexander Pisarchik, Alexandre Zanghellini, Eric Althoff
  • MUTANT POLYPEPTIDES AND USES THEREOF
    Publication number: 20190300871
    Abstract: The present disclosure provides novel polypeptides with 3-buten-2-ol dehydratase activity, polypeptides with catalytic activity in the conversion of 3-methyl-3-buten-2-ol to isoprene, and crystal structure data for one of such polypeptides. Methods of making and using the polypeptides and their related crystal structure data are also provided.
    Type: Application
    Filed: January 2, 2019
    Publication date: October 3, 2019
    Applicant: INVISTA North America S.à.r.l.
    Inventors: Eric ALTHOFF, Nadia KADI, Mihai AZOITEI, Yih-En A. BAN, Daniela GRABS-RÖTHLISBERGER, Alexander PISARCHIK, Alexandre ZANGHELLINI, Adriana L. BOTES
  • Mutant polypeptides and uses thereof
    Patent number: 10214736
    Abstract: The present disclosure provides novel polypeptides with 3-buten-2-ol dehydratase activity, polypeptides with catalytic activity in the conversion of 3-methyl-3-buten-2-ol to isoprene, and crystal structure data for one of such polypeptides. Methods of making and using the polypeptides and their related crystal structure data are also provided.
    Type: Grant
    Filed: May 12, 2017
    Date of Patent: February 26, 2019
    Assignee: INVISTA North America S.à.r.l.
    Inventors: Eric Althoff, Nadia Kadi, Mihai Luchian Azoitei, Yih-En A. Ban, Daniela Grabs-Röthlisberger, Alexander Pisarchik, Alexandre Zanghellini, Adriana L. Botes
  • MUTANT POLYPEPTIDES AND USES THEREOF
    Publication number: 20180030431
    Abstract: The present disclosure provides novel polypeptides with 3-buten-2-ol dehydratase activity, polypeptides with catalytic activity in the conversion of 3-methyl-3-buten-2-ol to isoprene, and crystal structure data for one of such polypeptides. Methods of making and using the polypeptides and their related crystal structure data are also provided.
    Type: Application
    Filed: May 12, 2017
    Publication date: February 1, 2018
    Applicant: INVISTA North America S.A.R.L.
    Inventors: Eric ALTHOFF, Nadia KADI, Mihai Luchian AZOITEI, Yih-En A. BAN, Daniela GRABS-RÖTHLISBERGER, Alexander PISARCHIK, Alexandre ZANGHELLINI, Adriana L. BOTES
  • Mutant polypeptides and uses thereof
    Patent number: 9683227
    Abstract: The present disclosure provides novel polypeptides with 3-buten-2-ol dehydratase activity, polypeptides with catalytic activity in the conversion of 3-methyl-3-buten-2-ol to isoprene, and crystal structure data for one of such polypeptides. Methods of making and using the polypeptides and their related crystal structure data are also provided.
    Type: Grant
    Filed: August 24, 2015
    Date of Patent: June 20, 2017
    Assignee: INVISTA NORTH AMERICA S.A.R.L.
    Inventors: Eric Althoff, Nadia Kadi, Mihai Luchian Azoitei, Yih-En A Ban, Daniela Grabs-Röthlisberger, Alexander Pisarchik, Alexandre Zanghellini, Adriana L. Botes
  • POLYPEPTIDES FOR CARBON-CARBON BOND FORMATION AND USES THEREOF
    Publication number: 20170159031
    Abstract: This document describes polypeptides with dual CoA transferase and ?-ketothiolase activities and variants thereof, use of such polypeptides in biosynthetic methods, and non-naturally occurring hosts comprising such polypeptides.
    Type: Application
    Filed: November 11, 2016
    Publication date: June 8, 2017
    Inventors: Adriana Leonora Botes, Nadia Kadi
  • MUTANT POLYPEPTIDES AND USES THEREOF
    Publication number: 20160304852
    Abstract: The present disclosure provides novel polypeptides with 3-buten-2-ol dehydratase activity, polypeptides with catalytic activity in the conversion of 3-methyl-3-buten-2-ol to isoprene, and crystal structure data for one of such polypeptides. Methods of making and using the polypeptides and their related crystal structure data are also provided.
    Type: Application
    Filed: August 24, 2015
    Publication date: October 20, 2016
    Applicant: INVISTA S.a.r.l.
    Inventors: Adriana L. Botes, Nadia Kadi, Mihai Luchian Azoitei, Yih-En A. Ban, Daniela Grabs-Röthlisberger, Alexander Pisarchik, Alexandre Zanghellini, Eric Althoff
  • NOVEL POLYPEPTIDES AND USES THEREOF
    Publication number: 20160251644
    Abstract: The present disclosure provides novel polypeptides with improved 3-buten-2-ol dehydratase activity, polypeptides with improved linalool dehydratase activity, and polypeptides with catalytic activity in the conversion of 3-methyl-3-buten-2-ol to isoprene. Methods of making and using the polypeptides are also provided.
    Type: Application
    Filed: February 26, 2016
    Publication date: September 1, 2016
    Applicant: INVISTA NORTH AMERICA S.A.R.L.
    Inventors: ADRIANA L. BOTES, Nadia Kadi
  • MUTANT POLYPEPTIDES AND USES THEREOF
    Publication number: 20160251645
    Abstract: The present disclosure provides novel polypeptides with 3-buten-2-ol dehydratase activity, polypeptides with catalytic activity in the conversion of 3-methyl-3-buten-2-ol to isoprene, and crystal structure data for one of such polypeptides. Methods of making and using the polypeptides and their related crystal structure data are also provided.
    Type: Application
    Filed: February 29, 2016
    Publication date: September 1, 2016
    Applicant: INVISTA North America S.a.r.l.
    Inventors: ADRIANA L. BOTES, Nadia Kadi, Mihai Luchian Azoitei, Yih-En A. Ban, Daniela Grabs-Röthlisberger, Alexander Pisarchik, Alexandre Zanghellini, Eric Althoff
  • Methods and Materials for Producing 6-Carbon Monomers
    Publication number: 20160160255
    Abstract: This document describes biochemical pathways for producing 6-hydroxyhexanoic acid using a polypeptide having ?-ketothiolase activity to form a 3-oxo-6-hydroxyhexanoyl-CoA intermediate. 6-hydroxyhexanoic acid can be enzymatically converted to adipic acid, caprolactam, 6-aminohexanoic acid, hexamethylenediamine or 1,6-hexanediol. This document also describes recombinant hosts producing 6-hydroxyhexanoic acid as well as adipic acid, caprolactam, 6-aminohexanoic acid, hexamethylenediamine and 1,6-hexanediol.
    Type: Application
    Filed: November 13, 2015
    Publication date: June 9, 2016
    Inventors: Adriana Leonora Botes, Alex Van Eck Conradie, Nadia Kadi
  • Mutant polypeptides and uses thereof
    Patent number: 9220742
    Abstract: The present disclosure provides novel polypeptides with 3-buten-2-ol dehydratase activity, polypeptides with catalytic activity in the conversion of 3-methyl-3-buten-2-ol to isoprene, and crystal structure data for one of such polypeptides. Methods of making and using the polypeptides and their related crystal structure data are also provided.
    Type: Grant
    Filed: July 16, 2015
    Date of Patent: December 29, 2015
    Assignee: INVISTA NORTH AMERICA S.A.R.L.
    Inventors: Adriana Botes, Nadia Kadi, Mihai Luchian Azoitei, Yih-En A Ban, Daniela Grabs-Röthlisberger, Alexander Pisarchik, Alexandre Zanghellini, Eric Althoff