Patents by Inventor Nadia Zaffaroni

Nadia Zaffaroni has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cationic lipids for the transfection of nucleic acids
    Patent number: 7999101
    Abstract: The present invention relates to cationic lipids capable of forming complexes with nucleic acids and the use thereof for the transfection of eukaryotic cells. The cationic lipids according to the invention have general formulas (I) and (Ia): (see formulas (I) and (Ia), wherein E is a heteroaryl; R1 and R2 are selected from H, —R7—NH2, alkyl; R7 is selected from alkyl, alkenyl, aryl, (C1-C20) alkyl-aryl-(C0-C20) alkyl; R3 and R4 are selected from: H, —R8—SH, R8—NH—NH2/—R8—CO—R9 or —R8—NH2; R8 is selected from: alkyl, alkenyl, aryl, (C1-C20) alkyl-aryl-(C0-C20) alkyl; R9 is selected from: H, alkyl; R5 and R6 are selected from: H, alkyl, alkenyl, aryl, (C1-C20) alkyl-aryl.
    Type: Grant
    Filed: February 13, 2006
    Date of Patent: August 16, 2011
    Assignee: Politecnico Di Milano
    Inventors: Matteo Zanda, Luca Bruche′, Massimo Frigerio, Fiorenza Viani, Luca Chiamenti, Walter Panzeri, Nadia Zaffaroni, Marco Folini, Maria Angela Greco
  • Cationic Lipids for the Transfection of Nucleic Acids
    Publication number: 20080146518
    Abstract: The present invention relates to cationic lipids capable of forming complexes with nucleic acids and the use thereof for the transfection of eukaryotic cells. The cationic lipids according to the invention have general formulas (I) and (Ia): (see formulas (I) and (Ia), wherein E is a heteroaryl; R1 and R2 are selected from H, —R7-NH2, aklyl; R7 is selected from alkyl, alkenyl, aryl, (C1-C20) alkyl-aryl-(C0-C20) alkyl; R3 and R4 are selected from: H, —R8-SH, R8-NH—NH2/—R8-CO—R9 or —R8-NH2; R8 is selected from: alkyl, alkenyl, aryl, (C1-C20) alkyl-aryl-(C0-C20) alkyl; R9 is selected from: H, alkyl; R5 and R6 are selected from: H, alkyl, alkenyl, aryl, (C1-C20) alkyl-aryl.
    Type: Application
    Filed: February 13, 2006
    Publication date: June 19, 2008
    Applicant: POLITECNICO DI MILANO
    Inventors: Matteo Zanda, Luca Bruche, Massimo Fricerio, Fiorenza Viani, Luca Chiamenti, Walter Panzeri, Nadia Zaffaroni, Marco Folini, Maria Angela Greco