Patents by Inventor Nadia Mitchell

Nadia Mitchell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • OPTIMIZED CLN5 GENES AND EXPRESSION CASSETTES AND THEIR USE
    Publication number: 20250129384
    Abstract: This invention relates to polynucleotides comprising optimized CLN5 open reading frame (ORF) sequences, vectors comprising the same, and methods of using the same for delivery of the ORF to a cell or a subject and to treat disorders associated with aberrant expression of a CLN5 gene or aberrant activity of a CLN5 gene product in the subject, such as CLN5 disease.
    Type: Application
    Filed: December 18, 2024
    Publication date: April 24, 2025
    Inventors: Steven James Gray, David Palmer, Nadia Mitchell
  • Optimized CLN5 genes and expression cassettes and their use
    Patent number: 12275948
    Abstract: This invention relates to polynucleotides comprising optimized CLN5 open reading frame (ORF) sequences, vectors comprising the same, and methods of using the same for delivery of the ORF to a cell or a subject and to treat disorders associated with aberrant expression of a CLN5 gene or aberrant activity of a CLN5 gene product in the subject, such as CLN5 disease.
    Type: Grant
    Filed: June 27, 2019
    Date of Patent: April 15, 2025
    Assignees: The University of North Carolina at Chapel Hill, Lincoln University
    Inventors: Steven James Gray, David Palmer, Nadia Mitchell
  • OPTIMIZED CLN5 GENES AND EXPRESSION CASSETTES AND THEIR USE
    Publication number: 20210269829
    Abstract: This invention relates to polynucleotides comprising optimized CLNS open reading frame (ORF) sequences, vectors comprising the same, and methods of using the same for delivery of the ORF to a cell or a subject and to treat disorders associated with aberrant expression of a CLNS gene or aberrant activity of a CLNS gene product in the subject, such as CLNS disease.
    Type: Application
    Filed: June 27, 2019
    Publication date: September 2, 2021
    Inventors: Steven James Gray, David Palmer, Nadia Mitchell